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CYP2A7 cDNA Clone – Cytochrome P450, Family 2, Subfamily A, Polypeptide 7 (Human)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1273569

MBS1273569 is a cDNA clone targeting CYP2A7. More details

$235 / 0.01 mg Plasmid + 0.2 mL Glycerol-Stock +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
CYP2A7, cDNA Clone
Full Product Name
CYP2A7 cDNA Clone
Product Gene Name
CYP2A7 cdna clone
Sequence
atgctggcct cagggctgct tctggtggcc ttgctggcct gcctgactgt gatggtcttg atgtctgtct ggcagcagag gaagagcagg gggaagctgc ctccgggacc caccccactg cccttcattg gaaactacct ccagctgaac acagagcaca tatgtgactc catcatgaag ttcagtgagt gctatggccc cgtgttcacc attcacttgg ggccccggcg ggccgtggtg ctgtgtggac atgatgccgt cagggaggct ctggtggacc aggctgagga gttcagcggg cgaggcgagc aagccacctt cgactgggtc ttcaaaggct atggcgtggc gttcagcaac ggggagcgcg ccaagcagct cctgcgcttt gccatcgcca ccctgaggga cttcggggtg ggcaagcgag gcatcgagga gcgcatccag gaggagtcgg gcttcctcat cgaggccatc cggagcacgc acggcgccaa tatcgatccc accttcttcc tgagccgcac agtctccaat gtcatcagct ccattgtctt tggggaccgc tttgactatg aggacaaaga gttcctgtca ctgctgagcg tgatgctagg aatcttccag ttcacgtcaa cctccacggg gcagctctat gagatgttct cttcggtgat gaaacacctg ccaggaccac agcaacaggc ctttaagttg ctgcaagggc tggaggactt catagccaag aaggtggagc acaaccagcg cacgctggat cccaattccc cacgggactt catcgactcc tttctcatcc gcatgcagga ggaggagaag aaccccaaca cggagttcta cttgaagaac ctgatgatga gcacgttgaa cctcttcatt gcaggcaccg agacggtcag caccaccctg cgctatggct tcttgctgct catgaagcac ccagaggtgg aggccaaggt ccatgaggag attgacagag tgatcggcaa gaaccggcag cccaagtttg aggaccgggc caagatgccc tacatggagg cagtgatcca cgagatccaa agatttggag acgtgatccc catgagtttg gcccgcaggg ttaaaaagga caccaagttt cgggattttt tcctccctaa gggcaccgaa gtgttcccta tgctgggctc cgtgctgaga gaccccagct tcttctccaa ccctcaggac ttcaatcccc agcatttcct ggatgacaag gggcagttta agaagagtga tgcttttgtg cccttttcca tcggaaagcg gtactgtttc ggagaaggcc tggccagaat ggagctcttt ctcttcttca ccaccgtcat gcagaacttc cgcctcaagt cctcccagtc acctaaggac attgacgtgt cccccaaaca cgtgggcttt gccacgatcc cacgaaacta caccatgagc ttcctgcccc gctga
Molecular Weight
56,425 Da
OMIM
608054
Vector
pENTR223.1 or pUC
Clone Sequence Report
Provided with product shipment
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of CYP2A7 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for CYP2A7. It may not necessarily be applicable to this product.

NCBI GI #
109658963
NCBI GeneID
1549
NCBI Accession #
BC117165
UniProt Secondary Accession #
Q13121
UniProt Related Accession #
P20853
NCBI Official Full Name
Homo sapiens cytochrome P450, family 2, subfamily A, polypeptide 7, mRNA
NCBI Official Synonym Full Names
cytochrome P450 family 2 subfamily A member 7
NCBI Official Symbol
CYP2A7
NCBI Official Synonym Symbols
CPA7; CPAD; CYP2A; CYPIIA7; P450-IIA4
UniProt Protein Name
Cytochrome P450 2A7
UniProt Synonym Protein Names
CYPIIA7; Cytochrome P450 IIA4
Protein Family
Cytochrome
UniProt Gene Name
CYP2A7
UniProt Entry Name
CP2A7_HUMAN
NCBI Protein Information
cytochrome P450 2A7

