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ARRDC3 cDNA Clone – Arrestin Domain Containing 3 (Human)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1276297

MBS1276297 is a cDNA clone targeting ARRDC3. More details

$235 / 0.01 mg Plasmid + 0.2 mL Glycerol-Stock +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
ARRDC3, cDNA Clone
Full Product Name
ARRDC3 cDNA Clone
Product Gene Name
ARRDC3 cdna clone
Sequence
atggtgctgg gaaaggtgaa gagtttgaca ataagctttg actgtcttaa tgacagcaat gtccctgtgt attctagtgg ggataccgtc tcaggaaggg taaatttaga agttactggg gaaatcagag taaaatctct taaaattcat gcaagaggac atgcgaaagt acgctggact gaatctagaa acgccggctc caatactgcc tatacacaga attacactga agaagtagag tatttcaacc ataaagacat cttaattggg cacgaaagag atgatgataa ttccgaagaa ggcttccaca ctattcattc aggaaggcat gaatatgcat tcagcttcga gcttccacag acaccactcg ctacctcatt cgaaggccga catggcagtg tgcgctattg ggtgaaagcc gaattgcaca ggccttggct actaccagta aaattaaaga aggaatttac agtctttgag catatagata tcaacactcc ttcattactg tcaccccaag caggcacaaa agaaaagaca ctctgttgct ggttctgtac ctcaggccca atatccttaa gtgccaaaat tgaaaggaag ggctataccc caggtgaatc aattcagata tttgctgaga ttgagaactg ctcttcccga atggtggtgc caaaggcagc catttaccaa acacaggcct tctatgccaa agggaaaatg aaggaagtaa aacagcttgt ggctaacttg cgtggggaat ccttatcatc tggaaagaca gagacgtgga atggcaagtt gctgaaaatt ccaccagttt ctccctctat cctcgactgt agtataatcc gcgtggaata ttcactaatg gtatatgtgg atattcctgg agctatggat ttatttctta atttgccact tgtcatcggt accattcctc tacatccatt tggtagcaga acctcaagtg taagcagtca gtgtagcatg aatatgaact ggctcagttt atcacttcct gaaagacctg aagcaccacc cagctatgca gaagtggtaa cagaggaaca aaggcggaac aatcttgcac cagtgagtgc ttgtgatgac tttgagagag cccttcaagg accactgttt gcatatatcc aggagtttcg attcttgcct ccacctcttt attcagagat tgatccaaat cctgatcagt cagcagatga tagaccatcc tgcccctctc gttga
Molecular Weight
46,395 Da
OMIM
612464
Vector
pENTR223.1 or pUC
Clone Sequence Report
Provided with product shipment
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of ARRDC3 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for ARRDC3. It may not necessarily be applicable to this product.

NCBI GI #
34193993
NCBI GeneID
57561
NCBI Accession #
BC015928
UniProt Secondary Accession #
Q9P2H1; A8K6T8
UniProt Related Accession #
Q96B67
NCBI Official Full Name
Homo sapiens arrestin domain containing 3, mRNA
NCBI Official Synonym Full Names
arrestin domain containing 3
NCBI Official Symbol
ARRDC3
NCBI Official Synonym Symbols
TLIMP
UniProt Protein Name
Arrestin domain-containing protein 3
UniProt Synonym Protein Names
TBP-2-like inducible membrane protein
Protein Family
Arrestin domain-containing protein
UniProt Gene Name
ARRDC3
UniProt Synonym Gene Names
KIAA1376; TLIMP
UniProt Entry Name
ARRD3_HUMAN
NCBI Protein Information
arrestin domain-containing protein 3

NCBI Summary for ARRDC3

This gene encodes a member of the arrestin family of proteins, which regulate G protein-mediated signaling. The encoded protein is thought to act as a regulator of breast cancer growth and progression by binding to a phosphorylated form of integrin beta4, a tumor-related antigen, targeting the integrin for internalization and degradation. [provided by RefSeq, Jul 2016]
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UniProt Comments for ARRDC3

ARRDC3: Belongs to the arrestin family.

Protein type: Unknown function

Chromosomal Location of Human Ortholog: 5q14.3

Cellular Component: endosome; plasma membrane

Molecular Function: beta-3 adrenergic receptor binding; protein binding

Biological Process: positive regulation of ubiquitin-protein ligase activity
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Research Articles on ARRDC3

1. Promoter hypermethylation is an important mechanism of the transcriptional inactivation of ARRDC3 in invasive ductal breast carcinoma.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Diseases associated with ARRDC3 cdna clone

 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >2 publications with ARRDC3 and Neoplasms
 Adenocarcinoma Antibodies  >1 publications with ARRDC3 and Adenocarcinoma
 Heart Defects, Congenital Antibodies  >1 publications with ARRDC3 and Heart Defects, Congenital
 Nervous System Diseases Antibodies  >1 publications with ARRDC3 and Nervous System Diseases
 Heart Diseases Antibodies  >1 publications with ARRDC3 and Heart Diseases
 Brain Diseases Antibodies  >1 publications with ARRDC3 and Brain Diseases
 Hypertension Antibodies  >1 publications with ARRDC3 and Hypertension
 Breast Neoplasms Antibodies  >1 publications with ARRDC3 and Breast Neoplasms

Organs/Tissues associated with ARRDC3 cdna clone

 Organ/Tissue Name  Pubmed Publications
 Skin Antibodies  >2 publications with ARRDC3 and Skin
 Blood Antibodies  >1 publications with ARRDC3 and Blood
 Nerve Antibodies  >1 publications with ARRDC3 and Nerve
 Heart Antibodies  >1 publications with ARRDC3 and Heart
 Vascular Antibodies  >1 publications with ARRDC3 and Vascular
 Prostate Antibodies  >1 publications with ARRDC3 and Prostate
 Eye Antibodies  >1 publications with ARRDC3 and Eye
 Connective Tissue Antibodies  >1 publications with ARRDC3 and Connective Tissue
 Uncharacterized Tissue Antibodies  >1 publications with ARRDC3 and Uncharacterized Tissue
 Brain Antibodies  >1 publications with ARRDC3 and Brain
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