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VTCN1 cDNA Clone – V-Set Domain Containing T Cell Activation Inhibitor 1 (Human)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1275775

MBS1275775 is a cDNA clone targeting VTCN1. More details

$235 / 0.01 mg Plasmid + 0.2 mL Glycerol-Stock +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
VTCN1, cDNA Clone
Full Product Name
VTCN1 cDNA Clone
Product Gene Name
Sequence
atgttcagag gccggacagc agtgtttgct gatcaagtga tagttggcaa tgcctctttg cggctgaaaa acgtgcaact cacagatgct ggcacctaca aatgttatat catcacttct aaaggcaagg ggaatgctaa ccttgagtat aaaactggag ccttcagcat gccggaagtg aatgtggact ataatgccag ctcagagacc ttgcggtgtg aggctccccg atggttcccc cagcccacag tggtctgggc atcccaagtt gaccagggag ccaacttctc ggaagtctcc aataccagct ttgagctgaa ctctgagaat gtgaccatga aggttgtgtc tgtgctctac aatgttacga tcaacaacac atactcctgt atgattgaaa atgacattgc caaagcaaca ggggatatca aagtgacaga atcggagatc aaaaggcgga gtcacctaca gctgctaaac tcaaaggctt ctctgtgtgt ctcttctttc tttgccatca gctgggcact tctgcctctc agcccttacc tgatgctaaa ataa
Molecular Weight
20,743 Da
OMIM
608162
Vector
pENTR223.1 or pUC
Clone Sequence Report
Provided with product shipment
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.

Other Notes

Small volumes of VTCN1 cdna clone vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for VTCN1. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Secondary Accession #
UniProt Related Accession #
NCBI Official Full Name
Homo sapiens V-set domain containing T cell activation inhibitor 1, mRNA
NCBI Official Synonym Full Names
V-set domain containing T cell activation inhibitor 1
NCBI Official Symbol
VTCN1
NCBI Official Synonym Symbols
B7X; B7H4; B7S1; B7-H4; B7h.5; VCTN1; PRO1291
UniProt Protein Name
V-set domain-containing T-cell activation inhibitor 1
UniProt Synonym Protein Names
B7 homolog 4; B7-H4; B7h.5; Immune costimulatory protein B7-H4; Protein B7S1; T-cell costimulatory molecule B7x
UniProt Gene Name
VTCN1
UniProt Synonym Gene Names
B7-H4
UniProt Entry Name
VTCN1_HUMAN
NCBI Protein Information
V-set domain-containing T-cell activation inhibitor 1

NCBI Summary for VTCN1

This gene encodes a protein belonging to the B7 costimulatory protein family. Proteins in this family are present on the surface of antigen-presenting cells and interact with ligand bound to receptors on the surface of T cells. Studies have shown that high levels of the encoded protein has been correlated with tumor progression. A pseudogene of this gene is located on chromosome 20. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]
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UniProt Comments for VTCN1

VTCN1: Negatively regulates T-cell-mediated immune response by inhibiting T-cell activation, proliferation, cytokine production and development of cytotoxicity. When expressed on the cell surface of tumor macrophages, plays an important role, together with regulatory T-cells (Treg), in the suppression of tumor- associated antigen-specific T-cell immunity. Involved in promoting epithelial cell transformation. Belongs to the immunoglobulin superfamily. BTN/MOG family. 3 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral

Chromosomal Location of Human Ortholog: 1p13.1
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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