SCG5 Blocking Peptide – The purity is >90%,tested by HPLC and MS. Purity

Name: SCG5 Blocking Peptide; The purity is >90%,tested by HPLC and MS. Purity; MyBioSource
Brand: MyBioSource
SKU: MBS9628709
Price: 460 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS9628709

Blocking peptides are peptides that bind specifically to the target antibody and block antibody binding. These peptide usually contains the epitope recognized by the antibody. Antibodies bound to the blocking peptide no longer bind to the epitope on the… More details

$460 / 1 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

SCG5, Blocking Peptide

Full Product Name

SCG5 Blocking Peptide

Product Gene Name

SCG5 blocking peptide

Product Synonym Names

7B2; 7B2 protein; APPG; Neuroendocrine protein 7B2; P7B2; Pituitary polypeptide; Prohormone convertase chaperone; SCG 5; SCG5; Secretogranin 5; Secretogranin V 7B2 protein; Secretogranin5; SecretograninV; Secretory granule endocrine protein I; Secretory granule neuroendocrine protein 1 7B2 protein; Secretory granule neuroendocrine protein 1; Sg V; SGNE 1; SGNE1; SgV

Form/Format

Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 10 mg/ml.

Purity/Purification

The purity is >90%,tested by HPLC and MS.

Preparation and Storage

Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.

Antibody/Peptide Pairs

SCG5 peptide (MBS9628709) is used for blocking the activity of SCG5 antibody (MBS9610005)

Molecular Weight

23,659 Da

OMIM

173120

Supply Chain Verification

Manufactured in a lab with traceable raw materials manufactured on site. Coordinated product portfolio of antibodies, pairs, conjugates, recombinant proteins, and immunoassay materials available, please inquire.

Notes

For phospho antibody, we provide phospho peptide (0.5mg) and non-phospho peptide (0.5mg)

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Applications Tested/Suitable for SCG5 blocking peptide

Blocking/Control

Other Notes

Small volumes of SCG5 blocking peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for SCG5 purchase

MBS9628709 is a blocking peptide targeting SCG5.

Additional Details

NCBI/Uniprot data below describe general gene information for SCG5. It may not necessarily be applicable to this product.

NCBI GI #

221139785

NCBI GeneID

6447

NCBI Accession #

NP_001138229.1

UniProt Primary Accession #

P05408

UniProt Secondary Accession #

P01164; Q6FHD0; Q9BS38

UniProt Related Accession #

P05408

GenBank Nucleotide #

NM_001144757.2

NCBI Official Full Name

neuroendocrine protein 7B2 isoform 1

NCBI Official Synonym Full Names

secretogranin V (7B2 protein)

NCBI Official Symbol

SCG5

NCBI Official Synonym Symbols

7B2; SgV; P7B2; SGNE1

UniProt Protein Name

Neuroendocrine protein 7B2

UniProt Synonym Protein Names

Pituitary polypeptide; Secretogranin V; Secretogranin-5; Secretory granule endocrine protein ICleaved into the following 2 chains:N-terminal peptide; C-terminal peptide

Protein Family

Neuroendocrine protein

UniProt Gene Name

SCG5

UniProt Synonym Gene Names

SGNE1

UniProt Entry Name

7B2_HUMAN

NCBI Protein Information

neuroendocrine protein 7B2; pituitary polypeptide; prohormone convertase chaperone; secretogranin-5; secretory granule endocrine protein I; secretory granule, neuroendocrine protein 1 (7B2 protein)

UniProt Comments for SCG5

7B2: Acts as a molecular chaperone for PCSK2/PC2, preventing its premature activation in the regulated secretory pathway. Binds to inactive PCSK2 in the endoplasmic reticulum and facilitates its transport from there to later compartments of the secretory pathway where it is proteolytically matured and activated. Also required for cleavage of PCSK2 but does not appear to be involved in its folding. Plays a role in regulating pituitary hormone secretion. The C-terminal peptide inhibits PCSK2 in vitro. Belongs to the 7B2 family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Secreted; Secreted, signal peptide; Chaperone

Chromosomal Location of Human Ortholog: 15q13-q14

Cellular Component: extracellular region; secretory granule

Molecular Function: enzyme inhibitor activity; protein binding; GTP binding; unfolded protein binding

Biological Process: intracellular protein transport; neuropeptide signaling pathway; peptide hormone processing; negative regulation of catalytic activity; regulation of hormone secretion

Research Articles on SCG5

1. 7B2 chaperones blocked the cytotoxic effects of exogenous hIAPP

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with SCG5 blocking peptide

Reference Product	PubMed Publications
PCSK2 blocking peptide	>2 publications with SCG5 and PCSK2
OXT blocking peptide	>1 publications with SCG5 and OXT

Diseases associated with SCG5 blocking peptide

Disease Name	Pubmed Publications
Nervous System Diseases Antibodies	>27 publications with SCG5 and Nervous System Diseases
Carcinoma Antibodies	>14 publications with SCG5 and Carcinoma
Adenocarcinoma Antibodies	>6 publications with SCG5 and Adenocarcinoma
Kidney Diseases Antibodies	>5 publications with SCG5 and Kidney Diseases
Lung Neoplasms Antibodies	>5 publications with SCG5 and Lung Neoplasms
Musculoskeletal Diseases Antibodies	>4 publications with SCG5 and Musculoskeletal Diseases
Colorectal Neoplasms Antibodies	>3 publications with SCG5 and Colorectal Neoplasms
Inflammation Antibodies	>2 publications with SCG5 and Inflammation
Liver Diseases Antibodies	>2 publications with SCG5 and Liver Diseases
Hyperplasia Antibodies	>2 publications with SCG5 and Hyperplasia

Organs/Tissues associated with SCG5 blocking peptide

Organ/Tissue Name	Pubmed Publications
Nerve Antibodies	>86 publications with SCG5 and Nerve
Blood Antibodies	>27 publications with SCG5 and Blood
Brain Antibodies	>21 publications with SCG5 and Brain
Pituitary Gland Antibodies	>18 publications with SCG5 and Pituitary Gland
Pancreas Antibodies	>11 publications with SCG5 and Pancreas
Thyroid Antibodies	>8 publications with SCG5 and Thyroid
Embryonic Tissue Antibodies	>7 publications with SCG5 and Embryonic Tissue
Kidney Antibodies	>7 publications with SCG5 and Kidney
Lung Antibodies	>5 publications with SCG5 and Lung
Skin Antibodies	>4 publications with SCG5 and Skin