Human ACAP1 cDNA Clone Expression Plasmid – Cat# MBS1269946

ACAP1 cDNA Clone – Arfgap with Coiled-Coil, Ankyrin Repeat and Ph Domains 1 (Human)

Name: ACAP1 cDNA Clone; Human; MyBioSource
Brand: MyBioSource
SKU: MBS1269946
Price: 520 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1269946

MBS1269946 is a cDNA clone targeting ACAP1. More details

$520 / 0.01 mg Plasmid + 0.2 mL Glycerol-Stock +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

ACAP1, cDNA Clone

Full Product Name

ACAP1 cDNA Clone

Product Gene Name

ACAP1 cdna clone

Sequence

atgacggtca agctggattt cgaggagtgt ctcaaggact caccccgttt ccgagcctct attgagctgg tggaagccga agtgtcagaa ttggagaccc gtctggaaaa gctcctgaaa ctgggcactg gtctcctgga aagtgggcgc cattaccttg ctgccagccg cgccttcgtt gtcggcattt gtgacctggc ccgcctgggt ccaccagagc ccatgatggc ggagtgtctg gaaaaattca ccgtgagcct gaaccacaag ctggacagcc atgcggagct tctagatgcc acccaacaca cactgcagca gcagatccag accctggtca aggaaggtct gcggggtttc cgagaggctc gccgggattt ctggcggggg gctgagagcc tggaggctgc cctgacccac aacgcagagg ttcccaggcg ccgggcccag gaggcagaag aggcaggagc tgctttgagg acggctcgag ctgggtaccg gggacgggca ctggattatg ccctgcagat caacgtgatt gaggacaaga ggaagtttga catcatggag tttgtgctgc gtttggtgga ggcccaggct acccatttcc agcagggcca tgaggagctg agccggctgt cccagtatcg aaaggagctg ggcgcccagt tgcaccagct ggtcttgaat tcagcacgag agaagaggga catggagcag agacacgtgc tgctgaaaca gaaggagctg ggtggggagg agccagaacc aagcttaaga gaggggcctg gtggcctggt gatggaagga catctcttca aacgggccag caacgcattt aagacctgga gcagacgctg gttcaccatt cagagcaacc aactggttta ccagaagaag tacaaggacc ctgtgactgt ggtggtggat gaccttcgtc tctgcacagt gaaactctgc cctgactcag aaaggcggtt ctgctttgag gtggtgtcca ccagcaagtc ctgcctcctc caggctgact cagagcgcct cctgcagctg tgggtcagtg ctgtgcagag cagcattgct tctgccttca gtcaggctcg ccttgatgac agcccccggg gtccaggcca gggctcagga cacctggcca taggctctgc tgccaccctg ggctctggtg gaatggccag gggaagggag cctgggggag tcgggcacgt ggtggcccag gtccagagtg tggatggcaa tgcccagtgc tgcgactgcc gggagccagc cccggagtgg gccagcatca accttggtgt caccctctgc attcagtgtt ccggcatcca caggagcctt ggtgttcact tctccaaagt ccggtctctg acccttgact catgggagcc agaactagtg aagctcatgt gtgagctggg aaatgtcatc atcaaccaga tctatgaggc ccgcgtggag gccatggcag tgaagaaacc agggcccagc tgctcccggc aggagaagga ggcctggatt cacgctaaat acgtggagaa gaagttcctg accaagctgc ctgagattcg agggcgaaga ggtggccggg ggcgcccaag ggggcagcct cctgtgcccc caaagccttc catcaggccc cggccaggga gcttgagatc caagccagag cccccctctg aggacctggg aagcctgcac cctggggccc tactgtttcg agcgtctggg catcctccat ctcttcccac catggctgat gcccttgccc atggagctga tgtcaactgg gtcaatgggg gccaagataa tgccacaccg ctgatccagg ccacagctgc taattctctt ctggcctgtg agtttctcct ccagaacggg gcgaacgtga accaagcgga cagtgcgggc cggggcccgc tgcaccacgc aaccattctt ggccacacgg ggctcgcctg cctgttcctg aaacggggag ctgatctggg ggctcgagac tctgaaggca gggaccctct gaccatcgcc atggaaacag ccaacgctga catcgtcacc ctgctacgac tggcaaagat gagggaggct gaagcggccc aggggcaggc aggagatgag acgtatcttg acatcttccg cgacttctcc ctcatggcgt cagacgaccc ggagaagctg agccgtcgca gtcatgacct ccacacgctg tga

Molecular Weight

81,536 Da

OMIM

607763

Vector

pENTR223.1 or pUC

Clone Sequence Report

Provided with product shipment

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of ACAP1 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for ACAP1. It may not necessarily be applicable to this product.

