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CSTF2 Antibody

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS852206

MBS852206 is an antibody targeting CSTF2. Also known as CSTF2 Antibody. Reactive in Human, Mouse. More details

$380 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
CSTF2, Antibody
Full Product Name
CSTF2 Antibody
Product Gene Name
anti-CSTF2 antibody
Product Synonym Names
CF-1 64 kDa; CSTF 64 kDa; CstF-64; cleavage stimulation factor subunit 2; cleavage stimulation factor; 3' pre-RNA; subunit 2; 64kDa; cleavage stimulation factor; 64 kDa; cleavage stimulation factor; 64kDa subunit
Species Reactivity
Human, Mouse
Form/Format
In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Specificity
CSTF2 antibody detects endogenous levels of total CSTF2 protein.
Preparation and Storage
Store at-20 degree C for 1 year.
Molecular Weight
59,251 Da
OMIM
300907
3D Structure
ModBase 3D Structure for P33240
Immunogen
The antiserum was produced against synthesized peptide derived from N-terminal of human CSTF2.

Product Categories/Family for anti-CSTF2 antibody

Autophagy antibody; Cancer; Cardiovascular; Cell Biology; Epigenetics & Nuclear Signaling; Developmental Biologys; Immunology; Drug Discovery Products; Metabolism; Neuroscience; Signal Transduction; Stem Cells
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-CSTF2 antibody
Western Blot (WB), Immunofluorescence (IF), ELISA (EIA)
Application Notes for anti-CSTF2 antibody
WB: 1:500~1:1000
IF: 1:100~1:500
ELISA: 1:10000

Testing Data of anti-CSTF2 antibody

Anti-CSTF2 Antibody – Cat# MBS852206

Western Blot (WB) of anti-CSTF2 antibody

Peptide-+ Western blot analysis of extracts from 293 cells. HepG2 cells and Jurkat cells, using CSTF2 antibody. Immunofluorescence analysis of HeLa cells, using CSTF2 antibody.
Anti-CSTF2 Antibody, Western Blot (WB) – Cat# MBS852206

Product References and Citations for anti-CSTF2 antibody

Takagaki Y., Proc. Natl. Acad. Sci. U.S.A. 89:1403-1407(1992). Ross M.T., Nature 434:325-337(2005). Takagaki Y., Mol. Cell. Biol. 17:3907-3914(1997).

Other Notes

Small volumes of anti-CSTF2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for CSTF2. It may not necessarily be applicable to this product.

NCBI GI #
807201178
NCBI GeneID
1478
NCBI Accession #
NP_001293138.1
UniProt Primary Accession #
P33240
UniProt Secondary Accession #
Q5H951; Q6LA74; Q8N502
UniProt Related Accession #
P33240
GenBank Nucleotide #
NM_001306209.1
NCBI Official Full Name
cleavage stimulation factor subunit 2 isoform 3
NCBI Official Synonym Full Names
cleavage stimulation factor subunit 2
NCBI Official Symbol
CSTF2
NCBI Official Synonym Symbols
CstF-64
UniProt Protein Name
Cleavage stimulation factor subunit 2
UniProt Synonym Protein Names
CF-1 64 kDa subunit; Cleavage stimulation factor 64 kDa subunit; CSTF 64 kDa subunit; CstF-64
Protein Family
Cleavage stimulation factor
UniProt Gene Name
CSTF2
UniProt Synonym Gene Names
CSTF 64 kDa subunit; CstF-64
NCBI Protein Information
cleavage stimulation factor subunit 2

NCBI Summary for CSTF2

This gene encodes a nuclear protein with an RRM (RNA recognition motif) domain. The protein is a member of the cleavage stimulation factor (CSTF) complex that is involved in the 3' end cleavage and polyadenylation of pre-mRNAs. Specifically, this protein binds GU-rich elements within the 3'-untranslated region of mRNAs. [provided by RefSeq, Jul 2008]
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UniProt Comments for CSTF2

One of the multiple factors required for polyadenylation and 3'-end cleavage of mammalian pre-mRNAs. This subunit is directly involved in the binding to pre-mRNAs ().

Research Articles on CSTF2

1. hnRNP H binds to two specific G-runs in exon 5a of ACHE and activates the distal alternative 3 splice site (ss) between exons 5a and 5b. Furthermore, hnRNP H competes for binding of CstF64 to the overlapping binding sites in exon 5a, and suppresses the selection of a cryptic polyadenylation site, which additionally ensures transcription of the distal 3 ss required for the generation of AChET isoform.
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-CSTF2 antibody

 Products by Pathway  Pathway Diagram
 Cleavage Of Growing Transcript In The Termination Region Pathway antibodies  Cleavage Of Growing Transcript In The Termination Region Pathway Diagram
 Gene Expression Pathway antibodies  Gene Expression Pathway Diagram
 Processing Of Capped Intron-Containing Pre-mRNA Pathway antibodies  Processing Of Capped Intron-Containing Pre-mRNA Pathway Diagram
 Processing Of Capped Intronless Pre-mRNA Pathway antibodies  Processing Of Capped Intronless Pre-mRNA Pathway Diagram
 Processing Of Intronless Pre-mRNAs Pathway antibodies  Processing Of Intronless Pre-mRNAs Pathway Diagram
 RNA Polymerase II Transcription Pathway antibodies  RNA Polymerase II Transcription Pathway Diagram
 RNA Polymerase II Transcription Termination Pathway antibodies  RNA Polymerase II Transcription Termination Pathway Diagram
 MRNA 3'-end Processing Pathway antibodies  MRNA 3'-end Processing Pathway Diagram
 MRNA Splicing Pathway antibodies  MRNA Splicing Pathway Diagram
 MRNA Splicing - Major Pathway antibodies  MRNA Splicing - Major Pathway Diagram

Diseases associated with anti-CSTF2 antibody

 Disease Name  Pubmed Publications
 Hyperplasia Antibodies  >1 publications with CSTF2 and Hyperplasia
 Congenital Abnormalities Antibodies  >1 publications with CSTF2 and Congenital Abnormalities
 Necrosis Antibodies  >1 publications with CSTF2 and Necrosis

Organs/Tissues associated with anti-CSTF2 antibody

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >3 publications with CSTF2 and Brain
 Testis Antibodies  >2 publications with CSTF2 and Testis
 Liver Antibodies  >1 publications with CSTF2 and Liver
 Heart Antibodies  >1 publications with CSTF2 and Heart
 Muscle Antibodies  >1 publications with CSTF2 and Muscle
 Embryonic Tissue Antibodies  >1 publications with CSTF2 and Embryonic Tissue
 Lung Antibodies  >1 publications with CSTF2 and Lung
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