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SLAIN2 siRNA – SLAIN Motif-Containing Protein 2 (Human)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS8227712

MBS8227712 is an siRNA targeting SLAIN2. Also known as SLAIN2 siRNA (Human). Reactive in Human. Host: Synthetic. siRNA to inhibit SLAIN2 expression using RNA interference More details

$480 / 15 nmol +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
SLAIN2, siRNA
Full Product Name
SLAIN2 siRNA (Human)
Product Gene Name
Product Synonym Names
KIAA1458; SLAIN motif-containing protein 2
Host
Synthetic
Species Reactivity
Human
Form/Format
Lyophilized powder
Purity/Purification
> 97%
Specificity
SLAIN2 siRNA (Human) is a target-specific 19-23 nt siRNA oligo duplexes designed to knock down gene expression.
Preparation and Storage
Shipped at 4 degree C. Store at -20 degree C for one year.
Molecular Weight
62,543 Da
OMIM
610492
3D Structure
ModBase 3D Structure for Q9P270
Negative Control
siRNA Negative Control (Catalog# MBS8241404) is a non-targeting 21 nt siRNA recommended as a negative control for experiments using targeted siRNA transfection.
Quality Control
Oligonucleotide synthesis is monitored base by base through trityl analysis to ensure appropriate coupling efficiency. The oligo is subsequently purified by affinity-solid phase extraction. The annealed RNA duplex is further analyzed by mass spectrometry to verify the exact composition of the duplex. Each lot is compared to the previous lot by mass spectrometry to ensure maximum lot-to-lot consistency.
Directions for Use
We recommends transfection with 100 nM siRNA 48 to 72 hours prior to cell lysis. Before resuspending, briefly centrifuge the tube to ensure the lyophilized siRNA is at the bottom of the tube. Resuspend the siRNA oligos to an appropriate concentration with DEPC water. For each vial, suitable for 250 transfections in 24 well plate (20 pmol for each well).
Components
We offer pre-designed sets of 3 different target-specific siRNA oligo duplexes of human SLAIN2 gene. Each vial contains 5 nmol of lyophilized siRNA. The duplexes can be transfected individually or pooled together to achieve knockdown of the target gene, which is most commonly assessed by qPCR or western blot. Our siRNA oligos are also chemically modified (2'-OMe) at no extra charge for increased stability and enhanced knockdown in vitro and in vivo.
Applications Tested/Suitable for SLAIN2 sirna
RNA Interference (RNAi)

Other Notes

Small volumes of SLAIN2 sirna vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for SLAIN2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
SLAIN motif-containing protein 2
NCBI Official Synonym Full Names
SLAIN motif family, member 2
NCBI Official Symbol
SLAIN2
NCBI Official Synonym Symbols
KIAA1458
UniProt Protein Name
SLAIN motif-containing protein 2
UniProt Gene Name
SLAIN2
UniProt Synonym Gene Names
KIAA1458
UniProt Entry Name
SLAI2_HUMAN
NCBI Protein Information
SLAIN motif-containing protein 2

UniProt Comments for SLAIN2

SLAIN2: Binds to the plus end of microtubules and regulates microtubule dynamics and microtubule organization. Promotes cytoplasmic microtubule nucleation and elongation. Required for normal structure of the microtubule cytoskeleton during interphase. Belongs to the SLAIN motif-containing family.

Protein type: Unknown function

Chromosomal Location of Human Ortholog: 4p11

Cellular Component: microtubule cytoskeleton; nucleoplasm; centrosome; cytoplasm; nucleolus

Molecular Function: protein binding

Biological Process: positive regulation of microtubule polymerization; microtubule nucleation; cytoplasmic microtubule organization and biogenesis
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with SLAIN2 sirna

 Reference Product  PubMed Publications
 CKAP5 sirna  >2 publications with SLAIN2 and CKAP5

Organs/Tissues associated with SLAIN2 sirna

 Organ/Tissue Name  Pubmed Publications
 Brain Antibodies  >1 publications with SLAIN2 and Brain
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