FOXM1 Blocking Peptide – Cat# MBS9626328

FOXM1 Blocking Peptide – The purity is >90%,tested by HPLC and MS. Purity

Name: FOXM1 Blocking Peptide; The purity is >90%,tested by HPLC and MS. Purity; MyBioSource
Brand: MyBioSource
SKU: MBS9626328
Price: 460 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS9626328

Blocking peptides are peptides that bind specifically to the target antibody and block antibody binding. These peptide usually contains the epitope recognized by the antibody. Antibodies bound to the blocking peptide no longer bind to the epitope on the… More details

$460 / 1 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

FOXM1, Blocking Peptide

Full Product Name

FOXM1 Blocking Peptide

Product Gene Name

FOXM1 blocking peptide

Product Synonym Names

FKHL16; Forkhead box M1; Forkhead box protein M1; forkhead like 16; Forkhead-related protein FKHL16; FOX M1; Foxm1; FOXM1_HUMAN; FOXM1B; Hepatocyte nuclear factor 3 forkhead homolog 11; HFH-11; HFH11; HNF-3/fork-head homolog 11; HNF3; INS1; M phase phosphoprotein 2; M-phase phosphoprotein 2; MPHOSPH2; MPM-2 reactive phosphoprotein 2; MPP2; PIG29; TGT3; Transcription factor Trident; Trident; WIN; Winged-helix factor from INS-1 cells; Winged-helix factor from INS1 cells

Form/Format

Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 10 mg/ml.

Purity/Purification

The purity is >90%,tested by HPLC and MS.

Preparation and Storage

Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.

Antibody/Peptide Pairs

FOXM1 peptide (MBS9626328) is used for blocking the activity of FOXM1 antibody (MBS9607615)

Molecular Weight

88,596 Da

OMIM

602341

Supply Chain Verification

Manufactured in a lab with traceable raw materials manufactured on site. Coordinated product portfolio of antibodies, pairs, conjugates, recombinant proteins, and immunoassay materials available, please inquire.

Notes

For phospho antibody, we provide phospho peptide (0.5mg) and non-phospho peptide (0.5mg)

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Applications Tested/Suitable for FOXM1 blocking peptide

Blocking/Control

Other Notes

Small volumes of FOXM1 blocking peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for FOXM1 purchase

MBS9626328 is a blocking peptide targeting FOXM1.

Additional Details

NCBI/Uniprot data below describe general gene information for FOXM1. It may not necessarily be applicable to this product.

NCBI GI #

340545543

NCBI GeneID

2305

NCBI Accession #

NP_001230017.1

UniProt Primary Accession #

Q08050

UniProt Secondary Accession #

O43258; O43259; O43260; Q4ZGG7; Q9BRL2

UniProt Related Accession #

Q08050

GenBank Nucleotide #

NM_001243088.1

NCBI Official Full Name

forkhead box protein M1 isoform 4

NCBI Official Synonym Full Names

forkhead box M1

NCBI Official Symbol

FOXM1

NCBI Official Synonym Symbols

MPP2; TGT3; HFH11; HNF-3; INS-1; MPP-2; PIG29; FKHL16; FOXM1B; HFH-11; TRIDENT; MPHOSPH2

UniProt Protein Name

Forkhead box protein M1

UniProt Synonym Protein Names

Forkhead-related protein FKHL16; Hepatocyte nuclear factor 3 forkhead homolog 11; HFH-11; HNF-3/fork-head homolog 11; M-phase phosphoprotein 2; MPM-2 reactive phosphoprotein 2; Transcription factor Trident; Winged-helix factor from INS-1 cells

Protein Family

Forkhead box protein

UniProt Gene Name

FOXM1

UniProt Synonym Gene Names

FKHL16; HFH11; MPP2; WIN; HFH-11; HNF-3/fork-head homolog 11

UniProt Entry Name

FOXM1_HUMAN

NCBI Protein Information

forkhead box protein M1; M-phase phosphoprotein 2; HNF-3/fork-head homolog 11; transcription factor Trident; MPM-2 reactive phosphoprotein 2; forkhead-related protein FKHL16; winged-helix factor from INS-1 cells; Forkhead, drosophila, homolog-like 16; hep

NCBI Summary for FOXM1

The protein encoded by this gene is a transcriptional activator involved in cell proliferation. The encoded protein is phosphorylated in M phase and regulates the expression of several cell cycle genes, such as cyclin B1 and cyclin D1. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2011]

UniProt Comments for FOXM1

FOXM1: a transcriptional activator factor. Contains 1 fork-head domain. May play a role in the control of cell proliferation. Appears to be expressed only in adult organs containing proliferating/cycling cells or in response to growth factors. Also expressed in epithelial cell lines derived from tumors. Not expressed in resting cells. Phosphorylated in M (mitotic) phase. Three splice variant isoforms have been described. Isoform 1 and isoform 2 appear to be the only activators of gene transcription. Isoform 3, found in rat, does not seem to exist in human.

