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UNC0379

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3602379

UNC0379 is a selective, substrate-competitive inhibitor of lysine methyltransferase SETD8 with IC50 of 7.3 uM. More details

$235 / 5 mg +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
UNC0379, Biochemical
Full Product Name
UNC0379
Product Synonym Names
UNC 0379; UNC-0379
Purity/Purification
>98% (HPLC)
Preparation and Storage
Store at -20 degree C
Stability: >=2 years
Shipping: Ice Pack
Molecular Weight
413.5563
Suitability
10mM in DMSO
Target
HMTase
Receptor
SETD8
Chemical Name
4-Quinazolinamine, 6, 7-dimethoxy-2-(1-pyrrolidinyl)-N-[5-(1-pyrrolidinyl)pentyl]
SMILES
COC1=C(OC)C=C(N=C(N2CCCC2)N=C3NCCCCCN4CCCC4)C3=C1
Molecular Formula
C23H35N5O2
CAS Number
1620401-82-2

Product Categories/Family for UNC0379 biochemical

Chromatin/Epigenetic; Other Indications

Product References and Citations for UNC0379 biochemical

1. Ma A, et al. J Med Chem. 2014 Aug 14; 57 (15):6822-33.
2. Ma A, et al. Medchemcomm. 2014 Dec; 5 (12):1892-1898.
3. Veschi V, et al. Cancer Cell. 2017 Jan 9; 31 (1):50-63.

Other Notes

Small volumes of UNC0379 biochemical vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for UNC0379 purchase

MBS3602379 is a biochemical targeting UNC0379.
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