NDUFA4 Blocking Peptide – Cat# MBS824316

NDUFA4 Blocking Peptide – >85% Purity

Name: NDUFA4 Blocking Peptide; >85% Purity; MyBioSource
Brand: MyBioSource
SKU: MBS824316
Price: 230 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS824316

MBS824316 is a blocking peptide targeting NDUFA4. Reactive in Human. Host: Synthetic. The peptide is used to block Anti-NDUFA4 Antibody reactivity. More details

$230 / 1 mg +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

NDUFA4, Blocking Peptide

Full Product Name

NDUFA4 Blocking Peptide

Product Gene Name

NDUFA4 blocking peptide

Product Synonym Names

NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 4; Complex I-MLRQ; CI-MLRQ; NADH-ubiquinone oxidoreductase MLRQ subunit

Host

Synthetic

Species Reactivity

Human

Form/Format

Lyophilized powder

Purity/Purification

>85%

Preparation and Storage

Shipped at 4 degree C. Store at -20 degree C for one year.

Antibody/Peptide Pairs

NDUFA4 peptide (MBS824316) is used for blocking the activity of NDUFA4 antibody (MBS821132)

Molecular Weight

9,370 Da

OMIM

phenotype 603833

Quality Control

The quality of the peptide was evaluated by reversed-phase HPLC and by mass spectrometry.

Applications Tested/Suitable for NDUFA4 blocking peptide

Blocking (BL)

Application Notes for NDUFA4 blocking peptide

Blocking Peptide to the diluted primary antibody in a molar ratio of 10:1 (peptide to antibody) and incubate the mixture at 4 degree C for overnight or at room temperature for 2 hours.

Other Notes

Small volumes of NDUFA4 blocking peptide vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for NDUFA4. It may not necessarily be applicable to this product.

NCBI GI #

4505357

NCBI GeneID

4697

NCBI Accession #

NP_002480.1

UniProt Primary Accession #

O00483

UniProt Secondary Accession #

Q6FHN5; A4D109

UniProt Related Accession #

O00483

GenBank Nucleotide #

NM_002489.3

NCBI Official Full Name

cytochrome c oxidase subunit NDUFA4

NCBI Official Synonym Full Names

NDUFA4, mitochondrial complex associated

NCBI Official Symbol

NDUFA4

NCBI Official Synonym Symbols

MLRQ; CI-9k; CI-MLRQ

UniProt Protein Name

Cytochrome c oxidase subunit NDUFA4

UniProt Synonym Protein Names

Complex I-MLRQ; CI-MLRQ; NADH-ubiquinone oxidoreductase MLRQ subunit

Protein Family

Cytochrome c oxidase

UniProt Gene Name

NDUFA4

UniProt Synonym Gene Names

CI-MLRQ

UniProt Entry Name

NDUA4_HUMAN

NCBI Protein Information

cytochrome c oxidase subunit NDUFA4; complex I-MLRQ; Complex I 9kDa subunit; NADH-ubiquinone oxidoreductase MLRQ subunit; NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, 4, 9kDa; NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 4

NCBI Summary for NDUFA4

The protein encoded by this gene belongs to the complex I 9kDa subunit family. Mammalian complex I of mitochondrial respiratory chain is composed of 45 different subunits. This protein has NADH dehydrogenase activity and oxidoreductase activity. It transfers electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. [provided by RefSeq, Jul 2008]

UniProt Comments for NDUFA4

NDUFA4: Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed to be not involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. Belongs to the complex I NDUFA4 subunit family.

Protein type: Mitochondrial; Oxidoreductase; Energy Metabolism - oxidative phosphorylation; EC 1.6.5.3; EC 1.6.99.3

Chromosomal Location of Human Ortholog: 7p21.3

Cellular Component: mitochondrion; mitochondrial inner membrane; mitochondrial respiratory chain complex IV; mitochondrial respiratory chain complex I

Molecular Function: protein binding; cytochrome-c oxidase activity; NADH dehydrogenase (ubiquinone) activity; protein complex binding

Biological Process: cellular metabolic process; mitochondrial electron transport, NADH to ubiquinone

Research Articles on NDUFA4

1. Findings support reassignment of the NDUFA4 protein to complex IV and suggest that patients with unexplained COX deficiency should be screened for NDUFA4 mutations.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with NDUFA4 blocking peptide

Reference Product	PubMed Publications
NDUFA1 blocking peptide	>2 publications with NDUFA4 and NDUFA1

Pathways associated with NDUFA4 blocking peptide

Products by Pathway	Pathway Diagram
Alzheimer's Disease Pathway antibodies	Alzheimer's Disease Pathway Diagram
Alzheimer's Disease Pathway antibodies	Alzheimer's Disease Pathway Diagram
Electron Transport Chain Pathway antibodies	Electron Transport Chain Pathway Diagram
Huntington's Disease Pathway antibodies	Huntington's Disease Pathway Diagram
Huntington's Disease Pathway antibodies	Huntington's Disease Pathway Diagram
Metabolic Pathways antibodies	Metabolic Pathways Diagram
Metabolism Pathway antibodies	Metabolism Pathway Diagram
NADH Dehydrogenase (ubiquinone) 1 Alpha Subcomplex Pathway antibodies	NADH Dehydrogenase (ubiquinone) 1 Alpha Subcomplex Pathway Diagram
NADH Dehydrogenase (ubiquinone) 1 Alpha Subcomplex Pathway antibodies	NADH Dehydrogenase (ubiquinone) 1 Alpha Subcomplex Pathway Diagram
Non-alcoholic Fatty Liver Disease (NAFLD) Pathway antibodies	Non-alcoholic Fatty Liver Disease (NAFLD) Pathway Diagram

Diseases associated with NDUFA4 blocking peptide

Disease Name	Pubmed Publications
Nervous System Diseases Antibodies	>6 publications with NDUFA4 and Nervous System Diseases
Death Antibodies	>2 publications with NDUFA4 and Death
Cognition Disorders Antibodies	>1 publications with NDUFA4 and Cognition Disorders
Mitochondrial Diseases Antibodies	>1 publications with NDUFA4 and Mitochondrial Diseases

Organs/Tissues associated with NDUFA4 blocking peptide

Organ/Tissue Name	Pubmed Publications
Kidney Antibodies	>1 publications with NDUFA4 and Kidney
Muscle Antibodies	>1 publications with NDUFA4 and Muscle
Liver Antibodies	>1 publications with NDUFA4 and Liver