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CCT7 cDNA Clone – Chaperonin Containing TCP1, Subunit 7 (Eta) (Human)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1276655

MBS1276655 is a cDNA clone targeting CCT7. More details

$400 / 0.01 mg Plasmid + 0.2 mL Glycerol-Stock +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
CCT7, cDNA Clone
Full Product Name
CCT7 cDNA Clone
Product Gene Name
CCT7 cdna clone
Sequence
atgatgccca caccagttat cctattgaaa gaggggactg atagctccca aggcatcccc cagcttgtga gtaacatcag tgcctgccag gtgattgctg aggctgtaag aactaccctg ggtccccgtg gcatggacaa gcttattgta gatggcagag gcaaagcaac aatttctaat gatggggcca caattctgaa acttcttgat gttgtccatc ctgcagcaaa gactttggta gacattgcca aatcccaaga tgctgaggtg ggtgatggca ccacctcagt gaccttgctg gctgcagagt ttctgaagca ggtgaaaccc tatgtggagg aaggtttaca cccccagatc atcattcgag ctttccgcac agccacccag ctggcagtta acaagatcaa agagattgct gtgaccgtga agaaggcaga taaagtggag cagaggaagc tgctggaaaa gtgtgccatg accgctctga gctccaagct gatctcccag cagaaagctt tctttgctaa gatggtggtg gatgcagtga tgatgctcga tgatttgctg cagcttaaaa tgattggaat caagaaggta cagggtggag ccctcgagga ttctcagctg gtagctggtg ttgcattcaa gaagactttc tcttacgctg ggtttgaaat gcaacccaaa aagtaccaca atcccaagat tgcccttttg aatgtcgagc tcgagttgaa agctgagaaa gacaatgctg agataagagt ccacacagtt gaggattatc aggcaattgt tgatgctgag tggaacattc tctatgacaa gttagagaag atccatcatt ctggagccaa agttgtcttg tccaaactcc ccattgggga tgtggccacc cagtactttg ctgacaggga catgttctgt gctggccgag tacctgagga ggatctgaag aggacaatga tggcctgtgg aggctcaatc cagaccagtg tgaatgctct gtcagcagat gtgctgggtc gatgccaggt gtttgaagag acccagattg gaggcgagag gtacaatttt tttactggct gccccaaggc caagacatgc accttcattc tccgtggcgg cgccgagcag tttatggagg agacagagcg gtccctgcat gatgccatca tgatcgtcag gagggccatc aagaatgatt cagtggtggc tggtggcggg gccattgaga tggaactctc caagtacctg cgggattact caaggactat tccaggaaaa cagcagctgt tgattggggc ttatgccaag gccttggaga ttatcccacg ccagctgtgt gacaatgctg gctttgatgc cacaaacatt ctcaacaagc tgcgggctcg gcatgcccag gggggtacat ggtatggagt agacatcaac aacgaggaca ttgctgacaa ctttgaagct ttcgtgtggg agccagctat ggtgcggatc aatgcgctga cagcagcctc tgaggctgcg tgcctgatcg tgtctgtaga tgaaaccatc aagaaccccc gctcgactgt ggatgctccc acagcagcag gccggggccg tggtcgtggc cgcccccact ga
Molecular Weight
50,352 Da
OMIM
605140
Vector
pENTR223.1
Clone Sequence Report
Provided with product shipment
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of CCT7 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for CCT7. It may not necessarily be applicable to this product.

NCBI GI #
17939553
NCBI GeneID
10574
NCBI Accession #
BC019296
UniProt Secondary Accession #
O14871; Q6FI26; A8K7E6; A8MWI8; B7WNW9; B7Z4T9; B7Z4Z7
UniProt Related Accession #
Q99832
NCBI Official Full Name
Homo sapiens chaperonin containing TCP1, subunit 7 (eta), mRNA
NCBI Official Synonym Full Names
chaperonin containing TCP1 subunit 7
NCBI Official Symbol
CCT7
NCBI Official Synonym Symbols
CCTH; CCTETA; NIP7-1; TCP1ETA
UniProt Protein Name
T-complex protein 1 subunit eta
UniProt Synonym Protein Names
CCT-eta; HIV-1 Nef-interacting protein
Protein Family
Probable T-complex protein
UniProt Gene Name
CCT7
UniProt Synonym Gene Names
CCTH; NIP7-1; TCP-1-eta
UniProt Entry Name
TCPH_HUMAN
NCBI Protein Information
T-complex protein 1 subunit eta

