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DCP1A Antibody

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS856072

MBS856072 is an antibody targeting DCP1A. Also known as DCP1A Antibody. Reactive in Human, Mouse. More details

$380 / 0.1 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
DCP1A, Antibody
Full Product Name
DCP1A Antibody
Product Gene Name
anti-DCP1A antibody
Product Synonym Names
mRNA-decapping enzyme 1A; EC 3.-.-.-; Transcription factor SMIF; Smad4-interacting transcriptional co-activator; DCP1A; SMIF
Species Reactivity
Human, Mouse
Form/Format
In phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purity/Purification
Affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Specificity
DCP1A antibody detects endogenous levels of total DCP1A protein.
Preparation and Storage
Store at-20 degree C for 1 year.
Molecular Weight
59,361 Da
OMIM
607010
3D Structure
ModBase 3D Structure for Q9NPI6
Immunogen
The antiserum was produced against synthesized peptide derived from internal of human DCP1A.

Product Categories/Family for anti-DCP1A antibody

Autophagy antibody; Cancer; Cardiovascular; Cell Biology; Epigenetics & Nuclear Signaling; Developmental Biologys; Immunology; Drug Discovery Products; Metabolism; Neuroscience; Signal Transduction; Stem Cells
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-DCP1A antibody
Western Blot (WB), ELISA (EIA)
Application Notes for anti-DCP1A antibody
WB: 1:500~1:1000
ELISA: 1:20000

Western Blot (WB) of anti-DCP1A antibody

Western blot analysis of extracts from Jurkat cells, using DCP1A antibody.
Anti-DCP1A Antibody – Cat# MBS856072

Product References and Citations for anti-DCP1A antibody

Lykke-Andersen J., Mol. Cell. Biol. 22:8114-8121(2002). Bai R.-Y., Nat. Cell Biol. 4:181-190(2002). Ota T., Nat. Genet. 36:40-45(2004).

Other Notes

Small volumes of anti-DCP1A antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for DCP1A. It may not necessarily be applicable to this product.

NCBI GI #
589269220
NCBI GeneID
55802
NCBI Accession #
NP_001277133.1
UniProt Primary Accession #
Q9NPI6
UniProt Secondary Accession #
B4DHN9; U3KQM8
UniProt Related Accession #
Q9NPI6
GenBank Nucleotide #
NM_001290204.1
NCBI Official Full Name
mRNA-decapping enzyme 1A isoform b
NCBI Official Synonym Full Names
decapping mRNA 1A
NCBI Official Symbol
DCP1A
NCBI Official Synonym Symbols
SMIF; SMAD4IP1; HSA275986; Nbla00360
UniProt Protein Name
mRNA-decapping enzyme 1A
UniProt Synonym Protein Names
Smad4-interacting transcriptional co-activator; Transcription factor SMIF
Protein Family
mRNA-decapping enzyme
UniProt Gene Name
DCP1A
UniProt Synonym Gene Names
SMIF
NCBI Protein Information
mRNA-decapping enzyme 1A

NCBI Summary for DCP1A

Decapping is a key step in general and regulated mRNA decay. The protein encoded by this gene is a decapping enzyme. This protein and another decapping enzyme form a decapping complex, which interacts with the nonsense-mediated decay factor hUpf1 and may be recruited to mRNAs containing premature termination codons. This protein also participates in the TGF-beta signaling pathway. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Feb 2014]
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UniProt Comments for DCP1A

Necessary for the degradation of mRNAs, both in normal mRNA turnover and in nonsense-mediated mRNA decay. Removes the 7-methyl guanine cap structure from mRNA molecules, yielding a 5'-phosphorylated mRNA fragment and 7m-GDP. Contributes to the transactivation of target genes after stimulation by TGFB1.
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Research Articles on DCP1A

1. The results suggest that overexpressed Dcp1a and GW182 can form different cytoplasmic aggregates and play distinct biological roles in the miRNA pathway.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with anti-DCP1A antibody

 Products by Pathway  Pathway Diagram
 Butyrate Response Factor 1 (BRF1) Binds And Destabilizes MRNA Pathway antibodies  Butyrate Response Factor 1 (BRF1) Binds And Destabilizes MRNA Pathway Diagram
 Deadenylation-dependent MRNA Decay Pathway antibodies  Deadenylation-dependent MRNA Decay Pathway Diagram
 Decapping Complex Pathway antibodies  Decapping Complex Pathway Diagram
 Decapping Complex Pathway antibodies  Decapping Complex Pathway Diagram
 Gene Expression Pathway antibodies  Gene Expression Pathway Diagram
 RNA Degradation Pathway antibodies  RNA Degradation Pathway Diagram
 RNA Degradation Pathway antibodies  RNA Degradation Pathway Diagram
 Regulation Of MRNA Stability By Proteins That Bind AU-rich Elements Pathway antibodies  Regulation Of MRNA Stability By Proteins That Bind AU-rich Elements Pathway Diagram
 Regulation Of Nuclear SMAD2/3 Signaling Pathway antibodies  Regulation Of Nuclear SMAD2/3 Signaling Pathway Diagram
 TGF-beta Receptor Signaling Pathway antibodies  TGF-beta Receptor Signaling Pathway Diagram

Diseases associated with anti-DCP1A antibody

 Disease Name  Pubmed Publications
 Necrosis Antibodies  >2 publications with DCP1A and Necrosis
 Neurobehavioral Manifestations Antibodies  >1 publications with DCP1A and Neurobehavioral Manifestations
 Congenital Abnormalities Antibodies  >1 publications with DCP1A and Congenital Abnormalities
 Kidney Diseases Antibodies  >1 publications with DCP1A and Kidney Diseases

Organs/Tissues associated with anti-DCP1A antibody

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >4 publications with DCP1A and Brain
 Blood Antibodies  >3 publications with DCP1A and Blood
 Liver Antibodies  >3 publications with DCP1A and Liver
 Kidney Antibodies  >2 publications with DCP1A and Kidney
 Ovary Antibodies  >2 publications with DCP1A and Ovary
 Heart Antibodies  >2 publications with DCP1A and Heart
 Stomach Antibodies  >1 publications with DCP1A and Stomach
 Nerve Antibodies  >1 publications with DCP1A and Nerve
 Bone Antibodies  >1 publications with DCP1A and Bone
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