Human PTH2R cDNA Clone Expression Plasmid – Cat# MBS1274480

PTH2R cDNA Clone – Parathyroid Hormone 2 Receptor (Human)

Name: PTH2R cDNA Clone; Parathyroid Hormone 2 Receptor; Human; MyBioSource
Brand: MyBioSource
SKU: MBS1274480
Price: 645 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1274480

MBS1274480 is a cDNA clone targeting PTH2R. More details

$645 / 0.01 mg Plasmid + 0.2 mL Glycerol-Stock +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

PTH2R, cDNA Clone

Full Product Name

PTH2R cDNA Clone

Product Gene Name

PTH2R cdna clone

Sequence

atggccgggc tgggggcgtc gctccacgtc tggggttggc taatgctcgg cagctgcctc ctggccagag cccagctgga ttctgatggc accattacta tagaggagca gattgtcctt gtgctgaaag cgaaagtaca atgtgaactc aacatcacag ctcaactcca ggagggagaa ggtaattgtt tccctgaatg ggatggactc atttgttggc ccagaggaac agtggggaaa atatcggctg ttccatgccc tccttatatt tatgacttca accataaagg agttgctttc cgacactgta accccaatgg aacatgggat tttatgcaca gcttaaataa aacatgggcc aattattcag actgccttcg ctttctgcag ccagatatca gcataggaaa gcaagaattc tttgaacgcc tctatgtaat gtataccgtt ggctactcca tctcttttgg ttccttggct gtggctattc tcatcattgg ttacttcaga cgattgcatt gcactaggaa ctatatccac atgcacttat ttgtgtcttt catgctgaga gctacaagca tctttgtcaa agacagagta gtccatgctc acataggagt aaaggagctg gagtccctaa taatgcagga tgacccacaa aattccattg aggcaacttc tgtggacaaa tcacaatata tcgggtgcaa gattgctgtt gtgatgttta tttacttcct ggctacaaat tattattgga tcctggtgga aggtctctac ctgcataatc tcatctttgt ggctttcttt tcggacacca aatacctgtg gggcttcatc ttgataggct gggggtttcc agcagcattt gttgcagcat gggctgtggc acgagcaact ctggctgatg cgaggtgctg ggaacttagt gctggagaca tcaagtggat ttatcaagca ccgatcttag cagctattgg gctgaatttt attctgtttc tgaatacggt tagagttcta gctaccaaaa tctgggagac caatgcagtt gggcatgaca caaggaagca atacaggaaa ctggccaaat cgacactggt cctggtccta gtctttggag tgcattacat cgtgttcgta tgcctgcctc actccttcac tgggctcggg tgggagatcc gcatgcactg tgagctcttc ttcaactcct ttcagggttt ctttgtgtct atcatctact gctactgcaa tggagaggtt caggcagagg tgaagaagat gtggagtcgg tggaacctct ccgtggactg gaaaaggaca ccgccatgtg gcagccgcag atgcggctca gtgctcacca ccgtgacgca cagcaccagc agccagtcac aggtggcggc cagcacacgc atggtgctta tctctggcaa agctgccaag atcgccagca gacagcctga cagccacatc actttacctg gctatgtctg gagtaactca gagcaggact gcctgccaca ctctttccac gaggagacca aggaagatag tgggaggcag ggagatgata ttctaatgga gaagccttcc aggcctatgg aatctaaccc agacactgaa ggatgccaag gagaaactga ggatgttctc tga

Molecular Weight

62,236 Da

OMIM

601469

Vector

Please Inquire

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of PTH2R cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for PTH2R. It may not necessarily be applicable to this product.

NCBI GI #

22477310

NCBI GeneID

5746

NCBI Accession #

BC036811

UniProt Secondary Accession #

Q8N429

UniProt Related Accession #

P49190

NCBI Official Full Name

Homo sapiens parathyroid hormone 2 receptor, mRNA

NCBI Official Synonym Full Names

parathyroid hormone 2 receptor

NCBI Official Symbol

PTH2R

NCBI Official Synonym Symbols

PTHR2

UniProt Protein Name

Parathyroid hormone 2 receptor

Protein Family

Parathyroid hormone 2 receptor

UniProt Gene Name

PTH2R

UniProt Synonym Gene Names

PTHR2; PTH2 receptor

UniProt Entry Name

PTH2R_HUMAN

NCBI Protein Information

parathyroid hormone 2 receptor

NCBI Summary for PTH2R

The protein encoded by this gene is a member of the G-protein coupled receptor 2 family. This protein is a receptor for parathyroid hormone (PTH). This receptor is more selective in ligand recognition and has a more specific tissue distribution compared to parathyroid hormone receptor 1 (PTHR1). It is activated only by PTH and not by parathyroid hormone-like hormone (PTHLH) and is particularly abundant in brain and pancreas. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2013]

UniProt Comments for PTH2R

PTH2R: This is a specific receptor for parathyroid hormone. The activity of this receptor is mediated by G proteins which activate adenylyl cyclase. PTH2R may be responsible for PTH effects in a number of physiological systems. It may play a significant role in pancreatic function. PTH2R presence in neurons indicates that it may function as a neurotransmitter receptor. Belongs to the G-protein coupled receptor 2 family.

Protein type: Membrane protein, integral; Membrane protein, multi-pass; Receptor, GPCR; GPCR, family 2

Chromosomal Location of Human Ortholog: 2q33

Cellular Component: integral to plasma membrane; plasma membrane

Molecular Function: parathyroid hormone receptor activity; protein binding

Research Articles on PTH2R

1. Variation in the PTH2R gene (Chr2q34, rs897083) may contribute to the age-associated degenerative manifestations that develop at the lumbar spine

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with PTH2R cdna clone

Products by Pathway	Pathway Diagram
Class B/2 (Secretin Family Receptors) Pathway antibodies	Class B/2 (Secretin Family Receptors) Pathway Diagram
G Alpha (s) Signalling Events Pathway antibodies	G Alpha (s) Signalling Events Pathway Diagram
GPCR Downstream Signaling Pathway antibodies	GPCR Downstream Signaling Pathway Diagram
GPCR Ligand Binding Pathway antibodies	GPCR Ligand Binding Pathway Diagram
GPCRs, Class B Secretin-like Pathway antibodies	GPCRs, Class B Secretin-like Pathway Diagram
Neuroactive Ligand-receptor Interaction Pathway antibodies	Neuroactive Ligand-receptor Interaction Pathway Diagram
Neuroactive Ligand-receptor Interaction Pathway antibodies	Neuroactive Ligand-receptor Interaction Pathway Diagram
Signal Transduction Pathway antibodies	Signal Transduction Pathway Diagram
Signaling By GPCR Pathway antibodies	Signaling By GPCR Pathway Diagram

Diseases associated with PTH2R cdna clone

Disease Name	Pubmed Publications
Nervous System Diseases Antibodies	>2 publications with PTH2R and Nervous System Diseases
Leukemia Antibodies	>1 publications with PTH2R and Leukemia

Organs/Tissues associated with PTH2R cdna clone

Organ/Tissue Name	Pubmed Publications
Brain Antibodies	>12 publications with PTH2R and Brain
Lung Antibodies	>1 publications with PTH2R and Lung
Testis Antibodies	>1 publications with PTH2R and Testis
Bone Marrow Antibodies	>1 publications with PTH2R and Bone Marrow
Skin Antibodies	>1 publications with PTH2R and Skin