NCBI Summary for CYP2A7

This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum; its substrate has not yet been determined. This gene, which produces two transcript variants, is part of a large cluster of cytochrome P450 genes from the CYP2A, CYP2B and CYP2F subfamilies on chromosome 19q. [provided by RefSeq, Jul 2008]
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UniProt Comments for CYP2A7

CYP2A7: Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It oxidizes a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. Belongs to the cytochrome P450 family.

Protein type: Cofactor and Vitamin Metabolism - retinol; Xenobiotic Metabolism - drug metabolism - cytochrome P450; Secondary Metabolites Metabolism - caffeine; EC 1.14.14.1; Endoplasmic reticulum; Oxidoreductase; Xenobiotic Metabolism - drug metabolism - other enzymes

Chromosomal Location of Human Ortholog: 19q13.2

Molecular Function: arachidonic acid epoxygenase activity; oxygen binding; steroid hydroxylase activity

Biological Process: epoxygenase P450 pathway
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Research Articles on CYP2A7

1. CYP2A7 affects CYP2A6 expression by competing for miR-126* binding.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with CYP2A7 cdna clone

 Products by Pathway  Pathway Diagram
 Biological Oxidations Pathway antibodies  Biological Oxidations Pathway Diagram
 CYP2E1 Reactions Pathway antibodies  CYP2E1 Reactions Pathway Diagram
 Caffeine Metabolism Pathway antibodies  Caffeine Metabolism Pathway Diagram
 Caffeine Metabolism Pathway antibodies  Caffeine Metabolism Pathway Diagram
 Chemical Carcinogenesis Pathway antibodies  Chemical Carcinogenesis Pathway Diagram
 Chemical Carcinogenesis Pathway antibodies  Chemical Carcinogenesis Pathway Diagram
 Cytochrome P450 - Arranged By Substrate Type Pathway antibodies  Cytochrome P450 - Arranged By Substrate Type Pathway Diagram
 Drug Metabolism - Cytochrome P450 Pathway antibodies  Drug Metabolism - Cytochrome P450 Pathway Diagram
 Drug Metabolism - Cytochrome P450 Pathway antibodies  Drug Metabolism - Cytochrome P450 Pathway Diagram
 Drug Metabolism - Other Enzymes Pathway antibodies  Drug Metabolism - Other Enzymes Pathway Diagram

Diseases associated with CYP2A7 cdna clone

 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >9 publications with CYP2A7 and Neoplasms
 Liver Neoplasms Antibodies  >4 publications with CYP2A7 and Liver Neoplasms
 Liver Diseases Antibodies  >4 publications with CYP2A7 and Liver Diseases
 Carcinoma Antibodies  >4 publications with CYP2A7 and Carcinoma
 Carcinoma, Hepatocellular Antibodies  >2 publications with CYP2A7 and Carcinoma, Hepatocellular
 Lung Neoplasms Antibodies  >2 publications with CYP2A7 and Lung Neoplasms
 Adenocarcinoma Antibodies  >2 publications with CYP2A7 and Adenocarcinoma
 Mental Disorders Antibodies  >1 publications with CYP2A7 and Mental Disorders
 Breast Neoplasms Antibodies  >1 publications with CYP2A7 and Breast Neoplasms
 Carcinoma, Squamous Cell Antibodies  >1 publications with CYP2A7 and Carcinoma, Squamous Cell

Organs/Tissues associated with CYP2A7 cdna clone

 Organ/Tissue Name  Pubmed Publications
 Liver Antibodies  >13 publications with CYP2A7 and Liver
 Mammary Gland Antibodies  >1 publications with CYP2A7 and Mammary Gland
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