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TOB1 cDNA Clone – Transducer of ERBB2, 1 (Human)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1277631

MBS1277631 is a cDNA clone targeting TOB1. More details

$235 / 0.01 mg Plasmid + 0.2 mL Glycerol-Stock +1 FREE 8GB USB
Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
TOB1, cDNA Clone
Full Product Name
TOB1 cDNA Clone
Product Gene Name
TOB1 cdna clone
Sequence
atgcagcttg aaatccaagt agcactaaat tttattattt cgtatttgta caataagctt cccaggagac gtgtcaacat ttttggtgaa gaacttgaaa gacttcttaa gaagaaatat gaagggcact ggtatcctga aaagccatac aaaggatcgg ggtttagatg tatacacata ggggagaaag tggacccagt gattgaacaa gcatccaaag agagtggttt ggacattgat gatgttcgtg gcaatctgcc acaggatctt agtgtttgga tcgacccatt tgaggtttct taccaaattg gtgaaaaggg accagtgaag gtgctttacg tggatgataa taatgaaaat ggatgtgagt tggataagga gatcaaaaac agctttaacc cagaggccca ggtttttatg cccataagtg acccagcctc atcagtgtcc agctctccat cgcctccttt tggtcactct gctgctgtaa gccctacctt catgccccgg tccactcagc ctttaacctt taccactgcc acttttgctg ccaccaagtt cggctctacc aaaatgaaga atagtggccg tagcaacaag gttgcacgta cttctcccat caacctcggc ttgaatgtga atgacctctt gaagcagaaa gccatctctt cctcaatgca ctctctgtat gggcttggct tgggtagcca gcagcagcca cagcaacagc agcagccagc ccagccgcca ccgccaccac caccaccaca gcagcaacaa cagcagaaaa cctctgctct ttctcctaat gccaaggaat ttatttttcc taatatgcag ggtcaaggta gtagtaccaa tggaatgttc ccaggtgaca gcccccttaa cctcagtcct ctccagtaca gtaatgcctt tgatgtgttt gcagcctatg gaggcctcaa tgagaagtct tttgtagatg gcttgaattt tagcttaaat aacatgcagt attctaacca gcaattccag cctgttatgg ctaactaa
Molecular Weight
38,155 Da
OMIM
605523
Vector
pENTR223.1 or pUC
Clone Sequence Report
Provided with product shipment
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of TOB1 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for TOB1. It may not necessarily be applicable to this product.

NCBI GI #
21618646
NCBI GeneID
10140
NCBI Accession #
BC031406
UniProt Secondary Accession #
Q4KMQ0; B2R9T0; D3DTY3
UniProt Related Accession #
P50616
NCBI Official Full Name
Homo sapiens transducer of ERBB2, 1, mRNA
NCBI Official Synonym Full Names
transducer of ERBB2, 1
NCBI Official Symbol
TOB1
NCBI Official Synonym Symbols
TOB; TROB; APRO5; APRO6; PIG49; TROB1
UniProt Protein Name
Protein Tob1
UniProt Synonym Protein Names
Transducer of erbB-2 1
Protein Family
Protein
UniProt Gene Name
TOB1
UniProt Synonym Gene Names
TOB; TROB1
UniProt Entry Name
TOB1_HUMAN
NCBI Protein Information
protein Tob1

NCBI Summary for TOB1

This gene encodes a member of the transducer of erbB-2 /B-cell translocation gene protein family. Members of this family are anti-proliferative factors that have the potential to regulate cell growth. The encoded protein may function as a tumor suppressor. Alternate splicing results in multiple transcript variants. [provided by RefSeq, Aug 2011]
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UniProt Comments for TOB1

TOB1: Anti-proliferative protein that interacts with the erbB- 2 receptor tyrosine kinase. May physically and/or functionally interact with protein-tyrosine kinase receptors. Belongs to the BTG family.

Protein type: Cell cycle regulation; Adaptor/scaffold

Chromosomal Location of Human Ortholog: 17q21

Cellular Component: CCR4-NOT complex

Molecular Function: protein binding; receptor tyrosine kinase binding; SH3/SH2 adaptor activity

Biological Process: negative regulation of cell proliferation; negative regulation of translation
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Research Articles on TOB1

1. Reduced TOB1 expression in gastric adenocarcinoma is associated with the extent of differentiation and the TNM stage of gastric cancer.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with TOB1 cdna clone

 Products by Pathway  Pathway Diagram
 BMP Signalling And Regulation Pathway antibodies  BMP Signalling And Regulation Pathway Diagram
 Diurnally Regulated Genes With Circadian Orthologs Pathway antibodies  Diurnally Regulated Genes With Circadian Orthologs Pathway Diagram
 RNA Degradation Pathway antibodies  RNA Degradation Pathway Diagram
 RNA Degradation Pathway antibodies  RNA Degradation Pathway Diagram

Diseases associated with TOB1 cdna clone

 Disease Name  Pubmed Publications
 Neoplasms Antibodies  >25 publications with TOB1 and Neoplasms
 Carcinoma Antibodies  >14 publications with TOB1 and Carcinoma
 Breast Neoplasms Antibodies  >8 publications with TOB1 and Breast Neoplasms
 Lung Neoplasms Antibodies  >5 publications with TOB1 and Lung Neoplasms
 Adenocarcinoma Antibodies  >5 publications with TOB1 and Adenocarcinoma
 Lung Diseases Antibodies  >4 publications with TOB1 and Lung Diseases
 Kidney Diseases Antibodies  >2 publications with TOB1 and Kidney Diseases
 Carcinoma, Squamous Cell Antibodies  >2 publications with TOB1 and Carcinoma, Squamous Cell
 Inflammation Antibodies  >2 publications with TOB1 and Inflammation
 Liver Neoplasms, Experimental Antibodies  >1 publications with TOB1 and Liver Neoplasms, Experimental

Organs/Tissues associated with TOB1 cdna clone

 Organ/Tissue Name  Pubmed Publications
 Lung Antibodies  >11 publications with TOB1 and Lung
 Kidney Antibodies  >5 publications with TOB1 and Kidney
 Embryonic Tissue Antibodies  >4 publications with TOB1 and Embryonic Tissue
 Liver Antibodies  >2 publications with TOB1 and Liver
 Thyroid Antibodies  >2 publications with TOB1 and Thyroid
 Lymph Node Antibodies  >2 publications with TOB1 and Lymph Node
 Intestine Antibodies  >2 publications with TOB1 and Intestine
 Prostate Antibodies  >2 publications with TOB1 and Prostate
 Stomach Antibodies  >2 publications with TOB1 and Stomach
 Skin Antibodies  >1 publications with TOB1 and Skin
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