Human DDX21 cDNA Clone Expression Plasmid – Cat# MBS1278423

DDX21 cDNA Clone – DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 21 (Human)

Name: DDX21 cDNA Clone; Human; MyBioSource
Brand: MyBioSource
SKU: MBS1278423
Price: 235 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1278423

MBS1278423 is a cDNA clone targeting DDX21. More details

$235 / 0.01 mg Plasmid + 0.2 mL Glycerol-Stock +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

DDX21, cDNA Clone

Full Product Name

DDX21 cDNA Clone

Product Gene Name

DDX21 cdna clone

Sequence

atgccgggaa aactccgtag tgacgctggt ttggaatcag acaccgcaat gaaaaaaggg gagacactgc gaaagcaaac cgaggagaaa gagaaaaaag agaagccaaa atctgataag actgaagaga tagcagaaga ggaagaaact gttttcccca aagctaaaca agttaaaaag aaagcagagc cttctgaagt tgacatgaat tctcctaaat ccaaaaaggc aaaaaagaaa gaggagccat ctcaaaatga catttctcct aaaaccaaaa gtttgagaaa gaaaaaggag cccattgaaa agaaagtggt ttcttctaaa accaaaaaag tgacaaaaaa tgaggagcct tctgaggaag aaatagatgc tcctaagccc aagaagatga agaaagaaaa ggaaatgaat ggagaaacta gagagaaaag ccccaaactg aagaatggat ttcctcatcc tgaaccggac tgtaacccca gtgaagctgc cagtgaagaa agtaacagtg agatagagca ggaaatacct gtggaacaaa aagaaggcgc tttctctaat tttcccatat ctgaagaaac tattaaactt ctcaaaggcc gaggagtgac cttcctattt cctatacaag caaagacatt ccatcatgtt tacagcggga aggacttaat tgcacaggca cggacaggaa ctgggaagac attctccttt gccatccctt tgattgagaa acttcatggg gaactgcaag acaggaagag aggccgtgcc cctcaggtac tggttcttgc acctacaaga gagttggcaa atcaagtaag caaagacttc agtgacatca caaaaaagct gtcagtggct tgtttttatg gtggaactcc ctatggaggt caatttgaac gcatgaggaa tgggattgat atcctggttg gaacaccagg tcgtatcaaa gaccacatac agaatggcaa actagatctc accaaactta agcatgttgt cctggatgaa gtggaccaga tgttggatat gggatttgct gatcaagtgg aagagatttt aagtgtggca tacaagaaag attctgaaga caatccccaa acattgcttt tttctgcaac ttgccctcat tgggtattta atgttgccaa gaaatacatg aaatctacat atgaacaggt ggacctgatt ggtaaaaaga ctcagaaaac ggcaataact gtggagcatc tggctattaa gtgccactgg actcagaggg cagcagttat tggggatgtc atccgagtat atagtggtca tcaaggacgc actatcatct tttgtgaaac caagaaagaa gcccaggagc tgtcccagaa ttcagctata aagcaggatg ctcagtcctt gcatggagac attccacaga agcaaaggga aatcaccctg aaaggtttta gaaatggtag ttttggagtt ttggtggcaa ccaatgttgc tgcacgtggg ttagacatcc ctgaggttga tttggttata caaagctctc caccaaagga tgtagagtcc tacattcatc gatccgggcg gacaggcaga gctggaagga cgggggtgtg catctgcttt tatcagcaca aggaagaata tcagttagta caagtggagc aaaaagcggg aattaagttc aaacgaatag gtgttccttc tgcaacagaa ataataaaag cttccagcaa agatgccatc aggcttttgg attccgtgcc tcccactgcc attagtcact tcaaacaatc agctgagaag ctgatagagg agaagggagc tgtggaagct ctggcagcag cactggccca tatttcaggt gccacgtccg tagaccagcg ctccttgatc aactcaaatg tgggttttgt gaccatgatc ttgcagtgct caattgaaat gccaaatatt agttatgctt ggaaagaact taaagagcag ctgggcgagg agattgattc caaagtgaag ggaatggttt ttctcaaagg aaagctgggt gtttgctttg atgtacctac cgcatcagta acagaaatac aggagaaatg gcatgattca cgacgctggc agctctctgt ggccacagag caaccagaac tggaaggacc acgggaagga tatggaggct tcaggggaca gcgggaaggc agtcgaggct tcaggggaca gcgggacgga aacagaagat tcagaggaca gcgggaaggc agtagaggcc cgagaggaca gcgatcagga ggtggcaaca aaagtaacag atcccaaaac aaaggccaga agcggagttt cagtaaagca tttggtcaat aa

