Human AHSG cDNA Clone Expression Plasmid – Cat# MBS1276013

AHSG cDNA Clone – Alpha-2-Hs-Glycoprotein (Human)

Name: AHSG cDNA Clone; Alpha-2-Hs-Glycoprotein; Human; MyBioSource
Brand: MyBioSource
SKU: MBS1276013
Price: 235 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1276013

MBS1276013 is a cDNA clone targeting AHSG. More details

$235 / 0.01 mg Plasmid + 0.2 mL Glycerol-Stock +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

AHSG, cDNA Clone

Full Product Name

AHSG cDNA Clone

Product Gene Name

AHSG cdna clone

Sequence

atgaagtccc tcgtcctgct cctttgtctt gctcagctgt ggggctgcca ctcagcccca catggcccag ggctgattta tagacaaccg aactgcgatg atccagaaac tgaggaagca gctctggtgg ctatagacta catcaatcaa aaccttcctt ggggatacaa acacaccttg aaccagattg atgaagtaaa ggtgtggcct cagcagccct ccggagagct gtttgagatt gaaatagaca ccctggaaac cacctgccat gtgctggacc ccacccctgt ggcaagatgc agcgtgaggc agctgaagga gcatgctgtc gaaggagact gtgatttcca gctgttgaaa ctagatggca agttttccgt ggtatacgca aaatgtgatt ccagtccaga ctcagccgag gacgtgcgca aggtgtgcca agactgcccc ctgctggccc cgctgaacga caccagggtg gtgcacgccg cgaaagctgc cctggccgcc ttcaacgctc agaacaacgg ctccaatttt cagctggagg aaatttcccg ggctcagctt gtgcccctcc caccttctac ctatgtggag tttacagtgt ctggcactga ctgtgttgct aaagaggcca cagaggcagc caagtgtaac ctgctggcag aaaagcaata tggcttttgt aaggcaacac tcagtgagaa gcttggtggg gcagaggttg cagtgacctg cacggtgttc caaacacagc ccgtgacctc acagccccaa ccagaaggtg ccaatgaagc agtccccacc cccgtggtgg acccagatgc acctccgtcc cctccacttg gcgcacctgg actccctcca gctggctcac ccccagactc ccatgtgtta ctggcagctc ctccaggaca ccagttgcac cgggcgcact acgacctgcg ccacaccttc atgggtgtgg tctcattggg gtcaccctca ggagaagtgt cgcacccccg gaaaacacgc acagtggtgc agcctagtgt tggtgctgct gctgggccag tggttcctcc atgtccgggg aggatcagac acttcaaggt ctag

Molecular Weight

39,325 Da

OMIM

138680

Vector

pENTR223.1

Clone Sequence Report

Provided with product shipment

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of AHSG cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for AHSG. It may not necessarily be applicable to this product.

NCBI GI #

30851644

NCBI GeneID

197

NCBI Accession #

BC052590

UniProt Secondary Accession #

O14961; O14962; Q9P152; A8K9N6; B2R7G1

UniProt Related Accession #

P02765; AAB29984

NCBI Official Full Name

Homo sapiens alpha-2-HS-glycoprotein, mRNA

NCBI Official Synonym Full Names

alpha 2-HS glycoprotein

NCBI Official Symbol

AHSG

NCBI Official Synonym Symbols

AHS; A2HS; HSGA; FETUA

UniProt Protein Name

Alpha-2-HS-glycoprotein

UniProt Synonym Protein Names

Alpha-2-Z-globulin; Ba-alpha-2-glycoprotein; Fetuin-A

Protein Family

Alpha-2-HS-glycoprotein

UniProt Gene Name

AHSG

UniProt Synonym Gene Names

FETUA

UniProt Entry Name

FETUA_HUMAN

NCBI Protein Information

alpha-2-HS-glycoprotein

NCBI Summary for AHSG

Alpha2-HS glycoprotein (AHSG), a glycoprotein present in the serum, is synthesized by hepatocytes. The AHSG molecule consists of two polypeptide chains, which are both cleaved from a proprotein encoded from a single mRNA. It is involved in several functions, such as endocytosis, brain development and the formation of bone tissue. The protein is commonly present in the cortical plate of the immature cerebral cortex and bone marrow hemopoietic matrix, and it has therefore been postulated that it participates in the development of the tissues. However, its exact significance is still obscure. [provided by RefSeq, Jul 2008]

UniProt Comments for AHSG

FETUA: Promotes endocytosis, possesses opsonic properties and influences the mineral phase of bone. Shows affinity for calcium and barium ions. Alpha-2-HS glycoprotein derives from this precursor, when the connecting peptide is cleaved off. The two chains A and B are held together by a single disulfide bond. Synthesized in liver and selectively concentrated in bone matrix. Secreted in plasma. It is also found in dentin in much higher quantities than other plasma proteins. Belongs to the fetuin family.

Protein type: Secreted; Secreted, signal peptide

Chromosomal Location of Human Ortholog: 3q27

Cellular Component: extracellular matrix; extracellular region; extracellular space

Molecular Function: endopeptidase inhibitor activity

Biological Process: acute-phase response; negative regulation of bone mineralization; platelet degranulation; positive regulation of phagocytosis; regulation of inflammatory response

Research Articles on AHSG

1. Data suggest that serum fetuin-A (FETUA/AHSG) concentrations are signi fi cantly positively associated with serum VEGFA (vascular endothelial growth factor A) levels in patients with newly diagnosed type 2 diabetes.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with AHSG cdna clone

Products by Pathway	Pathway Diagram
BMP Receptor Signaling Pathway antibodies	BMP Receptor Signaling Pathway Diagram

Diseases associated with AHSG cdna clone

Disease Name	Pubmed Publications
Cardiovascular Diseases Antibodies	>130 publications with AHSG and Cardiovascular Diseases
Kidney Diseases Antibodies	>104 publications with AHSG and Kidney Diseases
Calcinosis Antibodies	>92 publications with AHSG and Calcinosis
Inflammation Antibodies	>76 publications with AHSG and Inflammation
Neoplasms Antibodies	>54 publications with AHSG and Neoplasms
Heart Diseases Antibodies	>49 publications with AHSG and Heart Diseases
Liver Diseases Antibodies	>35 publications with AHSG and Liver Diseases
Brain Diseases Antibodies	>19 publications with AHSG and Brain Diseases
Liver Neoplasms Antibodies	>17 publications with AHSG and Liver Neoplasms
Hypertension Antibodies	>17 publications with AHSG and Hypertension

Organs/Tissues associated with AHSG cdna clone

Organ/Tissue Name	Pubmed Publications
Blood Antibodies	>467 publications with AHSG and Blood
Liver Antibodies	>79 publications with AHSG and Liver
Heart Antibodies	>35 publications with AHSG and Heart
Muscle Antibodies	>31 publications with AHSG and Muscle
Brain Antibodies	>18 publications with AHSG and Brain
Lung Antibodies	>10 publications with AHSG and Lung
Embryonic Tissue Antibodies	>4 publications with AHSG and Embryonic Tissue
Spleen Antibodies	>3 publications with AHSG and Spleen
Thymus Antibodies	>2 publications with AHSG and Thymus
Testis Antibodies	>2 publications with AHSG and Testis