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PSMD10 Antibody (C-Term) Blocking Peptide

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS9220918

Acts as a chaperone during the assembly of the 26S proteasome, specifically of the PA700/19S regulatory complex (RC). In the initial step of the base subcomplex assembly is part of an intermediate PSMD10:PSMC4:PSMC5:PAAF1 module which probably assembles with… More details

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Product Overview

Online Datasheet in PDF
Product Name
PSMD10, Blocking Peptide
Full Product Name
PSMD10 Antibody (C-term) Blocking Peptide
Product Gene Name
PSMD10 blocking peptide
Product Synonym Names
26S proteasome non-ATPase regulatory subunit 10; 26S proteasome regulatory subunit p28; Gankyrin; p28(GANK); PSMD10
Form/Format
Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 1 mg/ml.
Preparation and Storage
Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.
Antibody/Peptide Pairs
PSMD10 peptide (MBS9220918) is used for blocking the activity of PSMD10 antibody (MBS9212342)
Molecular Weight
16,137 Da
OMIM
300880
Cellular Location
Cytoplasm. Nucleus
Tissue Location
Tends to be up-regulated in cancer cells with RAS mutations, including lung cancers and adenocarconimas (at protein level).

Other Notes

Small volumes of PSMD10 blocking peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for PSMD10 purchase

MBS9220918 is a blocking peptide targeting PSMD10. Also known as PSMD10 Antibody (C-term) Blocking Peptide.

Additional Details

NCBI/Uniprot data below describe general gene information for PSMD10. It may not necessarily be applicable to this product.

NCBI GI #
20532206
NCBI GeneID
5716
NCBI Accession #
O75832.1
UniProt Primary Accession #
O75832
UniProt Secondary Accession #
Q5U0B2; Q8IZK9
UniProt Related Accession #
O75832
NCBI Official Full Name
26S proteasome non-ATPase regulatory subunit 10
NCBI Official Synonym Full Names
proteasome 26S subunit, non-ATPase 10
NCBI Official Symbol
PSMD10
NCBI Official Synonym Symbols
p28; p28(GANK); dJ889N15.2
UniProt Protein Name
26S proteasome non-ATPase regulatory subunit 10
UniProt Synonym Protein Names
26S proteasome regulatory subunit p28; Gankyrin; p28(GANK)
Protein Family
26S proteasome non-ATPase regulatory
UniProt Gene Name
PSMD10
UniProt Entry Name
PSD10_HUMAN
NCBI Protein Information
26S proteasome non-ATPase regulatory subunit 10

NCBI Summary for PSMD10

This gene encodes a subunit of the PA700/19S complex, which is the regulatory component of the 26S proteasome. The 26S proteosome complex is required for ubiquitin-dependent protein degradation. This protein is a non-ATPase subunit that may be involved in protein-protein interactions. Aberrant expression of this gene may paly a role in tumorigenesis. Two transcripts encoding different isoforms have been described. Pseudogenes have been identified on chromosomes 3 and 20.[provided by RefSeq, Mar 2011]
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Research Articles on PSMD10

1. p28GANK expression was increased in metastatic ESCC tissues and cells, and p28GANK knockdown decreased the metastatic ability of ESCC cells.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with PSMD10 blocking peptide

 Reference Product  PubMed Publications
 PSMC4 blocking peptide  >2 publications with PSMD10 and PSMC4
 PSMC1 blocking peptide  >1 publications with PSMD10 and PSMC1

Pathways associated with PSMD10 blocking peptide

 Products by Pathway  Pathway Diagram
 APC/C-mediated Degradation Of Cell Cycle Proteins Pathway antibodies  APC/C-mediated Degradation Of Cell Cycle Proteins Pathway Diagram
 APC/C:Cdc20 Mediated Degradation Of Securin Pathway antibodies  APC/C:Cdc20 Mediated Degradation Of Securin Pathway Diagram
 APC/C:Cdc20 Mediated Degradation Of Mitotic Proteins Pathway antibodies  APC/C:Cdc20 Mediated Degradation Of Mitotic Proteins Pathway Diagram
 APC/C:Cdh1 Mediated Degradation Of Cdc20 And Other APC/C:Cdh1 Targeted Proteins In Late Mitosis/early G1 Pathway antibodies  APC/C:Cdh1 Mediated Degradation Of Cdc20 And Other APC/C:Cdh1 Targeted Proteins In Late Mitosis/early G1 Pathway Diagram
 APC:Cdc20 Mediated Degradation Of Cell Cycle Proteins Prior To Satisfation Of The Cell Cycle Checkpoint Pathway antibodies  APC:Cdc20 Mediated Degradation Of Cell Cycle Proteins Prior To Satisfation Of The Cell Cycle Checkpoint Pathway Diagram
 ARMS-mediated Activation Pathway antibodies  ARMS-mediated Activation Pathway Diagram
 AUF1 (hnRNP D0) Binds And Destabilizes MRNA Pathway antibodies  AUF1 (hnRNP D0) Binds And Destabilizes MRNA Pathway Diagram
 Activation Of APC/C And APC/C:Cdc20 Mediated Degradation Of Mitotic Proteins Pathway antibodies  Activation Of APC/C And APC/C:Cdc20 Mediated Degradation Of Mitotic Proteins Pathway Diagram
 Activation Of NF-kappaB In B Cells Pathway antibodies  Activation Of NF-kappaB In B Cells Pathway Diagram
 Adaptive Immune System Pathway antibodies  Adaptive Immune System Pathway Diagram

Diseases associated with PSMD10 blocking peptide

 Disease Name  Pubmed Publications
 Carcinoma, Hepatocellular Antibodies  >36 publications with PSMD10 and Carcinoma, Hepatocellular
 Liver Diseases Antibodies  >34 publications with PSMD10 and Liver Diseases
 Liver Neoplasms Antibodies  >32 publications with PSMD10 and Liver Neoplasms
 Neoplasm Metastasis Antibodies  >18 publications with PSMD10 and Neoplasm Metastasis
 Disease Models, Animal Antibodies  >10 publications with PSMD10 and Disease Models, Animal
 Neoplasms, Experimental Antibodies  >8 publications with PSMD10 and Neoplasms, Experimental
 Cell Transformation, Neoplastic Antibodies  >8 publications with PSMD10 and Cell Transformation, Neoplastic
 Neoplasm Invasiveness Antibodies  >8 publications with PSMD10 and Neoplasm Invasiveness
 Liver Neoplasms, Experimental Antibodies  >6 publications with PSMD10 and Liver Neoplasms, Experimental
 Lung Neoplasms Antibodies  >5 publications with PSMD10 and Lung Neoplasms

Organs/Tissues associated with PSMD10 blocking peptide

 Organ/Tissue Name  Pubmed Publications
 Lymph Node Antibodies  >7 publications with PSMD10 and Lymph Node
 Lymph Antibodies  >7 publications with PSMD10 and Lymph
 Lung Antibodies  >5 publications with PSMD10 and Lung
 Stomach Antibodies  >5 publications with PSMD10 and Stomach
 Skin Antibodies  >3 publications with PSMD10 and Skin
 Vascular Antibodies  >3 publications with PSMD10 and Vascular
 Brain Antibodies  >3 publications with PSMD10 and Brain
 Uterus Antibodies  >2 publications with PSMD10 and Uterus
 Mouth Antibodies  >2 publications with PSMD10 and Mouth
 Muscle Antibodies  >2 publications with PSMD10 and Muscle
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