Protein type: DNA-binding; Transcription factor

Chromosomal Location of Human Ortholog: 12p13

Cellular Component: nucleoplasm; cytoplasm

Molecular Function: protein binding; DNA binding; sequence-specific DNA binding; transcription factor activity; protein kinase binding

Biological Process: transcription from RNA polymerase II promoter; regulation of Ras protein signal transduction; regulation of cell cycle; positive regulation of transcription, DNA-dependent; negative regulation of transcription from RNA polymerase II promoter; DNA repair; negative regulation of stress-activated MAPK cascade; liver development; cell cycle; regulation of cell proliferation; DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator; regulation of transcription, DNA-dependent; positive regulation of cell proliferation; positive regulation of transcription from RNA polymerase II promoter; mitotic cell cycle; regulation of cell growth; negative regulation of transcription, DNA-dependent; G2/M transition of mitotic cell cycle; vasculogenesis

Research Articles on FOXM1

1. we suggest that FOXM1 may be a potential target for lung cancer therapy.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with FOXM1 blocking peptide

Reference Product	PubMed Publications
CCNB1 blocking peptide	>55 publications with FOXM1 and CCNB1
PLK1 blocking peptide	>23 publications with FOXM1 and PLK1
CDK1 blocking peptide	>23 publications with FOXM1 and CDK1
CDK2 blocking peptide	>15 publications with FOXM1 and CDK2
BIRC5 blocking peptide	>15 publications with FOXM1 and BIRC5
AURKB blocking peptide	>13 publications with FOXM1 and AURKB
CCNB2 blocking peptide	>7 publications with FOXM1 and CCNB2
CENPF blocking peptide	>4 publications with FOXM1 and CENPF
NEK2 blocking peptide	>3 publications with FOXM1 and NEK2
CENPA blocking peptide	>1 publications with FOXM1 and CENPA

Pathways associated with FOXM1 blocking peptide

Products by Pathway	Pathway Diagram
Cell Cycle Pathway antibodies	Cell Cycle Pathway Diagram
Cell Cycle, Mitotic Pathway antibodies	Cell Cycle, Mitotic Pathway Diagram
Cyclin A/B1 Associated Events During G2/M Transition Pathway antibodies	Cyclin A/B1 Associated Events During G2/M Transition Pathway Diagram
FOXM1 Transcription Factor Network Pathway antibodies	FOXM1 Transcription Factor Network Pathway Diagram
G2/M Transition Pathway antibodies	G2/M Transition Pathway Diagram
Mitotic G2-G2/M Phases Pathway antibodies	Mitotic G2-G2/M Phases Pathway Diagram
Polo-like Kinase Mediated Events Pathway antibodies	Polo-like Kinase Mediated Events Pathway Diagram
SIDS Susceptibility Pathways antibodies	SIDS Susceptibility Pathways Diagram

Diseases associated with FOXM1 blocking peptide

Disease Name	Pubmed Publications
Breast Neoplasms Antibodies	>54 publications with FOXM1 and Breast Neoplasms
Liver Diseases Antibodies	>43 publications with FOXM1 and Liver Diseases
Liver Neoplasms Antibodies	>41 publications with FOXM1 and Liver Neoplasms
Lung Neoplasms Antibodies	>39 publications with FOXM1 and Lung Neoplasms
Carcinoma, Hepatocellular Antibodies	>37 publications with FOXM1 and Carcinoma, Hepatocellular
Cell Transformation, Neoplastic Antibodies	>35 publications with FOXM1 and Cell Transformation, Neoplastic
Disease Models, Animal Antibodies	>28 publications with FOXM1 and Disease Models, Animal
Neoplasms, Experimental Antibodies	>26 publications with FOXM1 and Neoplasms, Experimental
Leukemia Antibodies	>23 publications with FOXM1 and Leukemia
Inflammation Antibodies	>15 publications with FOXM1 and Inflammation

Organs/Tissues associated with FOXM1 blocking peptide

Organ/Tissue Name	Pubmed Publications
Liver Antibodies	>89 publications with FOXM1 and Liver
Lung Antibodies	>76 publications with FOXM1 and Lung
Blood Antibodies	>35 publications with FOXM1 and Blood
Brain Antibodies	>35 publications with FOXM1 and Brain
Vascular Antibodies	>34 publications with FOXM1 and Vascular
Prostate Antibodies	>28 publications with FOXM1 and Prostate
Embryonic Tissue Antibodies	>22 publications with FOXM1 and Embryonic Tissue
Lymph Node Antibodies	>20 publications with FOXM1 and Lymph Node
Muscle Antibodies	>20 publications with FOXM1 and Muscle
Lymph Antibodies	>20 publications with FOXM1 and Lymph