Human EIF3M cDNA Clone Expression Plasmid – Cat# MBS1275438

EIF3M cDNA Clone – Eukaryotic Translation Initiation Factor 3, Subunit M (Human)

Name: EIF3M cDNA Clone; Human; MyBioSource
Brand: MyBioSource
SKU: MBS1275438
Price: 235 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1275438

MBS1275438 is a cDNA clone targeting EIF3M. More details

$235 / 0.01 mg Plasmid + 0.2 mL Glycerol-Stock +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

EIF3M, cDNA Clone

Full Product Name

EIF3M cDNA Clone

Product Gene Name

EIF3M cdna clone

Sequence

atgagcgtcc cggccttcat cgacatcagt gaagaagatc aggctgctga gcttcgtgct tatctgaaat ctaaaggagc tgagatttca gaagagaact cggaaggtgg acttcatgtt gatttagctc aaattattga agcctgtgat gtgtgtctga aggaggatga taaagatgtt gaaagtgtga tgaacagtgt ggtatcccta ctcttgatcc tggaaccaga caagcaagaa gctttgattg aaagcctatg tgaaaagctg gtcaaatttc gcgaaggtga acgcccgtct ctgagactgc agttgttaag caaccttttc cacgggatgg ataagaatac tcctgtaaga tacacagtgt attgcagcct tattaaagtg gcagcatctt gtggggccat ccagtacatc ccaactgagc tggatcaagt tagaaaatgg atttctgact ggaatctcac cactgaaaaa aagcacaccc ttttaagact actttatgag gcacttgtgg attgtaagaa gagtgatgct gcttcaaaag tcatggtgga attgctcgga agttacacag aggacaatgc ttcccaggct cgagttgatg cccacaggtg tattgtacga gcattgaaag atccaaatgc atttcttttt gaccaccttc ttactttaaa accagtcaag tttttggaag gcgagcttat tcatgatctt ttaaccattt ttgtgagtgc taaattggca tcatatgtca agttttatca gaataataaa gacttcattg attcacttgg cctgttacat gaacagaata tggcaaaaat gagactactt acttttatgg gaatggcagt agaaaataag gaaatttctt ttgacacaat gcagcaagaa cttcagattg gagctgatga tgttgaagca tttgttattg acgccgtaag aactaaaatg gtctactgca aaattgatca gacccagaga aaagtagttg tcagtcatag cacacatcgg acatttggaa aacagcagtg gcaacaactg tatgacacac ttaatgcctg gaaacaaaat ctgaacaaag tgaaaaacag ccttttgagt ctttctgata cctga

Molecular Weight

27,865 Da

OMIM

609641

Vector

pENTR223.1

Clone Sequence Report

Provided with product shipment

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of EIF3M cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for EIF3M. It may not necessarily be applicable to this product.

NCBI GI #

40225887

NCBI GeneID

10480

NCBI Accession #

BC019103

UniProt Secondary Accession #

O60735; Q2F836; Q53HL6; Q9BXW1; A8K7X4; B4E2Q4

UniProt Related Accession #

Q7L2H7

NCBI Official Full Name

Homo sapiens eukaryotic translation initiation factor 3, subunit M, mRNA

NCBI Official Synonym Full Names

eukaryotic translation initiation factor 3 subunit M

NCBI Official Symbol

EIF3M

NCBI Official Synonym Symbols

B5; GA17; PCID1; TANGO7; hfl-B5

UniProt Protein Name

Eukaryotic translation initiation factor 3 subunit M

UniProt Synonym Protein Names

Fetal lung protein B5; hFL-B5; PCI domain-containing protein 1

Protein Family

Eukaryotic translation initiation factor

UniProt Gene Name

EIF3M

UniProt Synonym Gene Names

eIF3m; hFL-B5

UniProt Entry Name

EIF3M_HUMAN

NCBI Protein Information

eukaryotic translation initiation factor 3 subunit M

NCBI Summary for EIF3M

This gene encodes a protein that is part of the eurkaryotic translation initiation factor 3 complete (eIF-3) required for protein synthesis. Elevated levels of the encoded protein are present in cancer cell lines. Inactivation of the encoded protein has been shown to interfere with translation of herpes virus mRNAs by preventing the association of mRNAs with the ribosomes. A pseudogene of this gene is located on the X chromosome. [provided by RefSeq, Dec 2011]

UniProt Comments for EIF3M

EIF3M: Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is required for several steps in the initiation of protein synthesis. The eIF-3 complex associates with the 40S ribosome and facilitates the recruitment of eIF-1, eIF-1A, eIF-2:GTP:methionyl-tRNAi and eIF-5 to form the 43S preinitiation complex (43S PIC). The eIF-3 complex stimulates mRNA recruitment to the 43S PIC and scanning of the mRNA for AUG recognition. The eIF-3 complex is also required for disassembly and recycling of post-termination ribosomal complexes and subsequently prevents premature joining of the 40S and 60S ribosomal subunits prior to initiation. May favor virus entry in case of infection with herpes simplex virus 1 (HSV1) or herpes simplex virus 2 (HSV2). Belongs to the eIF-3 subunit M family.

Protein type: Translation initiation

Chromosomal Location of Human Ortholog: 11p13

Cellular Component: cytosol; eukaryotic translation initiation factor 3 complex

Molecular Function: protein binding; translation initiation factor activity

Biological Process: translational initiation

Research Articles on EIF3M

1. POLR2J interacts with three different subunits of eIF3, eIF3a, eIF3i, and eIF3m.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Diseases associated with EIF3M cdna clone

Disease Name	Pubmed Publications
Neoplasms Antibodies	>3 publications with EIF3M and Neoplasms
Cell Transformation, Neoplastic Antibodies	>2 publications with EIF3M and Cell Transformation, Neoplastic

Organs/Tissues associated with EIF3M cdna clone

Organ/Tissue Name	Pubmed Publications
Uncharacterized Tissue Antibodies	>1 publications with EIF3M and Uncharacterized Tissue
Lung Antibodies	>1 publications with EIF3M and Lung