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CD303/CLEC4C Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS1584936

MBS1584936 is an antibody targeting CD303/CLEC4C. Also known as Anti-Human CD303/CLEC4C Antibody (122A2), APC. Reactive in Human. Host: Mouse. More details

$415 / 50 Tests +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
CD303/CLEC4C, Monoclonal Antibody
Full Product Name
Anti-Human CD303/CLEC4C Antibody (122A2), APC
Product Synonym Names
CLEC4C; C-type lectin superfamily member 7; CLECSF11; C-type lectin domain family 4 member C; Dendritic lectin; CD303; DLEC; HECL; Blood dendritic cell antigen 2; BDCA-2; BDCA2; CLECSF7
Clonality
Monoclonal
Isotype
IgG1, kappa
Clone Number
122A2
Host
Mouse
Species Reactivity
Human
Form/Format
Liquid; 0.01M PBS, pH 7.4, 0.2% BSA, 0.05% Proclin 300.
Concentration
0.5mg/ml (lot specific)
Preparation and Storage
Store at 4 degree C for 12 months. Protect from light. Do not freeze.
Molecular Weight
25,038 Da
OMIM
606677
3D Structure
ModBase 3D Structure for Q8WTT0
Conjugation
APC
ISO Certification
Manufactured in an ISO 9001:2015 Certified Laboratory.
Applications Tested/Suitable for anti-CD303/CLEC4C antibody
Flow Cytometry (FC/FACS/FCM)

Other Notes

Small volumes of anti-CD303/CLEC4C antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for CD303/CLEC4C. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
C-type lectin domain family 4 member C isoform 2
NCBI Official Synonym Full Names
C-type lectin domain family 4, member C
NCBI Official Symbol
CLEC4C
NCBI Official Synonym Symbols
DLEC; HECL; BDCA2; CD303; CLECSF7; CLECSF11; PRO34150
UniProt Protein Name
C-type lectin domain family 4 member C
UniProt Synonym Protein Names
Blood dendritic cell antigen 2; BDCA-2; C-type lectin superfamily member 7; Dendritic lectin
UniProt Gene Name
CLEC4C
UniProt Synonym Gene Names
BDCA2; CLECSF11; CLECSF7; DLEC; HECL; BDCA-2
UniProt Entry Name
CLC4C_HUMAN
NCBI Protein Information
C-type lectin domain family 4 member C; BDCA-2; dendritic lectin; dendritic cell lectin b; C-type lectin superfamily member 7; blood dendritic cell antigen 2 protein; C-type lectin domain family 4, member C, isoform 1; C-type (calcium dependent, carbohydr

NCBI Summary for CD303/CLEC4C

This gene encodes a member of the C-type lectin/C-type lectin-like domain (CTL/CTLD) superfamily. Members of this family share a common protein fold and have diverse functions, such as cell adhesion, cell-cell signalling, glycoprotein turnover, and roles in inflammation and immune response. The encoded type 2 transmembrane protein may play a role in dendritic cell function. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]
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UniProt Comments for CD303/CLEC4C

CLEC4C: Involved in antigen-capturing. Target ligand into antigen processing and peptide-loading compartments for presentation to T-cells. May mediate potent inhibition of induction of IFN-alpha/beta expression in plasmacytoid dendritic cells. May act as a signaling receptor that activates protein- tyrosine kinases and mobilizes intracellular calcium. Does not seem to bind mannose. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Membrane protein, integral; Receptor, misc.

Chromosomal Location of Human Ortholog: 12p13.2-p12.3

Cellular Component: integral to membrane

Molecular Function: carbohydrate binding

Biological Process: innate immune response
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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