FUT6 Blocking Peptide – The purity is >90%,tested by HPLC and MS. Purity

Name: FUT6 Blocking Peptide; The purity is >90%,tested by HPLC and MS. Purity; MyBioSource
Brand: MyBioSource
SKU: MBS9621729
Price: 460 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS9621729

Blocking peptides are peptides that bind specifically to the target antibody and block antibody binding. These peptide usually contains the epitope recognized by the antibody. Antibodies bound to the blocking peptide no longer bind to the epitope on the… More details

$460 / 1 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

FUT6, Blocking Peptide

Full Product Name

FUT6 Blocking Peptide

Product Gene Name

FUT6 blocking peptide

Product Synonym Names

FUT6 Antibody - N-terminal; Alpha (1,3) fucosyltransferase; EC=2.4.1.65; FCT3A; FT1A; Fuc TVI; fucosyltransferase 6 (alpha (1,3) fucosyltransferase); Fucosyltransferase 6; Fucosyltransferase VI; FucT VI; Galactoside 3 L fucosyltransferase;

Form/Format

Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 10 mg/ml.

Purity/Purification

The purity is >90%,tested by HPLC and MS.

Preparation and Storage

Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.

Antibody/Peptide Pairs

FUT6 peptide (MBS9621729) is used for blocking the activity of FUT6 antibody (MBS9611776)

Molecular Weight

359

OMIM

gene 613852

Supply Chain Verification

Manufactured in a lab with traceable raw materials manufactured on site. Coordinated product portfolio of antibodies, pairs, conjugates, recombinant proteins, and immunoassay materials available, please inquire.

Notes

For phospho antibody, we provide phospho peptide (0.5mg) and non-phospho peptide (0.5mg)

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Applications Tested/Suitable for FUT6 blocking peptide

Blocking/Control

Other Notes

Small volumes of FUT6 blocking peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for FUT6 purchase

MBS9621729 is a blocking peptide targeting FUT6.

Additional Details

NCBI/Uniprot data below describe general gene information for FUT6. It may not necessarily be applicable to this product.

NCBI GI #

1730136

NCBI GeneID

2528

NCBI Accession #

P51993.1

UniProt Primary Accession #

P51993

UniProt Secondary Accession #

Q9UND8; A6NEX0; D6W637

UniProt Related Accession #

P51993

NCBI Official Full Name

Alpha-(1,3)-fucosyltransferase 6

NCBI Official Synonym Full Names

fucosyltransferase 6 (alpha (1,3) fucosyltransferase)

NCBI Official Symbol

FUT6

NCBI Official Synonym Symbols

FT1A; FCT3A; Fuc-TVI; FucT-VI

UniProt Protein Name

Alpha-(1,3)-fucosyltransferase 6

UniProt Synonym Protein Names

Fucosyltransferase 6; Fucosyltransferase VI; Fuc-TVI; FucT-VI; Galactoside 3-L-fucosyltransferase

Protein Family

Alpha-(1,3)-fucosyltransferase

UniProt Gene Name

FUT6

UniProt Synonym Gene Names

FCT3A; Fuc-TVI; FucT-VI

UniProt Entry Name

FUT6_HUMAN

NCBI Protein Information

alpha-(1,3)-fucosyltransferase 6; alpha-(1,3)-fucosyltransferase 6; fucosyltransferase VI; galactoside 3-L-fucosyltransferase

NCBI Summary for FUT6

The protein encoded by this gene is a Golgi stack membrane protein that is involved in the creation of sialyl-Lewis X, an E-selectin ligand. Mutations in this gene are a cause of fucosyltransferase-6 deficiency. Two transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]

UniProt Comments for FUT6

FUT6: Enzyme involved in the biosynthesis of the E-Selectin ligand, sialyl-Lewis X. Catalyzes the transfer of fucose from GDP- beta-fucose to alpha-2,3 sialylated substrates. Belongs to the glycosyltransferase 10 family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Transferase; EC 2.4.1.65; Membrane protein, integral; Glycan Metabolism - glycosphingolipid biosynthesis - lacto and neolacto series

Chromosomal Location of Human Ortholog: 19p13.3

Cellular Component: Golgi apparatus; integral to membrane

Molecular Function: 3-galactosyl-N-acetylglucosaminide 4-alpha-L-fucosyltransferase activity; alpha(1,3)-fucosyltransferase activity; fucosyltransferase activity

Biological Process: protein amino acid glycosylation; L-fucose catabolic process

Disease: Fucosyltransferase 6 Deficiency

Research Articles on FUT6

1. Results suggest that FUT4-, FUT6- or FUT8-mediated MDR in human HCC is associated with the activation of the PI3K/Akt pathway and the expression of MRP1.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with FUT6 blocking peptide

Reference Product	PubMed Publications
FUT4 blocking peptide	>15 publications with FUT6 and FUT4
FUT2 blocking peptide	>13 publications with FUT6 and FUT2
FUT1 blocking peptide	>11 publications with FUT6 and FUT1
FUT9 blocking peptide	>3 publications with FUT6 and FUT9
ABO blocking peptide	>3 publications with FUT6 and ABO

Pathways associated with FUT6 blocking peptide

Products by Pathway	Pathway Diagram
Glycosphingolipid Biosynthesis - Lacto And Neolacto Series Pathway antibodies	Glycosphingolipid Biosynthesis - Lacto And Neolacto Series Pathway Diagram
Glycosphingolipid Biosynthesis - Lacto And Neolacto Series Pathway antibodies	Glycosphingolipid Biosynthesis - Lacto And Neolacto Series Pathway Diagram
Metabolic Pathways antibodies	Metabolic Pathways Diagram

Diseases associated with FUT6 blocking peptide

Disease Name	Pubmed Publications
Carcinoma Antibodies	>14 publications with FUT6 and Carcinoma
Liver Neoplasms Antibodies	>7 publications with FUT6 and Liver Neoplasms
Carcinoma, Hepatocellular Antibodies	>6 publications with FUT6 and Carcinoma, Hepatocellular
Liver Diseases Antibodies	>6 publications with FUT6 and Liver Diseases
Pancreatic Neoplasms Antibodies	>3 publications with FUT6 and Pancreatic Neoplasms
Lung Neoplasms Antibodies	>2 publications with FUT6 and Lung Neoplasms
Neoplasm Metastasis Antibodies	>2 publications with FUT6 and Neoplasm Metastasis
Hypertension Antibodies	>1 publications with FUT6 and Hypertension
Prostatic Neoplasms Antibodies	>1 publications with FUT6 and Prostatic Neoplasms
Leukemia, Myeloid, Acute Antibodies	>1 publications with FUT6 and Leukemia, Myeloid, Acute

Organs/Tissues associated with FUT6 blocking peptide

Organ/Tissue Name	Pubmed Publications
Liver Antibodies	>8 publications with FUT6 and Liver
Brain Antibodies	>4 publications with FUT6 and Brain
Kidney Antibodies	>3 publications with FUT6 and Kidney
Stomach Antibodies	>2 publications with FUT6 and Stomach
Prostate Antibodies	>2 publications with FUT6 and Prostate
Intestine Antibodies	>2 publications with FUT6 and Intestine