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Takinib Inhibitor

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS5750414

MBS5750414 is an inhibitor targeting Takinib. Takinib is a specific and effective TAK1 inhibitor(IC50= 9.5 nM). More details

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Product Documentation
PDF
Sample Manual Insert View PDF
PDF
Testing Data View PDF
PDF
Certificate of Analysis (COA) View PDF
PDF
QC Report View PDF
PDF
Material Safety Data Sheet View PDF
PDF
Technical Datasheet View PDF
PDF
Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
Takinib, Inhibitor
Full Product Name
Takinib
Product Synonym Names
MAP3K
Form/Format
POWDER
Purity/Purification
98.0%
Preparation and Storage
Powder: 3 years -20 degree C
In Solvent: 2 years -80 degree C
Molecular Weight
322.37
CAS Number
1111556-37-6
Formula
C18H18N4O2
Smiles
CCCN1C2=CC=CC=C2N=C1NC(=O)C3=CC=CC(=C3)C(=O)N
Solubility
DMSO: 6.8 mg/mL
Pathways
MAPK; ERK Pathway
Receptor
TAK1
Product Remark
For obtaining a higher solubility, please warm the tube at 37 degree C and shake it in the ultrasonic bath for a while. Stock solution can be stored below -20 degree C for several month.

Chemical Structure of Takinib, inhibitor

Takinib Inhibitor – Cat# MBS5750414

Product References and Citations for Takinib, inhibitor

1. Totzke J, et al. Takinib, a Selective TAK1 Inhibitor, Broadens the Therapeutic Efficacy of TNF-alpha Inhibition for Cancer and Autoimmune Disease. Cell Chem Biol. 2017 Aug 17; 24(8):1029-1039.

Other Notes

Small volumes of Takinib, inhibitor vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.
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