Human REC8 cDNA Clone Expression Plasmid – Cat# MBS1273277

REC8 cDNA Clone – REC8 Homolog (Yeast) (Human)

Name: REC8 cDNA Clone; REC8 Homolog (Yeast); Human; MyBioSource
Brand: MyBioSource
SKU: MBS1273277
Price: 400 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1273277

MBS1273277 is a cDNA clone targeting REC8. More details

$400 / 0.01 mg Plasmid + 0.2 mL Glycerol-Stock +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

REC8, cDNA Clone

Full Product Name

REC8 cDNA Clone

Product Gene Name

REC8 cdna clone

Sequence

atgttctact atcccaacgt gcttcagcgc cacaccggct gctttgccac catctggctg gcggcgactc gcggcagccg gttggtgaag cgcgaatacc tgagggtgaa tgtggtgaaa acctgcgagg aaatcctcaa ttacgtgctg gtacgagtgc aacccccgca gcccggcctg ccgcggcccc gcttctccct ctatctctca gcccaacttc agatcggtgt gatccgcgtc tattctcaac aatgccagta cctcgtggag gacatccagc acatcttgga gcgcctccac cgtgcccagc tgcagatccg aatagatatg gagactgagc tacccagcct gctgcttcct aaccacctgg ccatgatgga gaccctagaa gatgctccag atcccttttt tgggatgatg tctgtggatc ccagacttcc tagtcctttc gatatccctc agattcgaca cctcttagag gctgcaatcc cagagagagt tgaagagatc cctcctgaag ttcctacaga gcccagggag ccagagagga ttccggtcac tgtgctgcca cctgaggcca tcacgatcct ggaggcagag cccatacgga tgctggagat tgagggtgaa cgggagctcc cagaggtcag ccgccgagaa ctggacctgc tgatcgcaga ggaagaagaa gctatcttgt tagaaatccc gcggctccca cctccagctc ctgcagaggt ggaaggaata ggagaggcac tgggtcctga ggagctgagg ctgacaggct gggaacctgg ggccctactc atggaggtga cccccccgga ggagctgcgt ctgccagccc cacccagccc agagaggagg cccccagtcc ccccacctcc tcgccgccgc cgtcgtcgcc ggttactgtt ctgggacaag gagactcaga tctccccgga gaaattccag gaacaactgc aaaccagagc ccactgctgg gaatgtccta tggtgcagcc gcccgagagg accatcagag gccctgcgga gttgttcaga accccaactc tctctggctg gctaccccct gaactactgg gtctctggac ccattgtgcc cagccacccc caaaagccct caggcgagag ctgcctgagg aggcagccgc tgaggaggaa aggagaaaga ttgaagttcc aagtgagatt gaggtcccga gggaggccct ggagcccagt gttcccctta tggtgtcttt agagatctcc ctagaggcag ctgaagagga gaagtcccgc atcagcctca tcccaccaga agaacggtgg gcctggcctg aggtggaggc gccagaagct cctgcattgc ccgtggtgcc tgaactccct gaggtgccca tggagatgcc tttggtgctg cccccagagc tcgagctgct ctcactggaa gcagtgcaca gggcagtggc actggagctg caggctaaca gggagcccga cttcagcagc ctggtgtcac ctctcagccc ccgcaggatg gctgcccggg tcttctacct gctcctggtg ctctcagcgc aacagattct tcacgtgaaa caagaaaagc catatggtcg cctcctgatc cagccggggc ccagattcca ctga

Molecular Weight

60,774 Da

OMIM

608193

Vector

pENTR223.1 or pUC

Clone Sequence Report

Provided with product shipment

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of REC8 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for REC8. It may not necessarily be applicable to this product.

