Human SLC19A2 cDNA Clone Expression Plasmid – Cat# MBS1273906

SLC19A2 cDNA Clone – Solute Carrier Family 19 (Thiamine Transporter), Member 2 (Human)

Name: SLC19A2 cDNA Clone; Human; MyBioSource
Brand: MyBioSource
SKU: MBS1273906
Price: 370 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1273906

MBS1273906 is a cDNA clone targeting SLC19A2. More details

$370 / 0.01 mg Plasmid + 0.2 mL Glycerol-Stock +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

SLC19A2, cDNA Clone

Full Product Name

SLC19A2 cDNA Clone

Product Gene Name

SLC19A2 cdna clone

Sequence

atggatgtgc ccggcccggt gtctcggcgg gcggcggcgg cggcggccac tgtgctcctg cggaccgctc gggtccgtcg cgaatgctgg ttcttgccga ccgcgctgct ctgcgcctac ggcttcttcg ccagcctcag gccgtccgag cccttcctga ccccgtacct gctggggccg gacaagaacc tgaccgagag ggaggaaccc aagccagacc gtctccttgt attgaaagta ctatggaatg atttcctgat gtgctactcc tctcgccctc ttctctgctg gtctgtgtgg tgggccctct ctacctgtgg ctattttcaa gttgtgaact acacacaggg cctgtgggag aaagtgatgc cttctcgcta tgctgctatc tataatggtg gcgtggaggc cgtttcaacc ttactgggtg ctgttgctgt gtttgcagtt ggttatataa aaatatcctg gtcaacttgg ggagaaatga cattatctct cttttctctc ctgattgctg ctgcagtgta tatcatggac actgtgggta acatttgggt gtgctatgca tcctatgttg tcttcagaat catctacatg ttactcatca cgatagcaac ttttcaaatt gctgcaaacc tcagcatgga acgctatgcc ctagtatttg gtgtaaatac cttcattgcc ctggcactgc agacgctgct cactctaatt gtggtagatg ccagtggcct tggattagaa attaccactc agtttttgat ctatgccagt tattttgcac tcatcgctgt ggttttcctg gccagtggtg cagtcagtgt tatgaagaaa tgtagaaagc tggaagatcc acaatcaagt tctcaagtaa ccacttcata a

Molecular Weight

32,858 Da

OMIM

249270

Vector

Please Inquire

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of SLC19A2 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for SLC19A2. It may not necessarily be applicable to this product.

NCBI GI #

17391214

NCBI GeneID

10560

NCBI Accession #

BC018514

UniProt Secondary Accession #

Q8WV87; Q9UBL7; Q9UKJ2; Q9UN31; Q9UN43; B2R9H0; B4E1X4

UniProt Related Accession #

O60779

NCBI Official Full Name

Homo sapiens solute carrier family 19 (thiamine transporter), member 2, mRNA

NCBI Official Synonym Full Names

solute carrier family 19 member 2

NCBI Official Symbol

SLC19A2

NCBI Official Synonym Symbols

TC1; THT1; TRMA; THMD1; THTR1

UniProt Protein Name

Thiamine transporter 1

UniProt Synonym Protein Names

Solute carrier family 19 member 2; Thiamine carrier 1; TC1

Protein Family

Thiamine transporter

UniProt Gene Name

SLC19A2

UniProt Synonym Gene Names

THT1; TRMA; ThTr-1; ThTr1; TC1

UniProt Entry Name

S19A2_HUMAN

NCBI Protein Information

thiamine transporter 1

NCBI Summary for SLC19A2

This gene encodes the thiamin transporter protein. Mutations in this gene cause thiamin-responsive megaloblastic anemia syndrome (TRMA), which is an autosomal recessive disorder characterized by diabetes mellitus, megaloblastic anemia and sensorineural deafness. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2016]

UniProt Comments for SLC19A2

SLC19A2: High-affinity transporter for the intake of thiamine. Defects in SLC19A2 are the cause of thiamine-responsive megaloblastic anemia syndrome (TRMA); also known as Rogers syndrome. TRMA is an autosomal recessive disease with features that include megaloblastic anemia, mild thrombocytopenia and leucopenia, sensorineural deafness and diabetes mellitus. Belongs to the reduced folate carrier (RFC) transporter (TC 2.A.48) family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Transporter; Membrane protein, multi-pass; Transporter, SLC family

Chromosomal Location of Human Ortholog: 1q23.3

Cellular Component: integral to plasma membrane; plasma membrane

Molecular Function: protein binding; thiamin transmembrane transporter activity; thiamin uptake transmembrane transporter activity

Biological Process: thiamin and derivative metabolic process

Disease: Thiamine-responsive Megaloblastic Anemia Syndrome

Research Articles on SLC19A2

1. A novel homozygous SLC19A2 gene mutation c.[205G>T], p.[(Val69Phe)] causing thiamine responsive megaloblastic anemia syndrome.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with SLC19A2 cdna clone

Products by Pathway	Pathway Diagram
Metabolism Pathway antibodies	Metabolism Pathway Diagram
Metabolism Of Vitamins And Cofactors Pathway antibodies	Metabolism Of Vitamins And Cofactors Pathway Diagram
Metabolism Of Water-soluble Vitamins And Cofactors Pathway antibodies	Metabolism Of Water-soluble Vitamins And Cofactors Pathway Diagram
Vitamin B1 (thiamin) Metabolism Pathway antibodies	Vitamin B1 (thiamin) Metabolism Pathway Diagram
Vitamin Digestion And Absorption Pathway antibodies	Vitamin Digestion And Absorption Pathway Diagram
Vitamin Digestion And Absorption Pathway antibodies	Vitamin Digestion And Absorption Pathway Diagram

Diseases associated with SLC19A2 cdna clone

Disease Name	Pubmed Publications
Neoplasms Antibodies	>61 publications with SLC19A2 and Neoplasms
Anemia Antibodies	>53 publications with SLC19A2 and Anemia
Neoplasms, Experimental Antibodies	>23 publications with SLC19A2 and Neoplasms, Experimental
Thiamine responsive megaloblastic anemia syndrome Antibodies	>16 publications with SLC19A2 and Thiamine responsive megaloblastic anemia syndrome
Drug Toxicity Antibodies	>12 publications with SLC19A2 and Drug Toxicity
Neural Tube Defects Antibodies	>10 publications with SLC19A2 and Neural Tube Defects
Breast Neoplasms Antibodies	>8 publications with SLC19A2 and Breast Neoplasms
Brain Diseases Antibodies	>8 publications with SLC19A2 and Brain Diseases
Heart Diseases Antibodies	>5 publications with SLC19A2 and Heart Diseases
Kidney Diseases Antibodies	>4 publications with SLC19A2 and Kidney Diseases

Organs/Tissues associated with SLC19A2 cdna clone

Organ/Tissue Name	Pubmed Publications
Liver Antibodies	>20 publications with SLC19A2 and Liver
Kidney Antibodies	>16 publications with SLC19A2 and Kidney
Brain Antibodies	>10 publications with SLC19A2 and Brain
Eye Antibodies	>9 publications with SLC19A2 and Eye
Placenta Antibodies	>6 publications with SLC19A2 and Placenta
Heart Antibodies	>6 publications with SLC19A2 and Heart
Testis Antibodies	>3 publications with SLC19A2 and Testis
Muscle Antibodies	>3 publications with SLC19A2 and Muscle
Lung Antibodies	>2 publications with SLC19A2 and Lung
Vascular Antibodies	>2 publications with SLC19A2 and Vascular