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Cofilin Antibody Antigenic Blocking Peptide

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS542769

Antigenic Blocking Peptide Cofilin-1 AntibodyBinds to F-actin and exhibits pH-sensitive depolymerizing activity.  Also regulates cytoskeleton dynamics. More details

$315 / 0.25 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Cofilin (CFL1), Blocking Peptide
Full Product Name
Cofilin Antibody Antigenic Blocking Peptide
Product Gene Name
CFL1 blocking peptide
Product Synonym Names
18 kDa phosphoprotein; CFL 1; epididymis secretory protein Li 15; HEL-S-15; non-muscle isoform; p18 antibody
Form/Format
Antigenic Blocking Peptide
Concentration
Quantity: 250 ug; Volume: 100 ul (lot specific)
Preparation and Storage
-20 degree C for long term storage
Antibody/Peptide Pairs
Cofilin peptide (MBS542769) is used for blocking the activity of Cofilin antibody (MBS540885)
Antibody/Peptide Pairs
Cofilin peptide (MBS542769) is used for blocking the activity of Cofilin antibody (MBS541232)
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Molecular Weight
18,502 Da
OMIM
601442
Immunogen
Synthetic Peptide
Expression
Various tissues
Molecular Function
Actin-Binding
Structure
Contains 1 ADF-H domain and belongs to actin-binding proteins ADF family
Subcellular Location
Cell membrane; Cell projection; Cytoplasm; Cytoskeleton; Membrane; Nucleus
Applications Tested/Suitable for CFL1 blocking peptide
Immunodepletion, Immunocompetition Assay
Application Notes for CFL1 blocking peptide
Western Blot: 1:500

Other Notes

Small volumes of CFL1 blocking peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for CFL1 purchase

MBS542769 is a blocking peptide targeting CFL1. Also known as Cofilin Antibody Antigenic Blocking Peptide.

Additional Details

NCBI/Uniprot data below describe general gene information for CFL1. It may not necessarily be applicable to this product.

NCBI Accession #
BAA00589.1 
UniProt Primary Accession #
P23528
UniProt Secondary Accession #
Q53Y87; Q9UCA2; B3KUQ1
UniProt Protein Name
Cofilin-1
UniProt Synonym Protein Names
18 kDa phosphoprotein; p18; Cofilin, non-muscle isoform
Protein Family
Cofilin
UniProt Gene Name
CFL1
UniProt Synonym Gene Names
CFL; p18
UniProt Entry Name
COF1_HUMAN

UniProt Comments for CFL1

Cofilin-1: a cytoskeletal protein that controls actin depolymerization. Has a 5-10-fold higher affinity for ATP-actin monomers than cofilin-1. May promote filament assembly rather than disassembly. Two alternatively spliced variants are described. Isoform b is expressed predominantly in skeletal muscle and heart, while isoform a is expressed in various tissues.

Protein type: Cytoskeletal; Motility/polarity/chemotaxis; Nuclear receptor co-regulator

Chromosomal Location of Human Ortholog: 11q13

Cellular Component: cytoplasm; extracellular matrix; extracellular space; focal adhesion; membrane; nucleus; vesicle

Molecular Function: actin filament binding; protein binding

Biological Process: actin cytoskeleton organization and biogenesis; actin filament depolymerization; cytoskeleton organization and biogenesis; negative regulation of apoptosis; regulation of cell morphogenesis; response to virus; Rho protein signal transduction
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with CFL1 blocking peptide

 Reference Product  PubMed Publications
 SSH1 blocking peptide  >7 publications with CFL1 and SSH1
 PFN1 blocking peptide  >5 publications with CFL1 and PFN1
 LIMK2 blocking peptide  >4 publications with CFL1 and LIMK2
 WDR1 blocking peptide  >2 publications with CFL1 and WDR1
 ACTB blocking peptide  >2 publications with CFL1 and ACTB

Diseases associated with CFL1 blocking peptide

 Disease Name  Pubmed Publications
 Death Antibodies  >15 publications with CFL1 and Death
 Nervous System Diseases Antibodies  >12 publications with CFL1 and Nervous System Diseases
 Neoplasm Metastasis Antibodies  >12 publications with CFL1 and Neoplasm Metastasis
 Disease Models, Animal Antibodies  >10 publications with CFL1 and Disease Models, Animal
 Breast Neoplasms Antibodies  >10 publications with CFL1 and Breast Neoplasms
 Inflammation Antibodies  >8 publications with CFL1 and Inflammation
 Neoplasm Invasiveness Antibodies  >6 publications with CFL1 and Neoplasm Invasiveness
 Memory Disorders Antibodies  >3 publications with CFL1 and Memory Disorders
 Prenatal Exposure Delayed Effects Antibodies  >2 publications with CFL1 and Prenatal Exposure Delayed Effects
 Seizures Antibodies  >2 publications with CFL1 and Seizures

Organs/Tissues associated with CFL1 blocking peptide

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >24 publications with CFL1 and Brain
 Muscle Antibodies  >17 publications with CFL1 and Muscle
 Blood Antibodies  >15 publications with CFL1 and Blood
 Nerve Antibodies  >14 publications with CFL1 and Nerve
 Lung Antibodies  >10 publications with CFL1 and Lung
 Kidney Antibodies  >6 publications with CFL1 and Kidney
 Uterus Antibodies  >5 publications with CFL1 and Uterus
 Vascular Antibodies  >5 publications with CFL1 and Vascular
 Bone Antibodies  >5 publications with CFL1 and Bone
 Embryonic Tissue Antibodies  >4 publications with CFL1 and Embryonic Tissue
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