NCBI Summary for CCT7

This gene encodes a molecular chaperone that is a member of the chaperonin containing TCP1 complex (CCT), also known as the TCP1 ring complex (TRiC). This complex consists of two identical stacked rings, each containing eight different proteins. Unfolded polypeptides enter the central cavity of the complex and are folded in an ATP-dependent manner. The complex folds various proteins, including actin and tubulin. Alternative splicing results in multiple transcript variants. Related pseudogenes have been identified on chromosomes 5 and 6. [provided by RefSeq, Oct 2009]
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UniProt Comments for CCT7

CCT7: Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin. Belongs to the TCP-1 chaperonin family. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: Chaperone

Chromosomal Location of Human Ortholog: 2p13.2

Cellular Component: chaperonin-containing T-complex; cytoplasm; cytosol; microtubule

Molecular Function: protein binding

Biological Process: positive regulation of telomere maintenance via telomerase; protein folding; protein stabilization
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Research Articles on CCT7

1. the increased expression of CCT-eta appears to be a marker for latent and active Dupuytren's contracture and to be essential for the increased contractility exhibited by these fibroblasts

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with CCT7 cdna clone

 Products by Pathway  Pathway Diagram
 Association Of TriC/CCT With Target Proteins During Biosynthesis Pathway antibodies  Association Of TriC/CCT With Target Proteins During Biosynthesis Pathway Diagram
 Chaperonin-mediated Protein Folding Pathway antibodies  Chaperonin-mediated Protein Folding Pathway Diagram
 Cooperation Of Prefoldin And TriC/CCT In Actin And Tubulin Folding Pathway antibodies  Cooperation Of Prefoldin And TriC/CCT In Actin And Tubulin Folding Pathway Diagram
 Folding Of Actin By CCT/TriC Pathway antibodies  Folding Of Actin By CCT/TriC Pathway Diagram
 Formation Of Tubulin Folding Intermediates By CCT/TriC Pathway antibodies  Formation Of Tubulin Folding Intermediates By CCT/TriC Pathway Diagram
 Metabolism Of Proteins Pathway antibodies  Metabolism Of Proteins Pathway Diagram
 Prefoldin Mediated Transfer Of Substrate To CCT/TriC Pathway antibodies  Prefoldin Mediated Transfer Of Substrate To CCT/TriC Pathway Diagram
 Protein Folding Pathway antibodies  Protein Folding Pathway Diagram

Diseases associated with CCT7 cdna clone

 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >18 publications with CCT7 and Neoplasms
 Disease Models, Animal Antibodies  >6 publications with CCT7 and Disease Models, Animal
 Adenocarcinoma Antibodies  >6 publications with CCT7 and Adenocarcinoma
 Neoplasms, Experimental Antibodies  >5 publications with CCT7 and Neoplasms, Experimental
 Liver Neoplasms Antibodies  >3 publications with CCT7 and Liver Neoplasms
 Liver Diseases Antibodies  >3 publications with CCT7 and Liver Diseases
 Carcinoma, Hepatocellular Antibodies  >3 publications with CCT7 and Carcinoma, Hepatocellular
 Disease Progression Antibodies  >3 publications with CCT7 and Disease Progression
 Necrosis Antibodies  >2 publications with CCT7 and Necrosis
 Atrophy Antibodies  >2 publications with CCT7 and Atrophy

Organs/Tissues associated with CCT7 cdna clone

 Organ/Tissue Name  Pubmed Publications
 Testis Antibodies  >29 publications with CCT7 and Testis
 Nerve Antibodies  >21 publications with CCT7 and Nerve
 Blood Antibodies  >21 publications with CCT7 and Blood
 Brain Antibodies  >20 publications with CCT7 and Brain
 Muscle Antibodies  >11 publications with CCT7 and Muscle
 Skin Antibodies  >8 publications with CCT7 and Skin
 Embryonic Tissue Antibodies  >6 publications with CCT7 and Embryonic Tissue
 Eye Antibodies  >6 publications with CCT7 and Eye
 Liver Antibodies  >5 publications with CCT7 and Liver
 Connective Tissue Antibodies  >5 publications with CCT7 and Connective Tissue
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