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CD200 cDNA Clone – CD200 Molecule (Human)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1273930

MBS1273930 is a cDNA clone targeting CD200. More details

$235 / 0.01 mg Plasmid + 0.2 mL Glycerol-Stock +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
CD200, cDNA Clone
Full Product Name
CD200 cDNA Clone
Product Gene Name
CD200 cdna clone
Sequence
atggagaggc tggtgatcag gatgcccttc tgtcatctgt ctacctacag cctggtttgg gtcatggcag cagtggtgct gtgcacagca caagtgcaag tggtgaccca ggatgaaaga gagcagctgt acacacctgc ttccttaaaa tgctctctgc aaaatgccca ggaagccctc attgtgacat ggcagaaaaa gaaagctgta agcccagaaa acatggtcac cttcagcgag aaccatgggg tggtgatcca gcctgcctat aaggacaaga taaacattac ccagctggga ctccaaaact caaccatcac cttctggaat atcaccctgg aggatgaagg gtgttacatg tgtctcttca atacctttgg ttttgggaag atctcaggaa cggcctgcct caccgtctat gtacagccca tagtatccct tcactacaaa ttctctgaag accacctaaa tatcacttgc tctgccactg cccgcccagc ccccatggtc ttctggaagg tccctcggtc agggattgaa aatagtacag tgactctgtc tcacccaaat gggaccacgt ctgttaccag catcctccat atcaaagacc ctaagaatca ggtggggaag gaggtgatct gccaggtgct gcacctgggg actgtgaccg actttaagca aaccgtcaac aaaggctatt ggttttcagt tccgctattg ctaagcattg tttccctggt aattcttctc gtcctaatct caatcttact gtactggaaa cgtcaccgga atcaggaccg agagccctaa
Molecular Weight
32,975 Da
OMIM
155970
Vector
pENTR223.1 or pUC
Clone Sequence Report
Provided with product shipment
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of CD200 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for CD200. It may not necessarily be applicable to this product.

NCBI GI #
18490920
NCBI GeneID
4345
NCBI Accession #
BC022522
UniProt Secondary Accession #
Q6J2Q6; Q6PIQ4; Q8TB85; Q9H3J3; B3KQI1; B4DLW9; D3DN65
UniProt Related Accession #
P41217
NCBI Official Full Name
Homo sapiens CD200 molecule, mRNA
NCBI Official Synonym Full Names
CD200 molecule
NCBI Official Symbol
CD200
NCBI Official Synonym Symbols
MRC; MOX1; MOX2; OX-2
UniProt Protein Name
OX-2 membrane glycoprotein
UniProt Synonym Protein Names
CD_antigen: CD200
Protein Family
OX-2 membrane glycoprotein
UniProt Gene Name
CD200
UniProt Synonym Gene Names
MOX1; MOX2
UniProt Entry Name
OX2G_HUMAN
NCBI Protein Information
OX-2 membrane glycoprotein

NCBI Summary for CD200

This gene encodes a type I membrane glycoprotein containing two extracellular immunoglobulin domains, a transmembrane and a cytoplasmic domain. This gene is expressed by various cell types, including B cells, a subset of T cells, thymocytes, endothelial cells, and neurons. The encoded protein plays an important role in immunosuppression and regulation of anti-tumor activity. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Jan 2016]
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UniProt Comments for CD200

CD200: Costimulates T-cell proliferation. May regulate myeloid cell activity in a variety of tissues. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: 3q13.2

Cellular Component: cell-cell adherens junction; integral to plasma membrane; plasma membrane

Molecular Function: cell adhesion molecule binding; protein binding; protein homodimerization activity; receptor activity; receptor binding

Biological Process: cell recognition; heterophilic cell adhesion; homophilic cell adhesion; regulation of immune response
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Research Articles on CD200

1. CD200 signaling may play a key role in regulating macrophage polarization toward anti-inflammatory phenotypes

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with CD200 cdna clone

 Products by Pathway  Pathway Diagram
 Adaptive Immune System Pathway antibodies  Adaptive Immune System Pathway Diagram
 Immune System Pathway antibodies  Immune System Pathway Diagram
 Immunoregulatory Interactions Between A Lymphoid And A Non-Lymphoid Cell Pathway antibodies  Immunoregulatory Interactions Between A Lymphoid And A Non-Lymphoid Cell Pathway Diagram

Diseases associated with CD200 cdna clone

 Disease Name  Pubmed Publications
 Inflammation Antibodies  >67 publications with CD200 and Inflammation
 Neoplasms Antibodies  >66 publications with CD200 and Neoplasms
 Necrosis Antibodies  >33 publications with CD200 and Necrosis
 Disease Models, Animal Antibodies  >30 publications with CD200 and Disease Models, Animal
 Carcinoma Antibodies  >11 publications with CD200 and Carcinoma
 Breast Neoplasms Antibodies  >8 publications with CD200 and Breast Neoplasms
 Cardiovascular Diseases Antibodies  >8 publications with CD200 and Cardiovascular Diseases
 Skin Neoplasms Antibodies  >7 publications with CD200 and Skin Neoplasms
 Fibrosis Antibodies  >4 publications with CD200 and Fibrosis
 Carcinoma, Squamous Cell Antibodies  >4 publications with CD200 and Carcinoma, Squamous Cell

Organs/Tissues associated with CD200 cdna clone

 Organ/Tissue Name  Pubmed Publications
 Blood Antibodies  >135 publications with CD200 and Blood
 Brain Antibodies  >59 publications with CD200 and Brain
 Skin Antibodies  >56 publications with CD200 and Skin
 Bone Marrow Antibodies  >32 publications with CD200 and Bone Marrow
 Spleen Antibodies  >26 publications with CD200 and Spleen
 Lymph Node Antibodies  >23 publications with CD200 and Lymph Node
 Vascular Antibodies  >16 publications with CD200 and Vascular
 Lung Antibodies  >16 publications with CD200 and Lung
 Embryonic Tissue Antibodies  >13 publications with CD200 and Embryonic Tissue
 Eye Antibodies  >11 publications with CD200 and Eye
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