Human PHC3 cDNA Clone Expression Plasmid – Cat# MBS1275886

PHC3 cDNA Clone – Polyhomeotic Homolog 3 (Drosophila) (Human)

Name: PHC3 cDNA Clone; Human; MyBioSource
Brand: MyBioSource
SKU: MBS1275886
Price: 1085 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1275886

MBS1275886 is a cDNA clone targeting PHC3. More details

$1085 / 0.01 mg Plasmid + 0.2 mL Glycerol-Stock +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

PHC3, cDNA Clone

Full Product Name

PHC3 cDNA Clone

Product Gene Name

PHC3 cdna clone

Sequence

ATGGATACTG AACCAAACCC GGGAACATCT TCTGTGTCAA CAACAACCAG CAGTACCACC ACCACCACCA TCACCACTTC CTCCTCTCGA ATGCAGCAGC CACAGATCTC TGTCTACAGT GGTTCAGACC GACATGCTGT ACAGGTAATT CAACAGGCAT TGCATCGGCC CCCCAGCTCA GCTGCTCAGT ACCTTCAGCA AATGTATGCA GCCCAACAAC AGCACTTGAT GCTGCATACT GCAGCTCTTC AGCAGCAGCA TTTAAGCAGC TCCCAGCTTC AGAGCCTTGC TGCTGTTCAG GCAAGTTTGT CCAGTGGAAG ACCATCTACA TCTCCCACAG GAAGTGTCAC ACAGCAGTCA AGTATGTCCC AAACGTCTAT CAACCTCTCC ACTTCTCCTA CACCTGCACA GTTAATAAGC CGTTCCCAGG CTTCCAGTTC TACCAGCGGC AGTATTACCC AACAGACTAT GTTACTAGGG AGTACTTCCC CTACCCTAAC GGCAAGCCAA GCTCAAATGT ATCTCCGAGC TCAAATGCTG ATTTTCACAC CCGCTACCAC TGTGGCTGCT GTACAGTCTG ACATTCCTGT TGTCTCGTCG TCATCGTCAT CTTCCTGTCA GTCTGCAGCT ACTCAGGTTC AGAATTTAAC ATTACGCAGC CAGAAGTTGG GTGTATTATC TAGCTCACAG AATGGTCCAC CAAAAAGCAC TAGTCAAACT CAGTCATTGA CAATTTGTCA TAACAAAACA ACAGTGACCA GTTCTAAAAT CAGCCAACGA GATCCTTCTC CAGAAAGTAA TAAGAAAGGA GAGAGCCCAA GCCTGGAATC ACGAAGCACA GCTGTCACCC GGACATCAAG TATTCACCAG TTAATAGCAC CAGCTTCATA TTCTCCAATT CAGCCTCATT CTCTAATAAA ACATCAGCAG ATTCCTCTTC ATTCACCACC TTCCAAAGTT TCCCATCATC AGCTGATATT ACAACAGCAG CAACAGCAAA TTCAGCCAAT CACACTTCAG AATTCAACTC AAGACCCACC CCCATCCCAG CACTGTATAC CACTCCAGAA CCATGGCCTT CCTCCAGCTC CCAGTAATGC CCAGTCACAG CATTGTTCAC CGATTCAGAG TCATCCCTCT CCTTTAACAG TGTCTCCTAA TCAGTCACAG TCAGCACAGC AGTCTGTAGT GGTGTCTCCT CCACCACCTC ATTCACCAAG TCAGTCTCCT ACTATAATTA TTCATCCACA AGCACTTATT CAGCCACACC CTCTTGTGTC ATCAGCTCTC CAGCCAGGGC CAAATTTGCA GCAGTCCACT GCTAATCAGG TGCAAGCTAC AGCACAGTTG AATCTTCCAT CCCATCTTCC ACTTCCAGCT TCCCCTGTTG TACACATTGG CCCAGTTCAG CAGTCTGCCT TGGTATCCCC AGGCCAGCAG ATTGTCTCTC CATCACACCA GCAATATTCA TCCCTGCAGT CCTCTCCAAT CCCAATTGCA AGTCCTCCAC AGATGTCGAC ATCTCCTCCA GCTCAGATTC CACCACTGCC CTTGCAGTCT ATGCAGTCTT TACAAGTGCA GCCTGAAATT CTGTCCCAGG GCCAGGTTTT GGTGCAGAAT GCTTTGGTGT CAGAAGAGGA ACTTCCAGCT GCAGAAGCTT TGGTCCAGTT GCCATTTCAG ACTCTTCCTC CTCCACAGAC TGTTGCGGTA AACCTACAAG TGCAACCACC AGCACCTGTT GATCCACCAG TGGTTTATCA GGTAGAAGAT GTGTGTGAAG AAGAAATGCC AGAAGAGTCA GATGAATGTG TCCGGATGGA TAGAACCCCA CCACCACCCA CTTTGTCTCC AGCAGCTATA ACAGTGGGGA GAGGAGAAGA TTTGACTTCT GAACATCCTT TGTTAGAGCA AGTGGAATTA CCTGCTGTGG CATCAGTCAG TGCTTCAGTA ATTAAATCTC CATCAGATCC CTCACATGTT TCTGTTCCAC CACCTCCATT GTTACTTCCA GCTGCCACCA CAAGGAGTAA CAGTACATCT ATGCACAGTA GCATTCCCAG TATAGAGAAC AAACCTCCAC AGGCTATTGT TAAACCACAG ATCCTAACCC ATGTTATTGA AGGCTTTGTG ATTCAGGAGG GATTGGAGCC ATTTCCTGTG AGTCGTTCCT CTTTGCTAAT AGAACAGCCT GTGAAAAAAC GGCCTCTTTT GGATAATCAG GTGATAAATT CAGTGTGTGT TCAGCCAGAG CTACAGAATA ATACAAAACA TGCGGATAAT TCATCTGACA CAGAGATGGA AGACATGATT GCTGAAGAGA CATTAGAAGA AATGGACAGT GAGTTGCTCA AGTGTGAATT CTGTGGGAAA ATGGGATATG CTAATGAATT TTTGCGGTCA AAACGATTCT GCACTATGTC ATGTGCCAAA AGGTACAATG TTAGCTGTTC TAAAAAATTT GCACTTAGTC GTTGGAATCG TAAGCCTGAT AATCAAAGTC TTGGGCATCG TGGCCGTCGT CCAAGTGGCC CTGATGGGGC AGCGAGAGAA CATATCCTTA GGCAGCTTCC AATTACTTAT CCATCTGCAG AAGAAGACTT GGCTTCTCAT GAAGATTCTG TGCCATCTGC TATGACAACT CGTCTGCGCA GGCAGAGCGA GCGGGAAAGA GAACGTGAGC TTCGGGATGT GAGAATTCGG AAAATGCCTG AGAACAGTGA CTTGCTACCA GTTGCACAAA CAGAGCCATC TATATGGACA GTTGATGATG TCTGGGCCTT CATCCATTCT TTGCCTGGCT GCCAGGATAT CGCAGATGAA TTCAGAGCAC AGGAGATTGA TGGACAGGCC CTTCTCTTGC TGAAAGAAGA CCATCTCATG AGTGCAATGA ATATCAAGCT AGGCCCAGCC CTGAAGATCT GTGCACGCAT CAACTCTCTG AAGGAATCTT AA

