SAGE-217 (Zuranolone)

Name: SAGE-217 (Zuranolone); MyBioSource
Brand: MyBioSource
SKU: MBS3602455
Price: 215 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3602455

SAGE-217 (Zuranolone, SAGE217) is a potent, orally active GABAA receptor positive allosteric modulator with EC50 of 296 and 163 nM for alpha1beta2gamma2 and alpha4beta3delta GABAA r eceptors, respectively. More details

$215 / 2 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

SAGE-217, Biochemical

Full Product Name

SAGE-217

Product Synonym Names

Zuranolone; SAGE217

Purity/Purification

>98% (HPLC)

Preparation and Storage

Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack

Molecular Weight

409.574

Suitability

DMSO: >=100mg/mL (244.16mM)

Target

GAT

Receptor

GAT

Chemical Name

1-[2-[(3R, 5R, 8R, 9R, 10S, 13S, 14S, 17S)-3-hydroxy-3, 13-dimethyl-2, 4, 5, 6, 7, 8, 9, 10, 11, 12, 14, 15, 16, 17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]-2-oxoethyl]pyrazole-4-carbonitrile

SMILES

CC1(CCC2C(C1)CCC3C2CCC4(C3CCC4C(=O)CN5C=C(C=N5)C#N)C)O

Molecular Formula

C25H35N3O2

CAS Number

1632051-40-1

Product Categories/Family for SAGE-217 biochemical

Depression; Membrane Transporter/Ion Channel; Neurological Disease

Product References and Citations for SAGE-217 biochemical

1. Martinez Botella G, et al. J Med Chem. 2017 Sep 28; 60 (18):7810-7819.

Other Notes

Small volumes of SAGE-217 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for SAGE-217 purchase

MBS3602455 is a biochemical targeting SAGE-217.