Dact2 Blocking Peptide

Name: Dact2 Blocking Peptide; MyBioSource
Brand: MyBioSource
SKU: MBS152860
Price: 210 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS152860

MBS152860 is a blocking peptide targeting DACT2. Also known as Dact2 Peptide. More details

$210 / 0.05 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

Dact2, Blocking Peptide

Full Product Name

Dact2 Peptide

Product Gene Name

DACT2 blocking peptide

Product Synonym Names

DPR2; DAPPER2; C6orf116; bA503C24.7; PP13671; Dapper homolog 2; Dapper antagonist of catenin 2; dapper, antagonist of beta-catenin, homolog 2 (Xenopus laevis)

Form/Format

Liquid

Concentration

200 ug/mL (lot specific)

Preparation and Storage

Store Dact2 peptide at -20 degree C, stable for one year.

Antibody/Peptide Pairs

Dact2 peptide (MBS152860) is used for blocking the activity of Dact2 antibody (MBS150212)

Molecular Weight

29,350 Da

OMIM

608966

Species

Human

Buffer

PBS pH 7.2 (10 mM NaH2PO4, 10 mM Na2HPO4, 130 mM NaCl) containing 0.1% bovine serum albumin and 0.02% sodium azide

Location

12 amino acids near the amino terminus of human Dact2.

Applications Tested/Suitable for DACT2 blocking peptide

Blocking (BL)

Application Notes for DACT2 blocking peptide

Dact2 peptide is used for blocking the activity of Dact2 antibody.

Other Notes

Small volumes of DACT2 blocking peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for DACT2. It may not necessarily be applicable to this product.

NCBI GI #

163965434

NCBI GeneID

168002

NCBI Accession #

NP_999627

UniProt Primary Accession #

Q5SW24

UniProt Secondary Accession #

Q2NKJ2; Q569G0; Q8WYW2

UniProt Related Accession #

Q5SW24

GenBank Nucleotide #

NM_214462.4

NCBI Official Full Name

dapper homolog 2 isoform a

NCBI Official Synonym Full Names

dishevelled-binding antagonist of beta-catenin 2

NCBI Official Symbol

DACT2

NCBI Official Synonym Symbols

DPR2; DAPPER2; C6orf116; bA503C24.7

UniProt Protein Name

Dapper homolog 2

UniProt Synonym Protein Names

Dapper antagonist of catenin 2

Protein Family

Dapper

UniProt Gene Name

DACT2

UniProt Synonym Gene Names

C6orf116

UniProt Entry Name

DACT2_HUMAN

NCBI Protein Information

dapper homolog 2; dapper antagonist of catenin 2; dapper homolog 2, antagonist of beta-catenin; dapper, antagonist of beta-catenin, homolog 2

UniProt Comments for DACT2

DACT2: Involved in regulation of intracellular signaling pathways during development. Negatively regulates the Nodal signaling pathway, possibly by promoting the lysosomal degradation of Nodal receptors, such as TGFBR1. May be involved in control of the morphogenetic behavior of kidney ureteric bud cells by keeping cells epithelial and restraining their mesenchymal character. May play an inhibitory role in the re-epithelialization of skin wounds by attenuating TGF-beta signaling. Belongs to the dapper family. 4 isoforms of the human protein are produced by alternative splicing.

Chromosomal Location of Human Ortholog: 6q27

Cellular Component: mitochondrion

Molecular Function: protein kinase C binding; protein kinase A binding; beta-catenin binding; transcription factor binding

Biological Process: skin development; hemopoietic progenitor cell differentiation; negative regulation of cell adhesion

Research Articles on DACT2

1. Loss of DACT2 expression is associated with esophageal squamous cell carcinoma.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with DACT2 blocking peptide

Reference Product	PubMed Publications
PRICKLE2 blocking peptide	>2 publications with DACT2 and PRICKLE2

Pathways associated with DACT2 blocking peptide

Products by Pathway	Pathway Diagram
TGF-beta Receptor Signaling Pathway antibodies	TGF-beta Receptor Signaling Pathway Diagram

Diseases associated with DACT2 blocking peptide

Disease Name	Pubmed Publications
Carcinoma, Hepatocellular Antibodies	>4 publications with DACT2 and Carcinoma, Hepatocellular
Lung Neoplasms Antibodies	>2 publications with DACT2 and Lung Neoplasms
Neoplasm Metastasis Antibodies	>1 publications with DACT2 and Neoplasm Metastasis
Kidney Diseases Antibodies	>1 publications with DACT2 and Kidney Diseases
Liver Diseases Antibodies	>1 publications with DACT2 and Liver Diseases
Liver Neoplasms Antibodies	>1 publications with DACT2 and Liver Neoplasms

Organs/Tissues associated with DACT2 blocking peptide

Organ/Tissue Name	Pubmed Publications
Embryonic Tissue Antibodies	>4 publications with DACT2 and Embryonic Tissue
Eye Antibodies	>1 publications with DACT2 and Eye
Placenta Antibodies	>1 publications with DACT2 and Placenta