NCBI GI #

14790109

NCBI GeneID

9985

NCBI Accession #

BC010887

UniProt Secondary Accession #

Q658V5; Q6IA92; Q8WUV8; Q9BTF2; Q9NVQ9; A8K576; D3DS62

UniProt Related Accession #

O95072

NCBI Official Full Name

Homo sapiens REC8 homolog (yeast), mRNA

NCBI Official Synonym Full Names

REC8 meiotic recombination protein

NCBI Official Symbol

REC8

NCBI Official Synonym Symbols

Rec8p; REC8L1; HR21spB

UniProt Protein Name

Meiotic recombination protein REC8 homolog

UniProt Synonym Protein Names

Cohesin Rec8p

Protein Family

Meiotic recombination protein

UniProt Gene Name

REC8

UniProt Synonym Gene Names

REC8L1

UniProt Entry Name

REC8_HUMAN

NCBI Protein Information

meiotic recombination protein REC8 homolog

NCBI Summary for REC8

This gene encodes a member of the kleisin family of SMC (structural maintenance of chromosome) protein partners. The protein localizes to the axial elements of chromosomes during meiosis in both oocytes and spermatocytes. In the mouse, the homologous protein is a key component of the meiotic cohesion complex, which regulates sister chromatid cohesion and recombination between homologous chromosomes. Multiple alternatively spliced variants, encoding the same protein, have been found for this gene. [provided by RefSeq, Jul 2008]

UniProt Comments for REC8

REC8: Required during meiosis for separation of sister chromatids and homologous chromosomes. Proteolytic cleavage of REC8 on chromosome arms by separin during anaphase I allows for homologous chromosome separation in meiosis I and cleavage of REC8 on centromeres during anaphase II allows for sister chromatid separation in meiosis II. Belongs to the rad21 family. 2 isoforms of the human protein are produced by alternative splicing.

Chromosomal Location of Human Ortholog: 14q11.2-q12

Cellular Component: nucleus

Biological Process: meiosis; meiotic recombination; sister chromatid cohesion; spermatogenesis

Research Articles on REC8

1. Data show that REC8 is constitutively expressed in tumour cells, along with SGOL1 and SGOL2, and that REC8 becomes modified after irradiation.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with REC8 cdna clone

Products by Pathway	Pathway Diagram
Cell Cycle Pathway antibodies	Cell Cycle Pathway Diagram
Chromosome Maintenance Pathway antibodies	Chromosome Maintenance Pathway Diagram
Meiosis Pathway antibodies	Meiosis Pathway Diagram
Meiotic Synapsis Pathway antibodies	Meiotic Synapsis Pathway Diagram
Oocyte Meiosis Pathway antibodies	Oocyte Meiosis Pathway Diagram
Oocyte Meiosis Pathway antibodies	Oocyte Meiosis Pathway Diagram

Diseases associated with REC8 cdna clone

Disease Name	Pubmed Publications
Infertility, Male Antibodies	>9 publications with REC8 and Infertility, Male
Infertility, Female Antibodies	>6 publications with REC8 and Infertility, Female
Neoplasms Antibodies	>5 publications with REC8 and Neoplasms
Drug Toxicity Antibodies	>1 publications with REC8 and Drug Toxicity
Congenital Abnormalities Antibodies	>1 publications with REC8 and Congenital Abnormalities
Oligospermia Antibodies	>1 publications with REC8 and Oligospermia
Lung Neoplasms Antibodies	>1 publications with REC8 and Lung Neoplasms
Heart Defects, Congenital Antibodies	>1 publications with REC8 and Heart Defects, Congenital
Kidney Diseases Antibodies	>1 publications with REC8 and Kidney Diseases
Neoplasms, Experimental Antibodies	>1 publications with REC8 and Neoplasms, Experimental

Organs/Tissues associated with REC8 cdna clone

Organ/Tissue Name	Pubmed Publications
Testis Antibodies	>14 publications with REC8 and Testis
Ovary Antibodies	>11 publications with REC8 and Ovary
Embryonic Tissue Antibodies	>2 publications with REC8 and Embryonic Tissue
Kidney Antibodies	>2 publications with REC8 and Kidney
Heart Antibodies	>1 publications with REC8 and Heart
Stomach Antibodies	>1 publications with REC8 and Stomach
Lung Antibodies	>1 publications with REC8 and Lung
Thymus Antibodies	>1 publications with REC8 and Thymus