NCBI GI #

17391288

NCBI GeneID

9744

NCBI Accession #

BC018543

UniProt Secondary Accession #

Q53XN9

UniProt Related Accession #

Q15027

NCBI Official Full Name

Homo sapiens ArfGAP with coiled-coil, ankyrin repeat and PH domains 1, mRNA

NCBI Official Synonym Full Names

ArfGAP with coiled-coil, ankyrin repeat and PH domains 1

NCBI Official Symbol

ACAP1

NCBI Official Synonym Symbols

CENTB1

UniProt Protein Name

Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1

UniProt Synonym Protein Names

Centaurin-beta-1; Cnt-b1

Protein Family

Arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein

UniProt Gene Name

ACAP1

UniProt Synonym Gene Names

CENTB1; KIAA0050; Cnt-b1

UniProt Entry Name

ACAP1_HUMAN

NCBI Protein Information

arf-GAP with coiled-coil, ANK repeat and PH domain-containing protein 1

UniProt Comments for ACAP1

CENTB1: a member of the centaurin family of ADP-ribosylation factor directed GTPase-activating proteins (GAPs). A GAP for ARF1 and ARF5. Two alternatively-spliced isoforms have been described. Isoform 1 is brain-specific, and isoform 2 is ubiquitously expressed, with highest levels in brain and heart. Isoform 1 participates to the prevention of neuronal apoptosis by enhancing PI3 kinase activity. It aids the coupling of metabotropic glutamate receptor 1 (GRM1) to cytoplasmic PI3 kinase by interacting with Homer scaffolding proteins, and also seems to mediate anti-apoptotic effects of NGF by activating nuclear PI3 kinase. Isoform 2 does not stimulate PI3 kinase but may protect cells from apoptosis by stimulating Akt. Regulates the adapter protein 1 (AP-1)-dependent trafficking of proteins in the endosomal system. The PH domains of isoforms 1 and 2 bind phospholipids, but they differentially regulate subcellular location. The PH domain of isoform 1 directs the protein to the nucleus, but the PH domain of isoform 2 directs it to the cytosol.

Protein type: GAPs; Motility/polarity/chemotaxis; GAPs, ARF

Chromosomal Location of Human Ortholog: 17p13.1

Cellular Component: membrane

Molecular Function: protein binding

Research Articles on ACAP1

1. The serum lever of Alzheimer's disease were decrease and the expression of ACAP1 strongly correlated with the Mini-Mental State Examination scores of the AD patients

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with ACAP1 cdna clone

Products by Pathway	Pathway Diagram
Arf6 Signaling Events Pathway antibodies	Arf6 Signaling Events Pathway Diagram
Arf6 Trafficking Events Pathway antibodies	Arf6 Trafficking Events Pathway Diagram
Endocytosis Pathway antibodies	Endocytosis Pathway Diagram
Endocytosis Pathway antibodies	Endocytosis Pathway Diagram
NOD Pathway antibodies	NOD Pathway Diagram

Diseases associated with ACAP1 cdna clone

Disease Name	Pubmed Publications
Necrosis Antibodies	>1 publications with ACAP1 and Necrosis
Disease Models, Animal Antibodies	>1 publications with ACAP1 and Disease Models, Animal

Organs/Tissues associated with ACAP1 cdna clone

Organ/Tissue Name	Pubmed Publications
Brain Antibodies	>2 publications with ACAP1 and Brain
Nerve Antibodies	>1 publications with ACAP1 and Nerve
Muscle Antibodies	>1 publications with ACAP1 and Muscle
Heart Antibodies	>1 publications with ACAP1 and Heart
Vascular Antibodies	>1 publications with ACAP1 and Vascular
Lung Antibodies	>1 publications with ACAP1 and Lung
Blood Antibodies	>1 publications with ACAP1 and Blood