ZFP90 siRNA – Zinc Finger Protein 90 Homolog Isoform 1 (Human)

Name: ZFP90 siRNA; Human; MyBioSource
Brand: MyBioSource
SKU: MBS8201476
Price: 480 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS8201476

MBS8201476 is an siRNA targeting ZFP90. Also known as ZFP90 siRNA (Human). Reactive in Human. Host: Synthetic. siRNA to inhibit ZFP90 expression using RNA interference More details

$480 / 15 nmol +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

ZFP90, siRNA

Full Product Name

ZFP90 siRNA (Human)

Product Gene Name

ZFP90 sirna

Product Synonym Names

KIAA1954; ZNF756; Zinc finger protein 90 homolog; Zfp-90; Zinc finger protein 756

Host

Synthetic

Species Reactivity

Human

Form/Format

Lyophilized powder

Purity/Purification

> 97%

Specificity

ZFP90 siRNA (Human) is a target-specific 19-23 nt siRNA oligo duplexes designed to knock down gene expression.

Preparation and Storage

Shipped at 4 degree C. Store at -20 degree C for one year.

Molecular Weight

13,006 Da

OMIM

609451

3D Structure

ModBase 3D Structure for Q8TF47

Negative Control

siRNA Negative Control (Catalog# MBS8241404) is a non-targeting 21 nt siRNA recommended as a negative control for experiments using targeted siRNA transfection.

Quality Control

Oligonucleotide synthesis is monitored base by base through trityl analysis to ensure appropriate coupling efficiency. The oligo is subsequently purified by affinity-solid phase extraction. The annealed RNA duplex is further analyzed by mass spectrometry to verify the exact composition of the duplex. Each lot is compared to the previous lot by mass spectrometry to ensure maximum lot-to-lot consistency.

Directions for Use

We recommends transfection with 100 nM siRNA 48 to 72 hours prior to cell lysis. Before resuspending, briefly centrifuge the tube to ensure the lyophilized siRNA is at the bottom of the tube. Resuspend the siRNA oligos to an appropriate concentration with DEPC water. For each vial, suitable for 250 transfections in 24 well plate (20 pmol for each well).

Components

We offer pre-designed sets of 3 different target-specific siRNA oligo duplexes of human ZFP90 gene. Each vial contains 5 nmol of lyophilized siRNA. The duplexes can be transfected individually or pooled together to achieve knockdown of the target gene, which is most commonly assessed by qPCR or western blot. Our siRNA oligos are also chemically modified (2'-OMe) at no extra charge for increased stability and enhanced knockdown in vitro and in vivo.

Applications Tested/Suitable for ZFP90 sirna

RNA Interference (RNAi)

Other Notes

Small volumes of ZFP90 sirna vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for ZFP90. It may not necessarily be applicable to this product.

NCBI GI #

764020093

NCBI GeneID

146198

NCBI Accession #

NP_001292132.1

UniProt Primary Accession #

Q8TF47

UniProt Secondary Accession #

Q49AD1; Q96MQ6; B2RU00; B3KVE7; L7S2P3

UniProt Related Accession #

Q8TF47

GenBank Nucleotide #

NM_001305203.1

NCBI Official Full Name

zinc finger protein 90 homolog isoform 1

NCBI Official Synonym Full Names

ZFP90 zinc finger protein

NCBI Official Symbol

ZFP90

NCBI Official Synonym Symbols

FIK; NK10; ZNF756; zfp-90

UniProt Protein Name

Zinc finger protein 90 homolog

UniProt Synonym Protein Names

Zinc finger protein 756

Protein Family

Zinc finger protein

UniProt Gene Name

ZFP90

UniProt Synonym Gene Names

KIAA1954; ZNF756; Zfp-90

UniProt Entry Name

ZFP90_HUMAN

NCBI Protein Information

zinc finger protein 90 homolog

NCBI Summary for ZFP90

This gene encodes a member of the zinc finger protein family that modulates gene expression. The encoded protein derepresses the transcription of certain fetal cardiac genes and may contribute to the genetic reprogramming that occurs during the development of heart failure. Genome wide association studies have identified this gene among ulcerative colitis risk loci. Alternative splicing of this gene results in multiple transcript variants. [provided by RefSeq, Mar 2015]

UniProt Comments for ZFP90

ZFP90: May function as a repressor or silencer protein, and most likely exerts its repressing activity upon zinc-dependent binding to DNA. May be involved in proper spermatogenesis by repressing the expression of genes unnecessary or incompatible with the maintenance of a haploid cell state. Belongs to the krueppel C2H2-type zinc-finger protein family.

Protein type: C2H2-type zinc finger protein

Chromosomal Location of Human Ortholog: 16q22.1

Cellular Component: nucleus

Molecular Function: DNA binding; metal ion binding

Biological Process: transcription, DNA-dependent; positive regulation of transcription, DNA-dependent; negative regulation of transcription from RNA polymerase II promoter; negative regulation of DNA binding

Research Articles on ZFP90

1. Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator)

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with ZFP90 sirna

Products by Pathway	Pathway Diagram
Gene Expression Pathway antibodies	Gene Expression Pathway Diagram
Generic Transcription Pathway antibodies	Generic Transcription Pathway Diagram

Diseases associated with ZFP90 sirna

Disease Name	Pubmed Publications
Breast Neoplasms Antibodies	>1 publications with ZFP90 and Breast Neoplasms
Hepatitis Antibodies	>1 publications with ZFP90 and Hepatitis
Liver Diseases Antibodies	>1 publications with ZFP90 and Liver Diseases

Organs/Tissues associated with ZFP90 sirna

Organ/Tissue Name	Pubmed Publications
Thyroid Antibodies	>1 publications with ZFP90 and Thyroid
Liver Antibodies	>1 publications with ZFP90 and Liver
Heart Antibodies	>1 publications with ZFP90 and Heart
Blood Antibodies	>1 publications with ZFP90 and Blood
Brain Antibodies	>1 publications with ZFP90 and Brain