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Fetuin A (FETUA) Mouse Recombinant Protein

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS8305245

Recombinant Mouse Fetuin A Protein is produced by mammalian expression system and the target gene encoding Ala19-Ile345 is expressed with a 10His tag at the N-terminus. More details

$235 / 0.01 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Fetuin A (FETUA), Recombinant Protein
Full Product Name
Recombinant Mouse Fetuin A Protein
Product Gene Name
FETUA recombinant protein
Product Synonym Gene Name
AHSG
Product Synonym Names
Alpha-2-HS-glycoprotein; Alpha-2-Z-globulin; Ba-alpha-2-glycoprotein; Fetuin-A
Sequence
APQGTGLGFR ELACDDPEAE QVALLAVDYL NNHLLQGFKQ VLNQIDKVKV WSRRPFGVVY EMEVDTLETT CHALDPTPLA NCSVRQLTEH AVEGDCDFHI LKQDGQFRVM HTQCHSTPDS AEDVRKLCPR CPLLTPFNDT NVVHTVNTAL AAFNTQNNGT YFKLVEISRA QNVPLPVSTL VEFVIAATDC TAKEVTDPAK CNLLAEKQHG FCKANLMHNL GGEEVSVACK LFQTQPQPAN ANAVGPVPTA NAALPADPPA SVVVGPVVVP RGLSDHRTYH DLRHAFSPVA SVESASGETL HSPKVGQPGA AGPVSPMCPG RIRHFKIHHH HHHHHHH
Host
Human Cells
Form/Format
Lyophilized from a 0.2 mum filtered solution of 20mM Tris, 150mM NaCl, pH7.5.
Purity/Purification
>95% as determined by reducing SDS-PAGE
Preparation and Storage
Lyophilized protein should be stored at -20 degree C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 2-8 degree C for 2-7 days. Aliquots of reconstituted samples are stable at -20 degree C for 3 months.
3D Structure
ModBase 3D Structure for P29699
Endotoxin
Less than 0.1 ng/ug (1 IEU/ug) as determined by LAL test.
Applications Tested/Suitable for FETUA recombinant protein
ELISA (EIA), Western Blot (WB), SDS-PAGE

Other Notes

Small volumes of FETUA recombinant protein vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for FETUA purchase

MBS8305245 is a recombinant protein targeting FETUA. Also known as Recombinant Mouse Fetuin A Protein. Host: Human Cells.

Additional Details

NCBI/Uniprot data below describe general gene information for FETUA. It may not necessarily be applicable to this product.

NCBI GI #
7304875
NCBI GeneID
11625
NCBI Accession #
NP_038493.1
UniProt Primary Accession #
P29699
UniProt Related Accession #
P29699
GenBank Nucleotide #
NP_038493.1
NCBI Official Full Name
alpha-2-HS-glycoprotein isoform 1
NCBI Official Synonym Full Names
alpha-2-HS-glycoprotein
NCBI Official Symbol
Ahsg
UniProt Protein Name
Alpha-2-HS-glycoprotein
UniProt Synonym Protein Names
Countertrypin; Fetuin-A
Protein Family
Alpha-2-HS-glycoprotein
UniProt Gene Name
Ahsg
UniProt Synonym Gene Names
Fetua
UniProt Entry Name
FETUA_MOUSE
NCBI Protein Information
alpha-2-HS-glycoprotein

UniProt Comments for FETUA

FETUA: Promotes endocytosis, possesses opsonic properties and influences the mineral phase of bone. Shows affinity for calcium and barium ions. Alpha-2-HS glycoprotein derives from this precursor, when the connecting peptide is cleaved off. The two chains A and B are held together by a single disulfide bond. Synthesized in liver and selectively concentrated in bone matrix. Secreted in plasma. It is also found in dentin in much higher quantities than other plasma proteins. Belongs to the fetuin family.

Protein type: Secreted; Secreted, signal peptide

Cellular Component: extracellular matrix; extracellular space; protein complex

Molecular Function: endopeptidase inhibitor activity; receptor signaling protein tyrosine kinase inhibitor activity

Biological Process: acute-phase response; male gonad development; negative regulation of bone mineralization; negative regulation of cell growth; negative regulation of insulin receptor signaling pathway; ossification; positive regulation of bone resorption; positive regulation of phagocytosis; protein complex assembly; regulation of inflammatory response
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Research Articles on FETUA

1. both FGF23 and Fetuin-A are present and strictly linked to each other in MSCs with FGF23 driving Fetuin-A production. This mechanism suggests a role for these two proteins in the osteoblast differentiation.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with FETUA recombinant protein

 Products by Pathway  Pathway Diagram
 Hemostasis Pathway antibodies  Hemostasis Pathway Diagram
 Immune System Pathway antibodies  Immune System Pathway Diagram
 Innate Immune System Pathway antibodies  Innate Immune System Pathway Diagram
 Neutrophil Degranulation Pathway antibodies  Neutrophil Degranulation Pathway Diagram
 Platelet Activation, Signaling And Aggregation Pathway antibodies  Platelet Activation, Signaling And Aggregation Pathway Diagram
 Platelet Degranulation Pathway antibodies  Platelet Degranulation Pathway Diagram
 Response To Elevated Platelet Cytosolic Ca2+ Pathway antibodies  Response To Elevated Platelet Cytosolic Ca2+ Pathway Diagram
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