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SCH-527123

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3604571

A potent, selective, orally bioavailable CXCR2/CXCR1 receptor antagonist with Kd of 0.08 and 41 nM for cynomolgus CXCR2 and CXCR1, respectively. More details

$255 / 5 mg +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
SCH-527123, Biochemical
Full Product Name
SCH-527123
Product Synonym Names
SCH527123; Navarixin; SCH 527123; MK-7123
Purity/Purification
>98% (HPLC)
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Molecular Weight
397.4244
Suitability
10mM in DMSO
Target
Chemokine Receptor
Receptor
Chemokine Receptor
Chemical Name
Benzamide, 2-hydroxy-N, N-dimethyl-3-[[2-[[(1R)-1-(5-methyl-2-furanyl)propyl]amino]-3, 4-dioxo-1-cyclobuten-1-yl]amino]
SMILES
O=C(N(C)C)C1=CC=CC(NC2=C(N[C@@H](C3=CC=C(C)O3)CC)C(C2=O)=O)=C1O
Molecular Formula
C21H23N3O5
CAS Number
473727-83-2

Product Categories/Family for SCH-527123 biochemical

COPD; GPCR/G Protein; Inflammation/Immunology

Structure of SCH-527123 biochemical

SCH-527123 Biochemical – Cat# MBS3604571

Product References and Citations for SCH-527123 biochemical

1. Chapman RW, et al. J Pharmacol Exp Ther. 2007 Aug; 322 (2):486-93.
2. Dwyer MP, et al. J Med Chem. 2006 Dec 28; 49 (26):7603-6.
3. Gonsiorek W, et al. J Pharmacol Exp Ther. 2007 Aug; 322 (2):477-85.
4. Singh S, et al. Clin Cancer Res. 2009 Apr 1; 15 (7):2380-6.

Other Notes

Small volumes of SCH-527123 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for SCH-527123 purchase

MBS3604571 is a biochemical targeting SCH-527123.
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