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AKR7L Blocking Peptide (N-Term) Blocking Peptide

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS9230100

Can reduce the dialdehyde protein-binding form of aflatoxin B1 (AFB1) to the non-binding AFB1 dialcohol. May be involved in protection of liver against the toxic and carcinogenic effects of AFB1, a potent hepatocarcinogen (By similarity). More details

$455 / 0.5 mg +1 FREE 8GB USB
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Testing Data View PDF
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
AKR7L, Blocking Peptide
Full Product Name
AKR7L Blocking Peptide (N-Term)
Product Gene Name
Product Synonym Gene Name
AFAR3; AKR7A4
Product Synonym Names
Aflatoxin B1 aldehyde reductase member 4; 1---; AFB1 aldehyde reductase 3; AFB1-AR 3; Aldoketoreductase 7-like; AKR7L; AFAR3; AKR7A4
Form/Format
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
Specificity
The synthetic peptide sequence is selected from aa 32-44 of HUMAN AKR7L
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.
Antibody/Peptide Pairs
AKR7L peptide (MBS9230100) is used for blocking the activity of AKR7L antibody (MBS9215639)
Molecular Weight
16,724 Da
OMIM
608478
Tissue Location
Mainly expressed in uterus.

Other Notes

Small volumes of AKR7L blocking peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for AKR7L purchase

MBS9230100 is a blocking peptide targeting AKR7L. Also known as AKR7L Blocking Peptide (N-Term).

Additional Details

NCBI/Uniprot data below describe general gene information for AKR7L. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
Aflatoxin B1 aldehyde reductase member 4
NCBI Official Synonym Full Names
aldo-keto reductase family 7 like (gene/pseudogene)
NCBI Official Symbol
AKR7L
NCBI Official Synonym Symbols
AFAR3; AKR7A4; AFB1-AR3
UniProt Protein Name
Aflatoxin B1 aldehyde reductase member 4
UniProt Synonym Protein Names
AFB1 aldehyde reductase 3; AFB1-AR 3; Aldoketoreductase 7-like
UniProt Gene Name
AKR7L
UniProt Synonym Gene Names
AFAR3; AKR7A4; AFB1-AR 3
UniProt Entry Name
ARK74_HUMAN

NCBI Summary for AKR7L

This gene is one of three aldo-keto reductase genes that are present in a cluster on the p arm of chromosome 1. The encoded proteins are involved in the reduction of the dialdehyde protein-binding form of aflatoxin B1 (AFB1) to the non-binding AFB1 dialcohol. It has been speculated that this family member encodes a selenoprotein, which includes a selenocysteine (Sec) residue in lieu of a UGA translational termination codon. However, there is no evidence that such a protein is produced in vivo. The alternative interpretation is that this family member is a duplicated pseudogene, and it is therefore represented as such in this Gene record. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2011]
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UniProt Comments for AKR7L

AKR7A4: Can reduce the dialdehyde protein-binding form of aflatoxin B1 (AFB1) to the non-binding AFB1 dialcohol. May be involved in protection of liver against the toxic and carcinogenic effects of AFB1, a potent hepatocarcinogen. Belongs to the aldo/keto reductase family. Aldo/keto reductase 2 subfamily. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: EC 1.-.-.-; Oxidoreductase

Chromosomal Location of Human Ortholog: 1p36.13|1p35-p36.1

Cellular Component: cytosol

Molecular Function: aldo-keto reductase activity

Biological Process: xenobiotic metabolic process
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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