Rabbit Anti-DNAH2 Polyclonal Antibody – Cat# MBS9208510

DNAH2 Antibody (N-term) western blot analysis in HL-60 cell line lysates (35ug/lane).This demonstrates the DNAH2 antibody detected the DNAH2 protein (arrow).

DNAH2 Antibody – Rabbit Polyclonal

Name: DNAH2 Antibody; Polyclonal; Rabbit; Human-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS9208510
Price: 240 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS9208510

$240 / 0.08 mL +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

DNAH2, Polyclonal Antibody

Full Product Name

DNAH2 Antibody (N-term)

Product Gene Name

anti-DNAH2 antibody

Product Synonym Names

Dynein heavy chain 2; axonemal; Axonemal beta dynein heavy chain 2; Ciliary dynein heavy chain 2; Dynein heavy chain domain-containing protein 3; DNAH2; DNAHC2; DNHD3; KIAA1503

Clonality

Polyclonal

Isotype

Rabbit Ig

Host

Rabbit

Species Reactivity

Human

Form/Format

Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.

Purity/Purification

Peptide Affinity Purified Rabbit Polyclonal Antibody (Pab)

Concentration

Vial Concentration: 0.5 (lot specific)

Specificity

This DNAH2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 440-468 amino acids from the N-terminal region of human DNAH2.

Preparation and Storage

Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C in small aliquots to prevent freeze-thaw cycles.

Antibody/Peptide Pairs

DNAH2 peptide (MBS9221518) is used for blocking the activity of DNAH2 antibody (MBS9208510)

Molecular Weight

507698

Immunogen Sequence Positions

440-468

OMIM

603333

3D Structure

ModBase 3D Structure for Q9P225

Antigen Type

Synthetic Peptide

Antigen Source

HUMAN

Product Categories/Family for anti-DNAH2 antibody

Signal Transduction

Applications Tested/Suitable for anti-DNAH2 antibody

Western Blot (WB), ELISA (EIA)

Application Notes for anti-DNAH2 antibody

WB~~1:1000

Product References and Citations for anti-DNAH2 antibody

Barrett, J.C., et al. Nat. Genet. (2009) In press :
Wistow, G., et al. Mol. Vis. 8, 196-204 (2002) :
Chapelin, C., et al. FEBS Lett. 412(2):325-330(1997)

Other Notes

Small volumes of anti-DNAH2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for DNAH2 purchase

MBS9208510 is an antibody targeting DNAH2. Also known as DNAH2 Antibody (N-term). Reactive in Human. Host: Rabbit.

Additional Details

NCBI/Uniprot data below describe general gene information for DNAH2. It may not necessarily be applicable to this product.

NCBI GI #

75677365

NCBI GeneID

146754

NCBI Accession #

NP_065928.2

UniProt Primary Accession #

Q9P225

UniProt Secondary Accession #

O15434; Q6PIH3; Q6ZR42; A8K992; B5MDX5

UniProt Related Accession #

Q9P225

GenBank Nucleotide #

NM_020877.3

NCBI Official Full Name

dynein heavy chain 2, axonemal isoform 1

NCBI Official Synonym Full Names

dynein, axonemal, heavy chain 2

NCBI Official Symbol

DNAH2

NCBI Official Synonym Symbols

DNHD3; DNAHC2

UniProt Protein Name

Dynein heavy chain 2, axonemal

UniProt Synonym Protein Names

Axonemal beta dynein heavy chain 2; Ciliary dynein heavy chain 2; Dynein heavy chain domain-containing protein 3

Protein Family

Dynein

UniProt Gene Name

DNAH2

UniProt Synonym Gene Names

DNAHC2; DNHD3; KIAA1503

UniProt Entry Name

DYH2_HUMAN

NCBI Protein Information

dynein heavy chain 2, axonemal

NCBI Summary for DNAH2

Dyneins are microtubule-associated motor protein complexes composed of several heavy, light, and intermediate chains. The axonemal dyneins, found in cilia and flagella, are components of the outer and inner dynein arms attached to the peripheral microtubule doublets. DNAH2 is an axonemal inner arm dynein heavy chain (Chapelin et al., 1997 [PubMed 9256245]).[supplied by OMIM, Mar 2008]

UniProt Comments for DNAH2

DNAH2: Force generating protein of respiratory cilia. Produces force towards the minus ends of microtubules. Dynein has ATPase activity; the force-producing power stroke is thought to occur on release of ADP. Involved in sperm motility; implicated in sperm flagellar assembly. Belongs to the dynein heavy chain family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Motility/polarity/chemotaxis

Chromosomal Location of Human Ortholog: 17p13.1

Cellular Component: microtubule; axonemal dynein complex

Molecular Function: ATPase activity; microtubule motor activity; ATP binding

Biological Process: metabolic process; ciliary or flagellar motility; microtubule-based movement

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-DNAH2 antibody

Reference Product	PubMed Publications
DNAH7 antibody	>1 publications with DNAH2 and DNAH7

Diseases associated with anti-DNAH2 antibody

Disease Name	Pubmed Publications
Chromosome Aberrations Antibodies	>1 publications with DNAH2 and Chromosome Aberrations