Molecular Weight

79,657 Da

OMIM

606357

Vector

pENTR223.1

Clone Sequence Report

Provided with product shipment

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of DDX21 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for DDX21. It may not necessarily be applicable to this product.

NCBI GI #

33873806

NCBI GeneID

9188

NCBI Accession #

BC008071

UniProt Secondary Accession #

Q13436; Q5VX41; Q68D35; B2RDL0

UniProt Related Accession #

Q9NR30

NCBI Official Full Name

Homo sapiens DEAD (Asp-Glu-Ala-Asp) box polypeptide 21, mRNA

NCBI Official Synonym Full Names

DEAD-box helicase 21

NCBI Official Symbol

DDX21

NCBI Official Synonym Symbols

GUA; GURDB; RH-II/GU; RH-II/GuA

UniProt Protein Name

Nucleolar RNA helicase 2

UniProt Synonym Protein Names

DEAD box protein 21; Gu-alpha; Nucleolar RNA helicase Gu; Nucleolar RNA helicase II; RH II/Gu

Protein Family

Nucleolar RNA helicase

UniProt Gene Name

DDX21

UniProt Entry Name

DDX21_HUMAN

NCBI Protein Information

nucleolar RNA helicase 2

NCBI Summary for DDX21

DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp (DEAD), are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly. Based on their distribution patterns, some members of this family are believed to be involved in embryogenesis, spermatogenesis, and cellular growth and division. This gene encodes a DEAD box protein, which is an antigen recognized by autoimmune antibodies from a patient with watermelon stomach disease. This protein unwinds double-stranded RNA, folds single-stranded RNA, and may play important roles in ribosomal RNA biogenesis, RNA editing, RNA transport, and general transcription. [provided by RefSeq, Jul 2008]

UniProt Comments for DDX21

DDX21: a protein of the DEAD box helicase family. Unwinds double-stranded RNA, folds single-stranded RNA, and may play important roles in ribosomal RNA biogenesis, RNA editing, RNA transport, and general transcription. DEAD box proteins, characterized by the conserved motif Asp-Glu-Ala-Asp, are putative RNA helicases. They are implicated in a number of cellular processes involving alteration of RNA secondary structure such as translation initiation, nuclear and mitochondrial splicing, and ribosome and spliceosome assembly.

Protein type: Nucleolus; Helicase; RNA-binding; RNA processing; EC 3.6.4.13

Chromosomal Location of Human Ortholog: 10q21

Cellular Component: membrane; nucleolus; nucleoplasm; nucleus

Molecular Function: ATP-dependent RNA helicase activity; protein binding; rRNA binding; snoRNA binding

Biological Process: osteoblast differentiation; positive regulation of gene expression, epigenetic; RNA secondary structure unwinding; transcription from RNA polymerase II promoter

Research Articles on DDX21

1. DDX21 expression in breast cancer cells can promote AP-1 activity and rRNA processing, and thus, promote tumorigenesis by two independent mechanisms.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

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Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Diseases associated with DDX21 cdna clone

Disease Name	Pubmed Publications
Neoplasms, Experimental Antibodies	>2 publications with DDX21 and Neoplasms, Experimental
Breast Neoplasms Antibodies	>1 publications with DDX21 and Breast Neoplasms

Organs/Tissues associated with DDX21 cdna clone

Organ/Tissue Name	Pubmed Publications
Kidney Antibodies	>2 publications with DDX21 and Kidney
Lymph Antibodies	>1 publications with DDX21 and Lymph
Lymph Node Antibodies	>1 publications with DDX21 and Lymph Node