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CD5 Antibody – Mouse Monoclonal

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS6123995

MBS6123995 is an antibody targeting CD5. Also known as CD5 (CD5 antigen, p56 62, LEU1, Ly12, LyA, Lymphocyte antigen T1/Leu-1, Lymphocyte GlycoProtein T1/Leu1, T-cell surface GlycoProtein CD5) (APC). Reactive in Human. Host: Mouse. More details

$1105 / 0.1 mL +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
CD5, Monoclonal Antibody
Full Product Name
CD5 (CD5 antigen, p56 62, LEU1, Ly12, LyA, Lymphocyte antigen T1/Leu-1, Lymphocyte GlycoProtein T1/Leu1, T-cell surface GlycoProtein CD5) (APC)
Product Gene Name
Product Synonym Names
CD5 antigen; p56 62; LEU1; Ly12; LyA; Lymphocyte antigen T1/Leu-1; Lymphocyte GlycoProtein T1/Leu1; T-cell surface GlycoProtein CD5
Clonality
Monoclonal
Isotype
IgG1,k
Clone Number
SPM546
Host
Mouse
Species Reactivity
Human
Form/Format
Supplied as a liquid in 10mM PBS. No preservative added. BSA-Free. Labeled with Allophycocyanin (APC).
Purity/Purification
Purified by Protein A/G Affinity Chromatography.
Specificity
Recognizes human CD5.
Preparation and Storage
May be stored at 4 degree C before opening. DO NOT FREEZE! Stable at 4 degree C as an undiluted liquid. Dilute only prior to immediate use. Stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made in assay buffer. APC is light sensitive.
Molecular Weight
54,578 Da
Chromosome Location
Chromosome: 11; NC_000011.9 (60869930..60895324). Location: 11q13
OMIM
153340
3D Structure
ModBase 3D Structure for P06127
Immunogen
Human CD5 recombinant protein. Cellular Localization: Cell surface
Conjugate
APC
Positive Control
293T, Ramos, or MOLT-4 Cells. Tonsil.
Special Handling
Light sensitive

Product Categories/Family for anti-CD5 antibody

Applications Tested/Suitable for anti-CD5 antibody
Flow Cytometry (FC/FACS), FLISA, Immunofluorescence (IF), Immunohistochemistry (IHC), Immunoprecipitation (IP), Western Blot (WB)
Application Notes for anti-CD5 antibody
FC/FACS: 0.5-1ug/million cells
IP: 0.5-1ug/500ug protein lysate
IF: 0.5-1ug/ml
WB: 0.5-1ug/ml
IHC: 0.5-1ug/ml for 30 minutes at RT
Applications are based on unconjugated antibody.

Immunohistochemistry (IHC) of anti-CD5 antibody

Formalin-paraffin tonsil stained with CD5 MAb (SPM546)
Mouse Anti-CD5 Monoclonal Antibody – Cat# MBS6123995

Product References and Citations for anti-CD5 antibody

1. Ferry JA et. al. American Journal of Clinical Pathology, 1996, 105(1):31-7. 2. Gagneten D et. al. Diagnostic Cytopathology, 1996, 14(1):32-7.

Other Notes

Small volumes of anti-CD5 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for CD5. It may not necessarily be applicable to this product.

NCBI GI #
NCBI GeneID
NCBI Accession #
UniProt Primary Accession #
UniProt Secondary Accession #
UniProt Related Accession #
GenBank Nucleotide #
NCBI Official Full Name
T-cell surface glycoprotein CD5
NCBI Official Synonym Full Names
CD5 molecule
NCBI Official Symbol
CD5
NCBI Official Synonym Symbols
T1; LEU1
UniProt Protein Name
T-cell surface glycoprotein CD5
UniProt Synonym Protein Names
Lymphocyte antigen T1/Leu-1
UniProt Gene Name
CD5
UniProt Synonym Gene Names
LEU1
UniProt Entry Name
CD5_HUMAN
NCBI Protein Information
T-cell surface glycoprotein CD5; CD5 antigen (p56-62); lymphocyte antigen T1/Leu-1

UniProt Comments for CD5

CD5: a surface glycoprotein expressed on T cells and B-1 B cells. Rapidly recruited to the immunological synapse, lowering the response of the T cell antigen receptor. CD5 interacts with CD72/LYB-2. Promotes B-cell survival through stimulation of autocrine IL-10 production. Contains 3 SRCR domains.

Protein type: Cell surface; Membrane protein, integral

Chromosomal Location of Human Ortholog: 11q13

Cellular Component: integral to plasma membrane; plasma membrane; external side of plasma membrane

Molecular Function: protein binding; transmembrane receptor activity; receptor activity; scavenger receptor activity

Biological Process: receptor-mediated endocytosis; cell proliferation; T cell costimulation; cell recognition
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Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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