Western blot analysis of BHLHA15 in rat small Intestine tissue lysate with BHLHA15 antibody at 1 μg/ml in (A) the absence and (B) the presence of blocking peptide

BHLHA15 Blocking Peptide

Name: BHLHA15 Blocking Peptide; MyBioSource
Brand: MyBioSource
SKU: MBS153989
Price: 210 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS153989

MBS153989 is a blocking peptide targeting BHLHA15. Also known as BHLHA15 Peptide. More details

$210 / 0.05 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

BHLHA15, Blocking Peptide

Full Product Name

BHLHA15 Peptide

Product Gene Name

BHLHA15 blocking peptide

Product Synonym Names

MIST1; BHLHB8; MIST1; Class A basic helix-loop-helix protein 15; Class B basic helix-loop-helix protein 8; bHLHa15; basic helix-loop-helix family, member a15

Form/Format

Liquid

Concentration

200 ug/mL (lot specific)

Preparation and Storage

Store BHLHA15 peptide at -20 degree C, stable for one year.

Antibody/Peptide Pairs

BHLHA15 peptide (MBS153989) is used for blocking the activity of BHLHA15 antibody (MBS153611)

Molecular Weight

20,818 Da

OMIM

608606

Species

Human

Buffer

PBS pH 7.2 (10 mM NaH2PO4, 10 mM Na2HPO4, 130 mM NaCl) containing 0.1% bovine serum albumin and 0.02% sodium azide

Location

18 amino acids near the center of human BHLHA15.

Applications Tested/Suitable for BHLHA15 blocking peptide

Blocking (BL)

Application Notes for BHLHA15 blocking peptide

The peptide is used for blocking the activity of BHLHA15 antibody. It usually blocks the antibody activity completely by incubating the peptide with equal volume of antibody for 30 min at 37 degree C.

Other Notes

Small volumes of BHLHA15 blocking peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for BHLHA15. It may not necessarily be applicable to this product.

NCBI GI #

29126247

NCBI GeneID

168620

NCBI Accession #

NP_803238

UniProt Primary Accession #

Q7RTS1

UniProt Secondary Accession #

Q14DE4; A4D271

UniProt Related Accession #

Q7RTS1

GenBank Nucleotide #

NM_177455.3

NCBI Official Full Name

class A basic helix-loop-helix protein 15

NCBI Official Synonym Full Names

basic helix-loop-helix family, member a15

NCBI Official Symbol

BHLHA15

NCBI Official Synonym Symbols

MIST1; BHLHB8

UniProt Protein Name

Class A basic helix-loop-helix protein 15

UniProt Synonym Protein Names

Class B basic helix-loop-helix protein 8; bHLHb8; Muscle, intestine and stomach expression 1; MIST-1

Protein Family

Class A basic helix-loop-helix protein

UniProt Gene Name

BHLHA15

UniProt Synonym Gene Names

BHLHB8; MIST1; bHLHa15; bHLHb8; MIST-1

UniProt Entry Name

BHA15_HUMAN

NCBI Protein Information

class A basic helix-loop-helix protein 15; MIST-1; class II bHLH protein MIST1; class B basic helix-loop-helix protein 8; muscle, intestine and stomach expression 1; basic helix-loop-helix domain containing, class B, 8

UniProt Comments for BHLHA15

MIST1: Plays a role in controlling the transcriptional activity of MYOD1, ensuring that expanding myoblast populations remain undifferentiated. Repression may occur through muscle-specific E- box occupancy by homodimers. May also negatively regulate bHLH- mediated transcription through an N-terminal repressor domain. Serves as a key regulator of acinar cell function, stability, and identity. Also required for normal organelle localization in exocrine cells and for mitochondrial calcium ion transport. May function as a unique regulator of gene expression in several different embryonic and postnatal cell lineages. Binds to the E- box consensus sequence 5'-CANNTG-3'.

Chromosomal Location of Human Ortholog: 7q21.3

Cellular Component: nucleus

Molecular Function: protein homodimerization activity

Biological Process: cellular response to glucose starvation; G-protein coupled receptor protein signaling pathway; cell-cell signaling; transcription, DNA-dependent; unfolded protein response; intracellular distribution of mitochondria; cell maturation; calcium-mediated signaling; positive regulation of transcription from RNA polymerase II promoter; glucose homeostasis; mitochondrial calcium ion transport; Golgi organization and biogenesis

Research Articles on BHLHA15

1. noted a higher mean value of microvascular density in CK5/6 and Ep-CAM-immunopositive tumors, carcinomas with aberrant CK8/18 expression, and carcinomas with no or strong expression of MMP-2 in stromal fibroblast-like cells

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with BHLHA15 blocking peptide

Products by Pathway	Pathway Diagram
Maturity Onset Diabetes Of The Young Pathway antibodies	Maturity Onset Diabetes Of The Young Pathway Diagram
Maturity Onset Diabetes Of The Young Pathway antibodies	Maturity Onset Diabetes Of The Young Pathway Diagram

Diseases associated with BHLHA15 blocking peptide

Disease Name	Pubmed Publications
Pancreatitis Antibodies	>1 publications with BHLHA15 and Pancreatitis
Disease Models, Animal Antibodies	>1 publications with BHLHA15 and Disease Models, Animal