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EXO5 Lysate – Tissue Lysate

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS8411286

Human EXO5 Protein Lysate 20ug is provided as a Lyophilized powder.This is a Recombinant Protein Lysate produced in HEK293T cells. This protein lysate can be reconsituted using SDS Sample Buffer. More details

$390 / 0.02 mg +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
EXO5, Lysate
Full Product Name
Human EXO5 Protein Lysate
Product Gene Name
Product Synonym Names
EXO5; C1orf176; DEM1; Exo V; hExo5
Host
Human
Form/Format
Lyophilized
Preparation and Storage
Store at -20 degree C
Once reconsituted, aliquot and store any remaining material at-20 degree C to avoid repeated freeze-thaw cycles.
Molecular Weight
41kDa
3D Structure
ModBase 3D Structure for Q9H790

Other Notes

Small volumes of EXO5 lysate vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Searchable Terms for EXO5 purchase

MBS8411286 is a lysate targeting EXO5. Also known as Human EXO5 Protein Lysate. Host: Human.

Additional Details

NCBI/Uniprot data below describe general gene information for EXO5. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
exonuclease V
NCBI Official Synonym Full Names
exonuclease 5
NCBI Official Symbol
EXO5
NCBI Official Synonym Symbols
DEM1; Exo V; hExo5; C1orf176
UniProt Protein Name
Exonuclease V
UniProt Synonym Protein Names
Defects in morphology protein 1 homolog
Protein Family
UniProt Gene Name
EXO5
UniProt Synonym Gene Names
C1orf176; DEM1; Exo V; hExo5
NCBI Protein Information
exonuclease V

NCBI Summary for EXO5

The protein encoded by this gene is a single-stranded DNA (ssDNA)-specific exonuclease that can slide along the DNA before cutting it. However, human replication protein A binds ssDNA and restricts sliding of the encoded protein, providing a 5'-directionality to the enzyme. This protein localizes to nuclear repair loci after DNA damage. [provided by RefSeq, Nov 2016]
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UniProt Comments for EXO5

DEM1: Probable single strand DNA specific 5' exonuclease mitochondrial DNA replication and recombination. Belongs to the EXO5 family.

Protein type: EC 3.1.11.-

Chromosomal Location of Human Ortholog: 1p34.2

Cellular Component: cytosol; nucleoplasm; nucleus

Molecular Function: 4 iron, 4 sulfur cluster binding; DNA binding; metal ion binding; protein homodimerization activity; single-stranded DNA specific 3'-5'exodeoxyribonuclease activity; single-stranded DNA specific 5'-3'exodeoxyribonuclease activity

Biological Process: nucleic acid phosphodiester bond hydrolysis
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Diseases associated with EXO5 lysate

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