ELP4 Peptide - C-Terminal Region Blocking Peptide

Name: ELP4 Peptide - C-Terminal Region Blocking Peptide; MyBioSource
Brand: MyBioSource
SKU: MBS3244325
Price: 195 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS3244325

This is a synthetic peptide designed for use in combination with anti-ELP4 Antibody, madeTarget Description: This gene encodes a component of the six subunit elongator complex, a histone acetyltransferase complex that associates directly with RNA polymerase… More details

$195 / 0.1 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

ELP4, Blocking Peptide

Full Product Name

ELP4 Peptide - C-terminal region

Product Gene Name

ELP4 blocking peptide

Product Synonym Gene Name

ELP4;C11orf19;PAXNEB;

Sequence

Synthetic peptide located within the following region: VEPCSLTPGY TKLLQFIQNI IYEEGFDGSN PQKKQRNILR IGIQNLGSPL

Species Reactivity

Human

Form/Format

Lyophilized powder

Preparation and Storage

Add 100ul of sterile PBS. Final peptide concentration is 1 mg/ml in PBS. For longer periods of storage, store at -20 degree C. Avoid repeat freeze-thaw cycles.

Antibody/Peptide Pairs

ELP4 peptide (MBS3244325) is used for blocking the activity of ELP4 antibody (MBS3219445)

Molecular Weight

46kDa

OMIM

606985

Product Categories/Family for ELP4 blocking peptide

Peptide

Applications Tested/Suitable for ELP4 blocking peptide

Western Blot (WB)

Other Notes

Small volumes of ELP4 blocking peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for ELP4 purchase

MBS3244325 is a blocking peptide targeting ELP4. Also known as ELP4 Peptide - C-terminal region. Reactive in Human.

Additional Details

NCBI/Uniprot data below describe general gene information for ELP4. It may not necessarily be applicable to this product.

NCBI GI #

570359562

NCBI GeneID

26610

NCBI Accession #

NP_061913

UniProt Primary Accession #

Q96EB1

UniProt Related Accession #

Q96EB1

GenBank Nucleotide #

NM_001288725.1

NCBI Official Full Name

elongator complex protein 4 isoform 2

NCBI Official Synonym Full Names

elongator acetyltransferase complex subunit 4

NCBI Official Symbol

ELP4

NCBI Official Synonym Symbols

AN; AN2; hELP4; PAXNEB; PAX6NEB; C11orf19; dJ68P15A.1

UniProt Protein Name

Elongator complex protein 4

UniProt Synonym Protein Names

PAX6 neighbor gene protein

Protein Family

Elongator complex protein

UniProt Gene Name

ELP4

UniProt Synonym Gene Names

C11orf19; PAXNEB; hELP4

UniProt Entry Name

ELP4_HUMAN

NCBI Protein Information

elongator complex protein 4

NCBI Summary for ELP4

This gene encodes a component of the six subunit elongator complex, a histone acetyltransferase complex that associates directly with RNA polymerase II during transcriptional elongation. The human gene can partially complement sensitivity phenotypes of yeast ELP4 deletion mutants. This gene has also been associated with Rolandic epilepsy. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2013]

UniProt Comments for ELP4

ELP4: Acts as subunit of the RNA polymerase II elongator complex, which is a histone acetyltransferase component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation. Elongator may play a role in chromatin remodeling and is involved in acetylation of histones H3 and probably H4. Belongs to the ELP4 family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Unknown function

Chromosomal Location of Human Ortholog: 11p13

Cellular Component: cytoplasm; Elongator holoenzyme complex; histone acetyltransferase complex; nucleoplasm; transcription elongation factor complex

Molecular Function: histone acetyltransferase activity; phosphorylase kinase regulator activity; protein binding

Biological Process: regulation of transcription from RNA polymerase II promoter; RNA elongation from RNA polymerase II promoter

Disease: Aniridia; Aniridia 2

Research Articles on ELP4

1. Our results suggest that ELP4 deletions are highly likely to be pathogenic, predisposing to a range of neurodevelopmental phenotypes from ASD to language impairment and epilepsy.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with ELP4 blocking peptide

Reference Product	PubMed Publications
ELP6 blocking peptide	>12 publications with ELP4 and ELP6
ELP3 blocking peptide	>10 publications with ELP4 and ELP3
ELP5 blocking peptide	>9 publications with ELP4 and ELP5
ELP2 blocking peptide	>9 publications with ELP4 and ELP2

Pathways associated with ELP4 blocking peptide

Products by Pathway	Pathway Diagram
Chromatin Modifying Enzymes Pathway antibodies	Chromatin Modifying Enzymes Pathway Diagram
Chromatin Organization Pathway antibodies	Chromatin Organization Pathway Diagram
HATs Acetylate Histones Pathway antibodies	HATs Acetylate Histones Pathway Diagram

Diseases associated with ELP4 blocking peptide

Disease Name	Pubmed Publications
Congenital Abnormalities Antibodies	>7 publications with ELP4 and Congenital Abnormalities
Epilepsy, Temporal Lobe Antibodies	>1 publications with ELP4 and Epilepsy, Temporal Lobe
Kidney Diseases Antibodies	>1 publications with ELP4 and Kidney Diseases
Abnormalities, Multiple Antibodies	>1 publications with ELP4 and Abnormalities, Multiple
Neurobehavioral Manifestations Antibodies	>1 publications with ELP4 and Neurobehavioral Manifestations

Organs/Tissues associated with ELP4 blocking peptide

Organ/Tissue Name	Pubmed Publications
Eye Antibodies	>9 publications with ELP4 and Eye
Brain Antibodies	>8 publications with ELP4 and Brain
Blood Antibodies	>6 publications with ELP4 and Blood
Skin Antibodies	>1 publications with ELP4 and Skin
Pancreas Antibodies	>1 publications with ELP4 and Pancreas
Embryonic Tissue Antibodies	>1 publications with ELP4 and Embryonic Tissue
Kidney Antibodies	>1 publications with ELP4 and Kidney