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NELF cDNA Clone – Nasal Embryonic LHRH Factor (Human)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1276301

MBS1276301 is a cDNA clone targeting NELF. More details

$595 / 0.01 mg Plasmid + 0.2 mL Glycerol-Stock +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
NELF, cDNA Clone
Full Product Name
NELF cDNA Clone
Product Gene Name
NELF cdna clone
Sequence
ATGGGCGCCG CCGCCTCCAG GAGGAGGGCG CTGAGGAGCG AGGCCATGTC CTCGGTGGCG GCCAAAGTGC GAGCAGCCCG AGCGTTTGGA GAGTACCTGT CCCAGAGTCA CCCTGAGAAC CGCAACGGCG CAGATCACCT GCTGGCTGAT GCCTACTCTG GCCACGACGG GTCCCCCGAG ATGCAGCCGG CCCCCCAGAA CAAGCGCCGC CTGTCCCTCG TCTCCAACGG CTGCTACGAG GGCAGCCTCT CAGAGGAGCC CAGCATTAGG AAGCCCGCAG GCGAGGGCCC TCAGCCTCGA GTGTACACCA TCTCTGGGGA GCCTGCCCTG CTGCCCAGCC CTGAGGCGGA GGCCATTGAG CTGGCGGTGG TGAAGGGGCG GCGGCAGCGG CACCCTCACC ATCACAGCCA GCCCCTGCGC GCCAGCCCTG GTGGCAGCCG GGAGGACGTC AGCAGGCCCT GCCAGAGCTG GGCGGGCAGC CGCCAGGGCT CCAAGGAGTG CCCCGGATGT GCCCAGCTGG CTCCTGGCCC CACCCCTCGG GCCTTTGGGC TGGACCAGCC ACCTCTGCCT GAGACCTCCG GTCGCCGCAA GAAGCTGGAG AGGATGTACA GCGTTGACCG TGTGTCTGAC GACATCCCTA TTCGTACCTG GTTCCCCAAG GAAAATCTTT TCAGCTTCCA GACAGCAACC ACAACTATGC AAGCGAACTT CCGCAAACAC CTGCGCATGG TCGGCAGCCG GAGGGTGAAG GCCCAGACGT TCGCTGAGCG GCGCGAGCGG AGCTTCAGCC GGTCCTGGAG CGACCCCACC CCCATGAAAG CCGACACTTC CCACGACTCC CGAGACAGCA GTGACCTGCA GAGCTCCCAC TGCACGCTGG ACGAGGCCTT CGAGGACCTG GACTGGGACA CTGAGAAGGG CCTGGAGGCT GTGGCCTGCG ACACCGAAGG CTTCGTGCCA CCAAAGGTCA TGCTCATTTC CTCCAAGGTG CCCAAGGCTG AGTACATCCC CACTATCATC CGCCGGGATG ACCCCTCCAT CATCCCCATC CTCTACGACC ATGAGCACGC AACCTTCGAG GACATCCTTG AGGAGATAGA GAGGAAGCTG AACGTCTACC ACAAGGGAGC CAAGATCTGG AAAATGCTGA TTTTCTGCCA GGGAGGTCCT GGACACCTCT ATCTCCTCAA GAACAAGGTG GCCACCTTTG CCAAAGTGGA GAAGGAAGAG GACATGATTC ACTTCTGGAA GCGGCTGAGC CGCCTGATGA GCAAAGTGAA CCCAGAGCCG AACGTCATCC ACATCATGGG CTGCTACATT CTGGGGAACC CCAATGGAGA GAAGCTGTTC CAGAACCTCA GGACCCTCAT GACTCCTTAT AGGGTCACCT TCGAGTCACC CCTGGAGCTC TCAGCCCAAG GGAAGCAGAT GATCGAGACG TACTTTGACT TCCGGTTGTA TCGCCTGTGG AAGAGCCGCC AGCACTCGAA GCTGCTGGAC TTTGACGACG TCCTGTGA
Molecular Weight
57,139 Da
OMIM
608137
Vector
Please Inquire
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of NELF cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for NELF. It may not necessarily be applicable to this product.

NCBI GI #
115527621
NCBI GeneID
26012
NCBI Accession #
BC110498
UniProt Secondary Accession #
Q2TB96; Q6X4V7; Q6X4V8; Q6X4V9; Q8N2M2; Q96SY1; Q9NPM4; Q9NPP3; Q9NPS3
UniProt Related Accession #
Q6X4W1
NCBI Official Full Name
Homo sapiens nasal embryonic LHRH factor, mRNA
NCBI Official Synonym Full Names
NMDA receptor synaptonuclear signaling and neuronal migration factor
NCBI Official Symbol
NSMF
NCBI Official Synonym Symbols
HH9; NELF
UniProt Protein Name
NMDA receptor synaptonuclear signaling and neuronal migration factor
UniProt Synonym Protein Names
Nasal embryonic luteinizing hormone-releasing hormone factor; Nasal embryonic LHRH factor
Protein Family
Negative elongation factor
UniProt Gene Name
NSMF
UniProt Synonym Gene Names
NELF; Nasal embryonic LHRH factor
UniProt Entry Name
NSMF_HUMAN
NCBI Protein Information
NMDA receptor synaptonuclear signaling and neuronal migration factor

NCBI Summary for NELF

The protein encoded by this gene is involved in guidance of olfactory axon projections and migration of luteinizing hormone-releasing hormone neurons. Defects in this gene are a cause of idiopathic hypogonadotropic hypogonadism (IHH). Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2010]
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UniProt Comments for NELF

NSMF: Couples NMDA receptor signaling to the nucleus. Influences outgrowth of olfactory axons and migration of LHRH neurons. Defects in NELF may be associated with idiopathic hypogonadotropic hypogonadism (IHH). IHH is defined as a deficiency of the pituitary secretion of follicle-stimulating hormone and luteinizing hormone, which results in the impairment of pubertal maturation and of reproductive function. 6 isoforms of the human protein are produced by alternative splicing.

Protein type: Adaptor/scaffold

Chromosomal Location of Human Ortholog: 9q34.3

Cellular Component: cortical cytoskeleton; cytoplasm; dendrite; membrane; neuron projection; nuclear envelope; nuclear matrix; nuclear membrane; nucleoplasm; nucleus; perikaryon; postsynaptic density; synapse

Molecular Function: calcium-dependent protein binding

Biological Process: positive regulation of protein amino acid dephosphorylation; regulation of dendrite morphogenesis; regulation of neuron apoptosis; regulation of neuronal synaptic plasticity

Disease: Hypogonadotropic Hypogonadism 9 With Or Without Anosmia
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Research Articles on NELF

1. The nuclear and non-nuclear NELF variant transcripts and proteins were identified, explaining variable NELF cellular localization.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Diseases associated with NELF cdna clone

 Disease Name  Pubmed Publications
 Myocardial Infarction Antibodies  >1 publications with NELF and Myocardial Infarction
 Kidney Diseases Antibodies  >1 publications with NELF and Kidney Diseases

Organs/Tissues associated with NELF cdna clone

 Organ/Tissue Name  Pubmed Publications
 Eye Antibodies  >2 publications with NELF and Eye
 Heart Antibodies  >2 publications with NELF and Heart
 Embryonic Tissue Antibodies  >1 publications with NELF and Embryonic Tissue
 Liver Antibodies  >1 publications with NELF and Liver
 Kidney Antibodies  >1 publications with NELF and Kidney
 Blood Antibodies  >1 publications with NELF and Blood
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