Human SSH2 cDNA Clone Expression Plasmid – Cat# MBS1265683

SSH2 cDNA Clone – Slingshot Homolog 2 (Drosophila) (Human)

Name: SSH2 cDNA Clone; Slingshot Homolog 2 (Drosophila); Human; MyBioSource
Brand: MyBioSource
SKU: MBS1265683
Price: 235 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1265683

MBS1265683 is a cDNA clone targeting SSH2. More details

$235 / 0.01 mg Plasmid + 0.2 mL Glycerol-Stock +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

SSH2, cDNA Clone

Full Product Name

SSH2 cDNA Clone

Product Gene Name

SSH2 cdna clone

Sequence

atgattcctt acttctccgc caacgcggtc atctcgcaga acgccatcaa ccagctcatc agcgagagct ttctaactgt caaaggtgct gccctttttc taccacgggg aaatggctca tccacaccaa gaatcagcca cagacggaac aagcatgcag gcgatctcca acagcatctc caagcaatgt tcattttact ccgcccagaa gacaacatca ggctggctgt aagactggaa agtacttacc agaatcgaac acgctatatg gtagtggttt caactaatgg tagacaagac actgaagaaa gcatcgtcct aggaatggat ttctcctcta atgacagtag cacttgtacc atgggcttag ttttgcctct ctggagcgac acgctaattc atttggatgg tgatggtggg ttcagtgtat cgacggataa cagagttcac atattcaaac ctgtatctgt gcaggcaatg tgggttgaca gggattcaag gaacaaacac tgtgatgtac tattggtgga agaatga

Molecular Weight

51,492 Da

OMIM

606779

Vector

pENTR223.1 or pUC

Clone Sequence Report

Provided with product shipment

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of SSH2 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for SSH2. It may not necessarily be applicable to this product.

NCBI GI #

33989949

NCBI GeneID

85464

NCBI Accession #

BC011636

UniProt Secondary Accession #

Q8TDB5; Q8WYL1; Q8WYL2; Q96F40; Q96H36; Q9C0D8

UniProt Related Accession #

Q76I76

NCBI Official Full Name

Homo sapiens slingshot homolog 2 (Drosophila), mRNA

NCBI Official Synonym Full Names

slingshot protein phosphatase 2

NCBI Official Symbol

SSH2

NCBI Official Synonym Symbols

SSH-2; SSH-2L

UniProt Protein Name

Protein phosphatase Slingshot homolog 2

UniProt Synonym Protein Names

SSH-like protein 2; SSH-2L; hSSH-2L

Protein Family

Protein phosphatase Slingshot

UniProt Gene Name

SSH2

UniProt Synonym Gene Names

KIAA1725; SSH2L; SSH-2L; hSSH-2L

UniProt Entry Name

SSH2_HUMAN

NCBI Protein Information

protein phosphatase Slingshot homolog 2

NCBI Summary for SSH2

This gene encodes a protein tyrosine phosphatase that plays a key role in the regulation of actin filaments. The encoded protein dephosphorylates and activates cofilin, which promotes actin filament depolymerization. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2013]

UniProt Comments for SSH2

SSH2: Protein phosphatase which regulates actin filament dynamics. Dephosphorylates and activates the actin binding/depolymerizing factor cofilin, which subsequently binds to actin filaments and stimulates their disassembly. Inhibitory phosphorylation of cofilin is mediated by LIMK1, which may also be dephosphorylated and inactivated by this protein. Belongs to the protein-tyrosine phosphatase family. 4 isoforms of the human protein are produced by alternative splicing.

Protein type: Actin-binding; EC 3.1.3.48; EC 3.1.3.16; Protein phosphatase, dual-specificity

Chromosomal Location of Human Ortholog: 17q11.2

Cellular Component: cytoplasm; extracellular space

Molecular Function: actin binding; phosphoprotein phosphatase activity

Biological Process: actin cytoskeleton organization and biogenesis; protein amino acid dephosphorylation; regulation of actin polymerization and/or depolymerization; regulation of axonogenesis

Research Articles on SSH2

1. Novel signaling pathway consisting of chemoattractant GPCR/Galphai protein, PLC, PKCbeta and PKDs that regulates SSH2/cofilin activity, F-actin polymerization and directional assembly of actin cytoskeleton in neutrophil chemotaxis was identified.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with SSH2 cdna clone

Products by Pathway	Pathway Diagram
Regulation Of Actin Cytoskeleton Pathway antibodies	Regulation Of Actin Cytoskeleton Pathway Diagram
Regulation Of Actin Cytoskeleton Pathway antibodies	Regulation Of Actin Cytoskeleton Pathway Diagram
Regulation Of Actin Cytoskeleton Pathway antibodies	Regulation Of Actin Cytoskeleton Pathway Diagram

Diseases associated with SSH2 cdna clone

Disease Name	Pubmed Publications
Neoplasms Antibodies	>2 publications with SSH2 and Neoplasms
Liver Neoplasms Antibodies	>1 publications with SSH2 and Liver Neoplasms
Carcinoma, Hepatocellular Antibodies	>1 publications with SSH2 and Carcinoma, Hepatocellular
Death Antibodies	>1 publications with SSH2 and Death
Liver Diseases Antibodies	>1 publications with SSH2 and Liver Diseases

Organs/Tissues associated with SSH2 cdna clone

Organ/Tissue Name	Pubmed Publications
Ascites Antibodies	>1 publications with SSH2 and Ascites
Muscle Antibodies	>1 publications with SSH2 and Muscle
Stomach Antibodies	>1 publications with SSH2 and Stomach
Lung Antibodies	>1 publications with SSH2 and Lung
Thyroid Antibodies	>1 publications with SSH2 and Thyroid