AMPH Blocking Peptide – The purity is >90%,tested by HPLC and MS. Purity

Name: AMPH Blocking Peptide; The purity is >90%,tested by HPLC and MS. Purity; MyBioSource
Brand: MyBioSource
SKU: MBS9623940
Price: 460 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS9623940

Blocking peptides are peptides that bind specifically to the target antibody and block antibody binding. These peptide usually contains the epitope recognized by the antibody. Antibodies bound to the blocking peptide no longer bind to the epitope on the… More details

$460 / 1 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

AMPH, Blocking Peptide

Full Product Name

AMPH Blocking Peptide

Product Gene Name

AMPH blocking peptide

Product Synonym Names

Amp; AMPH 1; AMPH; AMPH_HUMAN; AMPH1; Amphiphysin (Stiff-Man syndrome with breast cancer 128kD autoantigen); Amphiphysin (Stiff-Man syndrome with breast cancer 128kDa autoantigen); Amphiphysin; Amphiphysin I; CG8604; Damp; dAmph; DmelCG8604; HGNC:471; MGC49429; Stiff man syndrome with breast cancer 128kD autoantigen; Stiff man syndrome with breast cancer 128kDa autoantigen

Form/Format

Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 10 mg/ml.

Purity/Purification

The purity is >90%,tested by HPLC and MS.

Preparation and Storage

Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.

Antibody/Peptide Pairs

AMPH peptide (MBS9623940) is used for blocking the activity of AMPH antibody (MBS9605223)

Molecular Weight

76,257 Da

Chromosome Location

Chromosome: 7; NC_000007.13 (38423297..38671167, complement). Location: 7p14-p13

OMIM

600418

Supply Chain Verification

Manufactured in a lab with traceable raw materials manufactured on site. Coordinated product portfolio of antibodies, pairs, conjugates, recombinant proteins, and immunoassay materials available, please inquire.

Notes

For phospho antibody, we provide phospho peptide (0.5mg) and non-phospho peptide (0.5mg)

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Applications Tested/Suitable for AMPH blocking peptide

Blocking/Control

Other Notes

Small volumes of AMPH blocking peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for AMPH purchase

MBS9623940 is a blocking peptide targeting AMPH.

Additional Details

NCBI/Uniprot data below describe general gene information for AMPH. It may not necessarily be applicable to this product.

NCBI GI #

4502081

NCBI GeneID

273

NCBI Accession #

NP_001626.1

UniProt Primary Accession #

P49418

UniProt Secondary Accession #

O43538; Q75MJ8; Q75MK5; Q75MM3; Q8N4G0; A4D1X8; A4D1X9

UniProt Related Accession #

P49418

GenBank Nucleotide #

NM_001635.3

NCBI Official Full Name

amphiphysin isoform 1

NCBI Official Synonym Full Names

amphiphysin

NCBI Official Symbol

AMPH

NCBI Official Synonym Symbols

AMPH1

UniProt Protein Name

Amphiphysin

Protein Family

Amphiphysin

UniProt Gene Name

AMPH

UniProt Synonym Gene Names

AMPH1

UniProt Entry Name

AMPH_HUMAN

NCBI Protein Information

amphiphysin; amphiphysin I; amphiphysin (Stiff-Mann syndrome with breast cancer 128kD autoantigen)

NCBI Summary for AMPH

This gene encodes a protein associated with the cytoplasmic surface of synaptic vesicles. A subset of patients with stiff-man syndrome who were also affected by breast cancer are positive for autoantibodies against this protein. Alternate splicing of this gene results in two transcript variants encoding different isoforms. Additional splice variants have been described, but their full length sequences have not been determined. A pseudogene of this gene is found on chromosome 11.[provided by RefSeq, Nov 2010]

UniProt Comments for AMPH

amphiphysin: May participate in mechanisms of regulated exocytosis in synapses and certain endocrine cell types. May control the properties of the membrane associated cytoskeleton. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Vesicle

Chromosomal Location of Human Ortholog: 7p14-p13

Cellular Component: synaptic vesicle; synaptic vesicle membrane; cell junction; actin cytoskeleton

Molecular Function: protein binding; phospholipid binding

Biological Process: synaptic transmission; synaptic vesicle endocytosis; endocytosis; learning

Research Articles on AMPH

1. We propose that antibody-mediated amphiphysin deficiency may account for anxiety behavior in stiff person syndrome

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with AMPH blocking peptide

Reference Product	PubMed Publications
BIN1 blocking peptide	>2 publications with AMPH and BIN1
SH3GL2 blocking peptide	>1 publications with AMPH and SH3GL2

Pathways associated with AMPH blocking peptide

Products by Pathway	Pathway Diagram
Fc Gamma R-mediated Phagocytosis Pathway antibodies	Fc Gamma R-mediated Phagocytosis Pathway Diagram
Fc Gamma R-mediated Phagocytosis Pathway antibodies	Fc Gamma R-mediated Phagocytosis Pathway Diagram
Internalization Of ErbB1 Pathway antibodies	Internalization Of ErbB1 Pathway Diagram
Monoamine Transport Pathway antibodies	Monoamine Transport Pathway Diagram

Diseases associated with AMPH blocking peptide

Disease Name	Pubmed Publications
Drug Toxicity Antibodies	>99 publications with AMPH and Drug Toxicity
Brain Diseases Antibodies	>34 publications with AMPH and Brain Diseases
Immune System Diseases Antibodies	>30 publications with AMPH and Immune System Diseases
Respiratory Tract Diseases Antibodies	>29 publications with AMPH and Respiratory Tract Diseases
Prenatal Exposure Delayed Effects Antibodies	>18 publications with AMPH and Prenatal Exposure Delayed Effects
Inflammation Antibodies	>17 publications with AMPH and Inflammation
Cardiovascular Diseases Antibodies	>15 publications with AMPH and Cardiovascular Diseases
Poisoning Antibodies	>13 publications with AMPH and Poisoning
Body Weight Changes Antibodies	>10 publications with AMPH and Body Weight Changes
Movement Disorders Antibodies	>10 publications with AMPH and Movement Disorders

Organs/Tissues associated with AMPH blocking peptide

Organ/Tissue Name	Pubmed Publications
Brain Antibodies	>609 publications with AMPH and Brain
Lung Antibodies	>35 publications with AMPH and Lung
Kidney Antibodies	>18 publications with AMPH and Kidney
Heart Antibodies	>14 publications with AMPH and Heart
Bone Antibodies	>12 publications with AMPH and Bone
Eye Antibodies	>5 publications with AMPH and Eye
Testis Antibodies	>5 publications with AMPH and Testis
Embryonic Tissue Antibodies	>4 publications with AMPH and Embryonic Tissue
Pineal Gland Antibodies	>3 publications with AMPH and Pineal Gland
Pituitary Gland Antibodies	>2 publications with AMPH and Pituitary Gland