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IL22RA1 cDNA Clone – Interleukin 22 Receptor, Alpha 1 (Human)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1274937

MBS1274937 is a cDNA clone targeting IL22RA1. More details

$400 / 0.01 mg Plasmid + 0.2 mL Glycerol-Stock +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
IL22RA1, cDNA Clone
Full Product Name
IL22RA1 cDNA Clone
Product Gene Name
IL22RA1 cdna clone
Sequence
atgaggacgc tgctgaccat cttgactgtg ggatccctgg ctgctcacgc ccctgaggac ccctcggatc tgctccagca cgtgaaattc cagtccagca actttgaaaa catcctgacg tgggacagcg ggccggaggg caccccagac acggtctaca gcatcgagta taagacgtac ggagagaggg actgggtggc aaagaagggc tgtcagcgga tcacccggaa gtcctgcaac ctgacggtgg agacgggcaa cctcacggag ctctactatg ccagggtcac cgctgtcagt gcgggaggcc ggtcagccac caagatgact gacaggttca gctctctgca gcacactacc ctcaagccac ctgatgtgac ctgtatctcc aaagtgagat cgattcagat gattgttcat cctaccccca cgcccatccg tgcaggcgat ggccaccggc taaccctgga agacatcttc catgacctgt tctaccactt agagctccag gtcaaccgca cctaccaaat gcaccttgga gggaagcaga gagaatatga gttcttcggc ctgacccctg acacagagtt ccttggcacc atcatgattt gcgttcccac ctgggccaag gagagtgccc cctacatgtg ccgagtgaag acactgccag accggacatg gacctactcc ttctccggag ccttcctgtt ctccatgggc ttcctcgtcg cagtactctg ctacctgagc tacagatatg tcaccaagcc gcctgcacct cccaactccc tgaacgtcca gcgagtcctg actttccagc cgctgcgctt catccaggag cacgtcctga tccctgtctt tgacctcagc ggccccagca gtctggccca gcctgtccag tactcccaga tcagggtgtc tggacccagg gagcctgcag gagctccaca gcggcatagc ctgtccgaga tcacctactt agggcagcca gacatctcca tcctccagcc ctccaacgtg ccacctcccc agatcctctc cccactgtcc tatgccccaa acgctgcccc tgaggtcggg cccccatcct atgcacctca ggtgaccccc gaagctcaat tcccattcta cgccccacag gccatctcta aggtccagcc ttcctcctat gcccctcaag ccactccgga cagctggcct ccctcctatg gggtatgcat ggaaggttct ggcaaagact cccccactgg gacactttct agtcctaaac accttaggcc taaaggtcag cttcagaaag agccaccagc tggaagctgc atgttaggtg gcctttctct gcaggaggtg acctccttgg ctatggagga atcccaagaa gcaaaatcat tgcaccagcc cctggggatt tgcacagaca gaacatctga cccaaatgtg ctacacagtg gggaggaagg gacaccacag tacctaaagg gccagctccc cctcctctcc tcagtccaga tcgagggcca ccccatgtcc ctccctttgc aacctccttc ccgtccatgt tccccctcgg accaaggtcc aagtccctgg ggcctgctgg agtcccttgt gtgtcccaag gatgaagcca agagcccagc ccctgagacc tcagacctgg agcagcccac agaactggat tctcttttca gaggcctggc cctgactgtg cagtgggagt cctga
Molecular Weight
63,077 Da
OMIM
605457
Vector
pENTR223.1 or pUC
Clone Sequence Report
Provided with product shipment
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of IL22RA1 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for IL22RA1. It may not necessarily be applicable to this product.

NCBI GI #
20810509
NCBI GeneID
58985
NCBI Accession #
BC029273
UniProt Secondary Accession #
Q9HB22; A8K839; B2R9Y9
UniProt Related Accession #
Q8N6P7
NCBI Official Full Name
Homo sapiens interleukin 22 receptor, alpha 1, mRNA
NCBI Official Synonym Full Names
interleukin 22 receptor subunit alpha 1
NCBI Official Symbol
IL22RA1
NCBI Official Synonym Symbols
IL22R; CRF2-9; IL22R1
UniProt Protein Name
Interleukin-22 receptor subunit alpha-1
UniProt Synonym Protein Names
Cytokine receptor class-II member 9; Cytokine receptor family 2 member 9; CRF2-9; ZcytoR11
Protein Family
Interleukin-22 receptor
UniProt Gene Name
IL22RA1
UniProt Synonym Gene Names
IL22R; IL-22 receptor subunit alpha-1; IL-22R-alpha-1; IL-22RA1; CRF2-9
UniProt Entry Name
I22R1_HUMAN
NCBI Protein Information
interleukin-22 receptor subunit alpha-1

NCBI Summary for IL22RA1

The protein encoded by this gene belongs to the class II cytokine receptor family, and has been shown to be a receptor for interleukin 22 (IL22). IL22 receptor is a protein complex that consists of this protein and interleukin 10 receptor, beta (IL10BR/CRFB4), a subunit also shared by the receptor complex for interleukin 10 (IL10). This gene and interleukin 28 receptor, alpha (IL28RA) form a cytokine receptor gene cluster in the chromosomal region 1p36. [provided by RefSeq, Jul 2008]
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UniProt Comments for IL22RA1

IL22RA1: Component of the receptor for IL20, IL22 and IL24. Component of IL22 receptor formed by IL22RA1 and IL10RB enabling IL22 signaling via JAK/STAT pathways. IL22 also induces activation of MAPK1/MAPK3 and Akt kinases pathways. Component of one of the receptor for IL20 and IL24 formed by IL22RA1 and IL20RB also signaling through STATs activation. Mediates IL24 antiangiogenic activity as well as IL24 inhibitory effect on endothelial cell tube formation and differentiation. Belongs to the type II cytokine receptor family.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: 1p36.11

Cellular Component: integral to membrane; plasma membrane

Molecular Function: interferon receptor activity; interleukin-20 binding; protein binding
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Research Articles on IL22RA1

1. FBXW12 functions as an E3 ligase constituent to ubiquitinate and degrade IL-22R and that therapeutic FBXW12 inhibition may enhance IL-22 signaling and bolster mucosal host defense and infection containment.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with IL22RA1 cdna clone

 Products by Pathway  Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Cytokine-cytokine Receptor Interaction Pathway antibodies  Cytokine-cytokine Receptor Interaction Pathway Diagram
 Jak-STAT Signaling Pathway antibodies  Jak-STAT Signaling Pathway Diagram
 Jak-STAT Signaling Pathway antibodies  Jak-STAT Signaling Pathway Diagram

Diseases associated with IL22RA1 cdna clone

 Disease Name  Pubmed Publications
 Breast Neoplasms Antibodies  >1 publications with IL22RA1 and Breast Neoplasms
 Atherosclerosis Antibodies  >1 publications with IL22RA1 and Atherosclerosis
 Neoplasms Antibodies  >1 publications with IL22RA1 and Neoplasms
 Inflammation Antibodies  >1 publications with IL22RA1 and Inflammation

Organs/Tissues associated with IL22RA1 cdna clone

 Organ/Tissue Name  Pubmed Publications
 Thyroid Antibodies  >1 publications with IL22RA1 and Thyroid
 Skin Antibodies  >1 publications with IL22RA1 and Skin
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