Duvelisib (IPI-145)

Name: Duvelisib (IPI-145); MyBioSource
Brand: MyBioSource
SKU: MBS3600723
Price: 220 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3600723

A potent, selective PI3Kdelta/gamma inhibitor with Ki of 23 pM/243 pM, IC50 of 1 nM/50 nM. More details

$220 / 2 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Duvelisib, Biochemical

Full Product Name

Duvelisib

Product Synonym Names

IPI-145; INK-1197

Purity/Purification

>98% (HPLC)

Preparation and Storage

Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack

Molecular Weight

416.863

Suitability

DMSO: >=41mg/mL

Target

PI3K

Receptor

PI3Kalpha; PI3Kbeta; PI3Kgamma; PI3Kdelta

Chemical Name

1(2H)-Isoquinolinone, 8-chloro-2-phenyl-3-[(1S)-1-(9H-purin-6-ylamino)ethyl]

SMILES

O=C1N(C2=CC=CC=C2)C([C@@H](NC3=C4N=CNC4=NC=N3)C)=CC5=C1C(Cl)=CC=C5

Molecular Formula

C22H17ClN6O

CAS Number

1201438-56-3

Product Categories/Family for Duvelisib biochemical

Blood cancer; PI3K/Akt/mTOR signaling; Cancer

Product References and Citations for Duvelisib biochemical

1. Winkler DG, et al. Chem Biol. 2013 Nov 21; 20 (11):1364-74.
2. Boyle DL, et al. J Pharmacol Exp Ther. 2014 Feb; 348 (2):271-80.
3. Dong S, et al. Blood. 2014 Dec 4; 124 (24):3583-6.

Other Notes

Small volumes of Duvelisib biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for Duvelisib purchase

MBS3600723 is a biochemical targeting Duvelisib.