Molecular Weight

107,480 Da

Vector

Please Inquire

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of PHC3 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for PHC3. It may not necessarily be applicable to this product.

NCBI GI #

124298013

NCBI GeneID

80012

NCBI Accession #

BC131772

UniProt Secondary Accession #

Q5HYF0; Q6NSG2; Q8NFT7; Q8NFZ1; Q8TBM2; Q9H971; Q9H9I4; A2RRP9

UniProt Related Accession #

Q8NDX5

NCBI Official Full Name

Homo sapiens polyhomeotic homolog 3 (Drosophila), mRNA

NCBI Official Synonym Full Names

polyhomeotic homolog 3

NCBI Official Symbol

PHC3

NCBI Official Synonym Symbols

EDR3; HPH3

UniProt Protein Name

Polyhomeotic-like protein 3

UniProt Synonym Protein Names

Early development regulatory protein 3; Homolog of polyhomeotic 3; hPH3

Protein Family

Polyhomeotic-like protein

UniProt Gene Name

PHC3

UniProt Synonym Gene Names

EDR3; PH3; hPH3

UniProt Entry Name

PHC3_HUMAN

NCBI Protein Information

polyhomeotic-like protein 3

UniProt Comments for PHC3

PHC3: Component of a Polycomb group (PcG) multiprotein PRC1- like complex, a complex class required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility. 7 isoforms of the human protein are produced by alternative splicing.

Protein type: Transcription regulation

Chromosomal Location of Human Ortholog: 3q26.2

Cellular Component: actin cytoskeleton; intracellular membrane-bound organelle; nucleoplasm; nucleus; PcG protein complex

Molecular Function: protein binding

Biological Process: protein sumoylation

Research Articles on PHC3

1. Data show that polycomb-group proteins BMI1, PHC3, CBX6 and CBX7 expression was significantly increased during imatinib treatment.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Diseases associated with PHC3 cdna clone

Disease Name	Pubmed Publications
Neoplasms Antibodies	>5 publications with PHC3 and Neoplasms
Neoplasms, Experimental Antibodies	>2 publications with PHC3 and Neoplasms, Experimental
Acute Kidney Injury Antibodies	>1 publications with PHC3 and Acute Kidney Injury
Necrosis Antibodies	>1 publications with PHC3 and Necrosis
Kidney Neoplasms Antibodies	>1 publications with PHC3 and Kidney Neoplasms
Anemia Antibodies	>1 publications with PHC3 and Anemia
Anemia, Hemolytic Antibodies	>1 publications with PHC3 and Anemia, Hemolytic
Kidney Diseases Antibodies	>1 publications with PHC3 and Kidney Diseases