Human ECH1 cDNA Clone Expression Plasmid – Cat# MBS1270901

ECH1 cDNA Clone – Enoyl Coenzyme A Hydratase 1, Peroxisomal (Human)

Name: ECH1 cDNA Clone; Human; MyBioSource
Brand: MyBioSource
SKU: MBS1270901
Price: 235 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1270901

MBS1270901 is a cDNA clone targeting ECH1. More details

$235 / 0.01 mg Plasmid + 0.2 mL Glycerol-Stock +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

ECH1, cDNA Clone

Full Product Name

ECH1 cDNA Clone

Product Gene Name

ECH1 cdna clone

Sequence

atggcggcgg ggatagtggc ttctcgcaga ctccgcgacc tactgacccg gcgactgaca ggctccaact acccgggact cagtattagc cttcgcctca ctggctcctc tgcacaagag gaggcttccg gagtagccct cggtgaagcc ccagaccaca gctatgagtc ccttcgtgtg acgtctgcgc agaaacatgt tctgcatgtc cagctcaacc ggcccaacaa gaggaatgcc atgaacaagg tcttctggag agagatggta gagtgcttca acaagatttc gagagacgct gactgtcggg cggtggtgat ctctggtgca ggaaaaatgt tcactgcagg tattgacctg atggacatgg cttcagacat cctgcagccc aaaggagatg atgtggcccg gatcagctgg tacctccgtg acatcatcac tcgataccag gagaccttca acgtcatcga gaggtgcccc aagcccgtga ttgctgccgt ccatgggggc tgcattggcg gaggtgtgga ccttgtcacc gcctgtgaca tccggtactg tgcccaggat gctttcttcc aggtgaagga ggtggacgtg ggtttggctg ccgatgtagg aacactgcag cgcctgccca aggtcatcgg gaaccagagc ctggtcaacg agctggcctt caccgcccgc aagatgatgg ctgacgaggc cctgggcagt gggctggtca gccgggtgtt cccagacaaa gaggtcatgc tggatgctgc cttagcgctg gcggccgaga tttccagcaa gagccccgtg gcggtgcaga gcaccaaggt caacctgctg tattcccgcg accattcggt ggccgagagc ctcaactacg tggcgtcctg gaacatgagc atgctgcaga cccaagacct cgtgaagtcg gtccaggcca cgactgagaa caaggaactg aaaaccgtca ccttctccaa gctctga

Molecular Weight

35,816 Da

OMIM

600696

Vector

pENTR223.1 or pUC

Clone Sequence Report

Provided with product shipment

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of ECH1 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for ECH1. It may not necessarily be applicable to this product.

NCBI GI #

40226519

NCBI GeneID

1891

NCBI Accession #

BC011792

UniProt Secondary Accession #

Q8WVX0; Q96EZ9; A8K745

UniProt Related Accession #

Q13011

NCBI Official Full Name

Homo sapiens enoyl Coenzyme A hydratase 1, peroxisomal, mRNA

NCBI Official Synonym Full Names

enoyl-CoA hydratase 1

NCBI Official Symbol

ECH1

NCBI Official Synonym Symbols

HPXEL

UniProt Protein Name

Delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial

UniProt Gene Name

ECH1

UniProt Entry Name

ECH1_HUMAN

NCBI Protein Information

delta(3,5)-Delta(2,4)-dienoyl-CoA isomerase, mitochondrial

NCBI Summary for ECH1

This gene encodes a member of the hydratase/isomerase superfamily. The gene product shows high sequence similarity to enoyl-coenzyme A (CoA) hydratases of several species, particularly within a conserved domain characteristic of these proteins. The encoded protein, which contains a C-terminal peroxisomal targeting sequence, localizes to the peroxisome. The rat ortholog, which localizes to the matrix of both the peroxisome and mitochondria, can isomerize 3-trans,5-cis-dienoyl-CoA to 2-trans,4-trans-dienoyl-CoA, indicating that it is a delta3,5-delta2,4-dienoyl-CoA isomerase. This enzyme functions in the auxiliary step of the fatty acid beta-oxidation pathway. Expression of the rat gene is induced by peroxisome proliferators. [provided by RefSeq, Jul 2008]

UniProt Comments for ECH1

ECH1: Isomerization of 3-trans,5-cis-dienoyl-CoA to 2-trans,4- trans-dienoyl-CoA. Belongs to the enoyl-CoA hydratase/isomerase family.

Protein type: EC 5.3.3.-; Amino Acid Metabolism - tyrosine; Isomerase; Mitochondrial

Chromosomal Location of Human Ortholog: 19q13.1

Cellular Component: membrane; mitochondrion

Molecular Function: protein binding; receptor binding

Biological Process: fatty acid catabolic process

Research Articles on ECH1

1. Observational study of gene-disease association. (HuGE Navigator)

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with ECH1 cdna clone

Products by Pathway	Pathway Diagram
Fatty Acid Biosynthesis Pathway antibodies	Fatty Acid Biosynthesis Pathway Diagram
Peroxisome Pathway antibodies	Peroxisome Pathway Diagram
Peroxisome Pathway antibodies	Peroxisome Pathway Diagram

Diseases associated with ECH1 cdna clone

Disease Name	Pubmed Publications
Neoplasms Antibodies	>9 publications with ECH1 and Neoplasms
Liver Neoplasms Antibodies	>4 publications with ECH1 and Liver Neoplasms
Liver Diseases Antibodies	>4 publications with ECH1 and Liver Diseases
Liver Neoplasms, Experimental Antibodies	>3 publications with ECH1 and Liver Neoplasms, Experimental
Neoplasms, Experimental Antibodies	>3 publications with ECH1 and Neoplasms, Experimental
Cardiovascular Diseases Antibodies	>2 publications with ECH1 and Cardiovascular Diseases
Atherosclerosis Antibodies	>2 publications with ECH1 and Atherosclerosis
Hypertension Antibodies	>1 publications with ECH1 and Hypertension
Drug Toxicity Antibodies	>1 publications with ECH1 and Drug Toxicity
Carcinoma, Hepatocellular Antibodies	>1 publications with ECH1 and Carcinoma, Hepatocellular

Organs/Tissues associated with ECH1 cdna clone

Organ/Tissue Name	Pubmed Publications
Liver Antibodies	>6 publications with ECH1 and Liver
Muscle Antibodies	>4 publications with ECH1 and Muscle
Lymph Antibodies	>3 publications with ECH1 and Lymph
Lymph Node Antibodies	>3 publications with ECH1 and Lymph Node
Blood Antibodies	>3 publications with ECH1 and Blood
Heart Antibodies	>2 publications with ECH1 and Heart
Stomach Antibodies	>2 publications with ECH1 and Stomach
Bone Antibodies	>2 publications with ECH1 and Bone
Vascular Antibodies	>1 publications with ECH1 and Vascular
Lung Antibodies	>1 publications with ECH1 and Lung