SKAP2 Blocking Peptide – Cat# MBS9620790

SKAP2 Blocking Peptide – The purity is >90%,tested by HPLC and MS. Purity

Name: SKAP2 Blocking Peptide; The purity is >90%,tested by HPLC and MS. Purity; MyBioSource
Brand: MyBioSource
SKU: MBS9620790
Price: 460 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS9620790

Blocking peptides are peptides that bind specifically to the target antibody and block antibody binding. These peptide usually contains the epitope recognized by the antibody. Antibodies bound to the blocking peptide no longer bind to the epitope on the… More details

$460 / 1 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

SKAP2, Blocking Peptide

Full Product Name

SKAP2 Blocking Peptide

Product Gene Name

SKAP2 blocking peptide

Product Synonym Names

Fyn associated phosphoprotein SKAP55 homologue; MGC10411; MGC33; PRAP; Pyk2/RAFTK associated protein; Pyk2/RAFTK-associated protein; RA70; Retinoic acid-induced protein 70; SAPS; SKAP-55HOM; SKAP-HOM; skap2; SKAP2_HUMAN; SKAP55 homolog; SKAP55R; Src associated adaptor protein; Src family associated phosphoprotein 2; Src family-associated phosphoprotein 2; src kinase associated phosphoprotein of 55 related protein; Src kinase-associated phosphoprotein 2; Src kinase-associated phosphoprotein 55-related protein; Src-associated adapter protein with PH and SH3 domains

Form/Format

Synthetic peptide was lyophilized with 100% acetonitrile and is supplied as a powder. Reconstitute with 0.1 ml DI water for a final concentration of 10 mg/ml.

Purity/Purification

The purity is >90%,tested by HPLC and MS.

Preparation and Storage

Maintain refrigerated at 2-8 degree C for up to 6 months. For long term storage store at -20 degree C.

Antibody/Peptide Pairs

SKAP2 peptide (MBS9620790) is used for blocking the activity of SKAP2 antibody (MBS9603313)

Molecular Weight

41,217 Da

OMIM

605215

Supply Chain Verification

Manufactured in a lab with traceable raw materials manufactured on site. Coordinated product portfolio of antibodies, pairs, conjugates, recombinant proteins, and immunoassay materials available, please inquire.

Notes

For phospho antibody, we provide phospho peptide (0.5mg) and non-phospho peptide (0.5mg)

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Applications Tested/Suitable for SKAP2 blocking peptide

Blocking/Control

Other Notes

Small volumes of SKAP2 blocking peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for SKAP2 purchase

MBS9620790 is a blocking peptide targeting SKAP2.

Additional Details

NCBI/Uniprot data below describe general gene information for SKAP2. It may not necessarily be applicable to this product.

NCBI GI #

744066863

NCBI GeneID

8935

NCBI Accession #

NP_001290397.1

UniProt Primary Accession #

O75563

UniProt Secondary Accession #

Q53GP6; Q75MK6; Q75MZ4; Q9UBZ3; Q9UED8; A4D173

UniProt Related Accession #

O75563

GenBank Nucleotide #

NM_001303468.1

NCBI Official Full Name

src kinase-associated phosphoprotein 2 isoform 2

NCBI Official Synonym Full Names

src kinase associated phosphoprotein 2

NCBI Official Symbol

SKAP2

NCBI Official Synonym Symbols

PRAP; RA70; SAPS; SCAP2; SKAP55R; SKAP-HOM

UniProt Protein Name

Src kinase-associated phosphoprotein 2

UniProt Synonym Protein Names

Pyk2/RAFTK-associated protein; Retinoic acid-induced protein 70; SKAP55 homolog; SKAP-55HOM; SKAP-HOM; Src family-associated phosphoprotein 2; Src kinase-associated phosphoprotein 55-related protein; Src-associated adapter protein with PH and SH3 domains

Protein Family

Src kinase-associated phosphoprotein

UniProt Gene Name

SKAP2

UniProt Synonym Gene Names

PRAP; RA70; SAPS; SCAP2; SKAP55R; SKAP-55HOM; SKAP-HOM

UniProt Entry Name

SKAP2_HUMAN

NCBI Protein Information

src kinase-associated phosphoprotein 2

NCBI Summary for SKAP2

The protein encoded by this gene shares homology with Src kinase-associated phosphoprotein 1, and is a substrate of Src family kinases. It is an adaptor protein that is thought to play an essential role in the Src signaling pathway, and in regulating proper activation of the immune system. This protein contains an amino terminal coiled-coil domain for self-dimerization, a plecskstrin homology (PH) domain required for interactions with lipids at the membrane, and a Src homology (SH3) domain at the carboxy terminus. Some reports indicate that this protein inhibits actin polymerization through interactions with actin assembly factors, and might negatively regulate the invasiveness of tumors by modulating actin assembly. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2015]

Research Articles on SKAP2

1. Macrophages assemble the appropriate motile machinery to infiltrate tumors and promote disease progression, and implicate SKAP2 as an attractive candidate for therapeutically targeting TAMs.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with SKAP2 blocking peptide

Reference Product	PubMed Publications
CTTN blocking peptide	>1 publications with SKAP2 and CTTN
WASF2 blocking peptide	>1 publications with SKAP2 and WASF2
PTPN22 blocking peptide	>1 publications with SKAP2 and PTPN22
FYB blocking peptide	>1 publications with SKAP2 and FYB

Pathways associated with SKAP2 blocking peptide

Products by Pathway	Pathway Diagram
Cell-Cell Communication Pathway antibodies	Cell-Cell Communication Pathway Diagram
Signal Regulatory Protein (SIRP) Family Interactions Pathway antibodies	Signal Regulatory Protein (SIRP) Family Interactions Pathway Diagram

Diseases associated with SKAP2 blocking peptide

Disease Name	Pubmed Publications
Lung Neoplasms Antibodies	>2 publications with SKAP2 and Lung Neoplasms
Lung Diseases Antibodies	>1 publications with SKAP2 and Lung Diseases
Cardiovascular Diseases Antibodies	>1 publications with SKAP2 and Cardiovascular Diseases
Myocardial Infarction Antibodies	>1 publications with SKAP2 and Myocardial Infarction
Adenocarcinoma Antibodies	>1 publications with SKAP2 and Adenocarcinoma
Neoplasms, Experimental Antibodies	>1 publications with SKAP2 and Neoplasms, Experimental
Breast Neoplasms Antibodies	>1 publications with SKAP2 and Breast Neoplasms
Neoplasm Metastasis Antibodies	>1 publications with SKAP2 and Neoplasm Metastasis
Urogenital Abnormalities Antibodies	>1 publications with SKAP2 and Urogenital Abnormalities

Organs/Tissues associated with SKAP2 blocking peptide

Organ/Tissue Name	Pubmed Publications
Blood Antibodies	>4 publications with SKAP2 and Blood
Lung Antibodies	>2 publications with SKAP2 and Lung
Ovary Antibodies	>1 publications with SKAP2 and Ovary
Bone Antibodies	>1 publications with SKAP2 and Bone
Bone Marrow Antibodies	>1 publications with SKAP2 and Bone Marrow
Heart Antibodies	>1 publications with SKAP2 and Heart
Vascular Antibodies	>1 publications with SKAP2 and Vascular
Eye Antibodies	>1 publications with SKAP2 and Eye
Brain Antibodies	>1 publications with SKAP2 and Brain