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NPR2 Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6170901

MBS6170901 is an antibody targeting NPR2. Also known as NPR2 (Natriuretic Peptide Receptor B/Guanylate Cyclase B (atrionatriuretic peptide Receptor B), AMDM, ANPRB, GUC2B, GUCY2B, NPRB, NPRBi) (Biotin). Host: Mouse. More details

$1140 / 0.1 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
NPR2, Monoclonal Antibody
Full Product Name
NPR2 (Natriuretic Peptide Receptor B/Guanylate Cyclase B (atrionatriuretic peptide Receptor B), AMDM, ANPRB, GUC2B, GUCY2B, NPRB, NPRBi) (Biotin)
Product Gene Name
Product Synonym Names
Natriuretic Peptide Receptor B/Guanylate Cyclase B (atrionatriuretic peptide Receptor B); AMDM; ANPRB; GUC2B; GUCY2B; NPRB; NPRBi
Clonality
Monoclonal
Isotype
IgG2b,k
Clone Number
10000
Host
Mouse
Form/Format
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Biotin.
Purity/Purification
Purified
Specificity
Recognizes NPR2.
Preparation and Storage
Store product at 4 degree C if to be used immediately within two weeks. For long-term storage, aliquot to avoid repeated freezing and thawing and store at -20 degree C. Aliquots are stable at -20 degree C for 12 months after receipt. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Molecular Weight
111,208 Da
3D Structure
ModBase 3D Structure for P20594
Immunogen
NPR2 (NP_003986.2, 131aa-230aa) partial recombinant protein with GST tag. MW of the GST tag alone is 26kD.
Immunogen Sequence
AKNDHYRTLVRTGPSAPKLGEFVVTLHGHFNWTARAALLYLDARTDDRPHYFTIEGVFEALQGSNLSVQHQVYAREPGGPEQATHFIRANGRIVYICGPL
Conjugate
Biotin

Product Categories/Family for anti-NPR2 antibody

Applications Tested/Suitable for anti-NPR2 antibody
Immunohistochemistry (IHC), Western Blot (WB)
Application Notes for anti-NPR2 antibody
Applications are based on unconjugated antibody.

Testing Data of anti-NPR2 antibody

Immunoperoxidase of monoclonal antibody to NPR2 on formalin-fixed paraffin-embedded human small Intestine. [antibody concentration 1 ug/ml]
Mouse Anti-NPR2 Monoclonal Antibody – Cat# MBS6170901

Immunohistochemistry (IHC) of anti-NPR2 antibody

Immunoperoxidase of monoclonal antibody to NPR2 on formalin-fixed paraffin-embedded human small Intestine. [antibody concentration 1 ug/ml]
Mouse Anti-NPR2 Monoclonal Antibody, Immunohistochemistry (IHC) – Cat# MBS6170901

Testing Data of anti-NPR2 antibody

Detection limit for recombinant GST tagged NPR2 is 3 ng/ml as a capture antibody.
Mouse Anti-NPR2 Monoclonal Antibody, Testing Data – Cat# MBS6170901

Other Notes

Small volumes of anti-NPR2 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for NPR2. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
atrial natriuretic peptide receptor 2
NCBI Official Synonym Full Names
natriuretic peptide receptor 2
NCBI Official Symbol
NPR2
NCBI Official Synonym Symbols
AMDM; ANPb; ECDM; NPRB; SNSK; ANPRB; GUC2B; NPRBi; GUCY2B
UniProt Protein Name
Atrial natriuretic peptide receptor 2
UniProt Synonym Protein Names
Atrial natriuretic peptide receptor type B; ANP-B; ANPR-B; NPR-B; Guanylate cyclase B; GC-B
UniProt Gene Name
NPR2
UniProt Synonym Gene Names
ANPRB; ANP-B; ANPR-B; NPR-B; GC-B
NCBI Protein Information
atrial natriuretic peptide receptor 2

NCBI Summary for NPR2

This gene encodes natriuretic peptide receptor B, one of two integral membrane receptors for natriuretic peptides. Both NPR1 and NPR2 contain five functional domains: an extracellular ligand-binding domain, a single membrane-spanning region, and intracellularly a protein kinase homology domain, a helical hinge region involved in oligomerization, and a carboxyl-terminal guanylyl cyclase catalytic domain. The protein is the primary receptor for C-type natriuretic peptide (CNP), which upon ligand binding exhibits greatly increased guanylyl cyclase activity. Mutations in this gene are the cause of acromesomelic dysplasia Maroteaux type. [provided by RefSeq, Jul 2008]
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UniProt Comments for NPR2

Receptor for the C-type natriuretic peptide NPPC/CNP hormone. Has guanylate cyclase activity upon binding of its ligand. May play a role in the regulation of skeletal growth.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Products associated with anti-NPR2 antibody

 Reference Product  PubMed Publications
 NPPC antibody  >14 publications with NPR2 and NPPC
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