Rat Anti-CD146 Antibody – Cat# MBS2585722

Staining of C57BL/6 murine splenocytes cells with APC Anti-Mouse CD49b Antibody and Fluor<sup>®</sup> 488 Anti-Mouse NKG2A/C/E Antibody[ME-9F1] (left) or Fluor<sup>®</sup> 488 Rat IgG2a,κ Isotype Control (right). Total viable cells were used for analysis.

CD146 Antibody – Rat

Name: CD146 Antibody; Rat; Mouse-Reactive; Mouse-Reactive; MyBioSource
Brand: MyBioSource
SKU: MBS2585722
Price: 140 USD
Availability: InStock
Rating: 5 (10 reviews)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS2585722

MBS2585722 is an antibody targeting CD146. Also known as Fluor 488 Anti-Mouse CD146 Antibody [ME-9F1]. Reactive in Mouse. Host: Rat. More details

$140 / 50 Tests +1 FREE 8GB USB

Product Documentation

Sample Manual Insert View PDF

Testing Data View PDF

Certificate of Analysis (COA) View PDF

QC Report View PDF

Material Safety Data Sheet View PDF

Technical Datasheet View PDF

Protocol View PDF

Product Overview

Online Datasheet in PDF

Product Name

CD146, Antibody

Full Product Name

Fluor 488 Anti-Mouse CD146 Antibody [ME-9F1]

Product Gene Name

anti-CD146 antibody

Product Synonym Names

S-Endo 1 antigen; MUC18; MCAM; Mel-CAM; A32 antigen

Isotype

IgG2a, kappa

Clone Number

ME-9F1

Host

Rat

Species Reactivity

Mouse

Preparation and Storage

This product can be stored at 2-8 degree C for 12 months. Please protected from prolonged exposure to light and do not freeze.

Matching Pairs

Antibody: CD146 Clone #ME-9F1 (MBS2585722)
Isotype Control: IgG2a, kappa Clone #2A3 (MBS2557848)

Molecular Weight

39,204 Da

3D Structure

ModBase 3D Structure for P10810

Conjugation

Fluor488

Product Categories/Family for anti-CD146 antibody

Antibodies and Reagents; Primary Antibodies; Flow Cytometry Antibodies

ISO Certification

Manufactured in an ISO 9001:2015 Certified Laboratory.

Applications Tested/Suitable for anti-CD146 antibody

Flow Cytometry (FC/FACS)

Other Notes

Small volumes of anti-CD146 antibody vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for CD146. It may not necessarily be applicable to this product.

NCBI GI #

84004

NCBI GeneID

12475

NCBI Accession #

NP_033971.1

UniProt Primary Accession #

P10810

UniProt Related Accession #

P10810

GenBank Nucleotide #

NM_009841.4

NCBI Official Full Name

monocyte differentiation antigen CD14

NCBI Official Synonym Full Names

CD14 antigen

NCBI Official Symbol

Cd14

UniProt Protein Name

Monocyte differentiation antigen CD14

UniProt Synonym Protein Names

Myeloid cell-specific leucine-rich glycoprotein; CD_antigen: CD14

Protein Family

Cell surface glycoprotein

UniProt Gene Name

Cd14

UniProt Entry Name

CD14_MOUSE

NCBI Protein Information

monocyte differentiation antigen CD14

UniProt Comments for CD146

CD14: Cooperates with MD-2 and TLR4 to mediate the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Up-regulates cell surface molecules, including adhesion molecules.

Protein type: Membrane protein, GPI anchor

Cellular Component: anchored to external side of plasma membrane; cell surface; external side of plasma membrane; extracellular space; Golgi apparatus; lipid raft; lipopolysaccharide receptor complex; plasma membrane

Molecular Function: lipopolysaccharide binding

Biological Process: inflammatory response; lipopolysaccharide-mediated signaling pathway; positive regulation of cytokine secretion; positive regulation of endocytosis; positive regulation of interferon type I production; positive regulation of interferon-gamma production; positive regulation of tumor necrosis factor production; receptor-mediated endocytosis; response to bacterium; response to molecule of bacterial origin; toll-like receptor 4 signaling pathway

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

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