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M8-B Hydrochloride

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3611898

M8-B Hydrochloride is a selective transient receptor potential melastatin-8 (TRPM8) channel antagonist.M8 B, a TRPM8 antagonist. More details

$215 / 2 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
M8-B, Biochemical
Full Product Name
M8-B Hydrochloride
Product Gene Name
M8-B biochemical
Purity/Purification
>98% (HPLC)
Preparation and Storage
Store at -20 degree C
Stability: >= 2 years
Molecular Weight
432.96
Receptor
TRPM8
SMILES
Cl.COc1cc(CN(CCN)C(=O)c2cccs2)ccc1OCc1ccccc1
Molecular Formula
C22H25ClN2O3S?
CAS Number
883976-12-3

Product Categories/Family for M8-B biochemical

TRP/TRPV Channel; Membrane Transporter/Ion Channel

Chemical Structure of M8-B biochemical

M8-B Hydrochloride Biochemical – Cat# MBS3611898

Product References and Citations for M8-B biochemical

1. Zandi N , Zaniani N R , Moghimi A , et al. Protective effects of M8?B, a TRPM8 antagonist, on febrile? and pentylenetetrazol?induced seizures[J]. Acta neurobiologiae experimentalis, 2019, 79(1):86-91.
2. Almeida M C , Hew-Butler T , Soriano R N , et al. Pharmacological Blockade of the Cold Receptor TRPM8 Attenuates Autonomic and Behavioral Cold Defenses and Decreases Deep Body Temperature[J]. Journal of Neuroscience, 2012, 32(6):2086-2099.

Other Notes

Small volumes of M8-B biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for M8-B purchase

MBS3611898 is a biochemical targeting M8-B. Also known as M8-B Hydrochloride.
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