ACOT4 Blocking Peptide – Cat# MBS8219936

ACOT4 Blocking Peptide – >85% Purity

Name: ACOT4 Blocking Peptide; >85% Purity; MyBioSource
Brand: MyBioSource
SKU: MBS8219936
Price: 230 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS8219936

MBS8219936 is a blocking peptide targeting ACOT4. Reactive in Human. Host: Synthetic. The peptide is used to block Anti-ACOT4 Antibody reactivity. More details

$230 / 1 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

ACOT4, Blocking Peptide

Full Product Name

ACOT4 Blocking Peptide

Product Gene Name

ACOT4 blocking peptide

Product Synonym Names

PTE2B; PTEIB; Acyl-coenzyme A thioesterase 4; Acyl-CoA thioesterase 4; PTE-2b; Peroxisomal acyl coenzyme A thioester hydrolase Ib; Peroxisomal long-chain acyl-CoA thioesterase Ib; PTE-Ib

Host

Synthetic

Species Reactivity

Human

Form/Format

Lyophilized powder

Purity/Purification

>85%

Preparation and Storage

Shipped at 4 degree C. Store at -20 degree C for one year.

Antibody/Peptide Pairs

ACOT4 peptide (MBS8219936) is used for blocking the activity of ACOT4 antibody (MBS8222733)

Molecular Weight

46,327 Da

OMIM

614314

Quality Control

The quality of the peptide was evaluated by reversed-phase HPLC and by mass spectrometry.

Directions for Use

Blocking Peptide to the diluted primary antibody in a molar ratio of 10:1 (peptide to antibody) and incubate the mixture at 4 degree C for overnight or at room temperature for 2 hours.

Applications Tested/Suitable for ACOT4 blocking peptide

Blocking (BL)

Other Notes

Small volumes of ACOT4 blocking peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for ACOT4. It may not necessarily be applicable to this product.

NCBI GI #

187761341

NCBI GeneID

122970

NCBI Accession #

NP_689544.3

UniProt Primary Accession #

Q8N9L9

UniProt Secondary Accession #

Q17RF4; Q5BKT6; Q86TX0; Q86TX1; Q96N88

UniProt Related Accession #

Q8N9L9

GenBank Nucleotide #

NM_152331.3

NCBI Official Full Name

acyl-coenzyme A thioesterase 4

NCBI Official Synonym Full Names

acyl-CoA thioesterase 4

NCBI Official Symbol

ACOT4

NCBI Official Synonym Symbols

PTE1B; PTE2B; PTE-Ib

UniProt Protein Name

Acyl-coenzyme A thioesterase 4

UniProt Synonym Protein Names

PTE-2b; Peroxisomal acyl coenzyme A thioester hydrolase Ib; Peroxisomal long-chain acyl-CoA thioesterase Ib; PTE-Ib

Protein Family

Acyl-coenzyme A thioesterase

UniProt Gene Name

ACOT4

UniProt Synonym Gene Names

PTE2B; PTEIB; Acyl-CoA thioesterase 4; PTE-Ib

UniProt Entry Name

ACOT4_HUMAN

NCBI Protein Information

acyl-coenzyme A thioesterase 4

UniProt Comments for ACOT4

ACOT4: Acyl-CoA thioesterases are a group of enzymes that catalyze the hydrolysis of acyl-CoAs to the free fatty acid and coenzyme A (CoASH), providing the potential to regulate intracellular levels of acyl-CoAs, free fatty acids and CoASH. Succinyl-CoA thioesterase that also hydrolyzes long chain saturated and unsaturated monocarboxylic acyl-CoAs. Belongs to the C/M/P thioester hydrolase family.

Protein type: Hydrolase; Lipid Metabolism - unsaturated fatty acid biosynthesis; EC 3.1.2.2

Chromosomal Location of Human Ortholog: 14q24.3

Cellular Component: peroxisome

Molecular Function: acyl-CoA hydrolase activity; succinyl-CoA hydrolase activity; palmitoyl-CoA hydrolase activity; receptor binding

Biological Process: dicarboxylic acid metabolic process; acyl-CoA metabolic process; short-chain fatty acid metabolic process; succinyl-CoA metabolic process; very-long-chain fatty acid metabolic process; saturated monocarboxylic acid metabolic process; long-chain fatty acid metabolic process; dicarboxylic acid catabolic process; unsaturated monocarboxylic acid metabolic process; butyrate metabolic process

Research Articles on ACOT4

1. ACOT4 and ACOT8 are responsible for the termination of beta-oxidation of dicarboxylic acids of medium-chain length with the concomitant release of the corresponding free acids

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with ACOT4 blocking peptide

Reference Product	PubMed Publications
ACOT8 blocking peptide	>2 publications with ACOT4 and ACOT8
HNF4A blocking peptide	>1 publications with ACOT4 and HNF4A

Pathways associated with ACOT4 blocking peptide

Products by Pathway	Pathway Diagram
Biosynthesis Of Unsaturated Fatty Acids Pathway antibodies	Biosynthesis Of Unsaturated Fatty Acids Pathway Diagram
Biosynthesis Of Unsaturated Fatty Acids Pathway antibodies	Biosynthesis Of Unsaturated Fatty Acids Pathway Diagram
Fatty Acid Elongation Pathway antibodies	Fatty Acid Elongation Pathway Diagram
Fatty Acid Elongation Pathway antibodies	Fatty Acid Elongation Pathway Diagram
Metabolic Pathways antibodies	Metabolic Pathways Diagram
Oleate Biosynthesis Pathway antibodies	Oleate Biosynthesis Pathway Diagram
Oleate Biosynthesis II (animals And Fungi) Pathway antibodies	Oleate Biosynthesis II (animals And Fungi) Pathway Diagram
Palmitate Biosynthesis Pathway antibodies	Palmitate Biosynthesis Pathway Diagram
Palmitate Biosynthesis I (animals And Fungi) Pathway antibodies	Palmitate Biosynthesis I (animals And Fungi) Pathway Diagram
Stearate Biosynthesis Pathway antibodies	Stearate Biosynthesis Pathway Diagram

Diseases associated with ACOT4 blocking peptide

Disease Name	Pubmed Publications
Fatty Liver Antibodies	>2 publications with ACOT4 and Fatty Liver
Liver Diseases Antibodies	>1 publications with ACOT4 and Liver Diseases

Organs/Tissues associated with ACOT4 blocking peptide

Organ/Tissue Name	Pubmed Publications
Lung Antibodies	>1 publications with ACOT4 and Lung
Adipose Tissue Antibodies	>1 publications with ACOT4 and Adipose Tissue
Kidney Antibodies	>1 publications with ACOT4 and Kidney