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DNAH2 Antibody (N-Term) Blocking Peptide

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS9221518

Force generating protein of respiratory cilia. Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP. Involved in sperm motility; implicated in sperm flagellar… More details

$455 / 0.5 mg +1 FREE 8GB USB
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Technical Datasheet View PDF
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Product Overview

Online Datasheet in PDF
Product Name
DNAH2, Blocking Peptide
Full Product Name
DNAH2 Antibody (N-term) Blocking Peptide
Product Gene Name
Product Synonym Gene Name
DNAHC2; DNHD3; KIAA1503
Product Synonym Names
Dynein heavy chain 2; axonemal; Axonemal beta dynein heavy chain 2; Ciliary dynein heavy chain 2; Dynein heavy chain domain-containing protein 3; DNAH2; DNAHC2; DNHD3; KIAA1503
Form/Format
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.
Antibody/Peptide Pairs
DNAH2 peptide (MBS9221518) is used for blocking the activity of DNAH2 antibody (MBS9208510)
Molecular Weight
99,915 Da
OMIM
603333
Cellular Location
Cytoplasm, cytoskeleton, cilium axoneme
Tissue Location
Expressed primarily in trachea and testis, 2 tissues containing axonemal structures. Also expressed in lung

Other Notes

Small volumes of DNAH2 blocking peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for DNAH2 purchase

MBS9221518 is a blocking peptide targeting DNAH2. Also known as DNAH2 Antibody (N-term) Blocking Peptide.

Additional Details

NCBI/Uniprot data below describe general gene information for DNAH2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
Dynein heavy chain 2, axonemal
NCBI Official Synonym Full Names
dynein axonemal heavy chain 2
NCBI Official Symbol
DNAH2
NCBI Official Synonym Symbols
DNHD3; DNAHC2
UniProt Protein Name
Dynein heavy chain 2, axonemal
UniProt Synonym Protein Names
Axonemal beta dynein heavy chain 2; Ciliary dynein heavy chain 2; Dynein heavy chain domain-containing protein 3
Protein Family
UniProt Gene Name
DNAH2
UniProt Synonym Gene Names
DNAHC2; DNHD3; KIAA1503
UniProt Entry Name
DYH2_HUMAN
NCBI Protein Information
dynein heavy chain 2, axonemal

NCBI Summary for DNAH2

Dyneins are microtubule-associated motor protein complexes composed of several heavy, light, and intermediate chains. The axonemal dyneins, found in cilia and flagella, are components of the outer and inner dynein arms attached to the peripheral microtubule doublets. DNAH2 is an axonemal inner arm dynein heavy chain (Chapelin et al., 1997 [PubMed 9256245]).[supplied by OMIM, Mar 2008]
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UniProt Comments for DNAH2

DNAH2: Force generating protein of respiratory cilia. Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP. Involved in sperm motility; implicated in sperm flagellar assembly. Belongs to the dynein heavy chain family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 17p13.1
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with DNAH2 blocking peptide

Organs/Tissues associated with DNAH2 blocking peptide

 Organ/Tissue Name  Pubmed Publications
 Kidney Antibodies  >1 publications with DNAH2 and Kidney
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