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NAT6 siRNA – N-Acetyltransferase 6 (Mouse)

For Research Use Only. Not for use in diagnostic procedures. Catalog #: MBS8233295

MBS8233295 is an siRNA targeting NAT6. Also known as NAT6 siRNA (Mouse). Reactive in Mouse. Host: Synthetic. siRNA to inhibit NAT6 expression using RNA interference More details

$480 / 15 nmol +1 FREE 8GB USB
Product Documentation
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Sample Manual Insert View PDF
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Testing Data View PDF
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Certificate of Analysis (COA) View PDF
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QC Report View PDF
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Material Safety Data Sheet View PDF
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Technical Datasheet View PDF
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Protocol View PDF

Product Overview

Online Datasheet in PDF
Product Name
NAT6, siRNA
Full Product Name
NAT6 siRNA (Mouse)
Product Gene Name
NAT6 sirna
Product Synonym Names
FUS2; N-acetyltransferase 6; Protein fusion-2; Protein fus-2
Host
Synthetic
Species Reactivity
Mouse
Form/Format
Lyophilized powder
Purity/Purification
> 97%
Specificity
NAT6 siRNA (Mouse) is a target-specific 19-23 nt siRNA oligo duplexes designed to knock down gene expression.
Preparation and Storage
Shipped at 4 degree C. Store at -20 degree C for one year.
Molecular Weight
34,583 Da
3D Structure
ModBase 3D Structure for Q9R123
Negative Control
siRNA Negative Control (Catalog# MBS8241404) is a non-targeting 21 nt siRNA recommended as a negative control for experiments using targeted siRNA transfection.
Quality Control
Oligonucleotide synthesis is monitored base by base through trityl analysis to ensure appropriate coupling efficiency. The oligo is subsequently purified by affinity-solid phase extraction. The annealed RNA duplex is further analyzed by mass spectrometry to verify the exact composition of the duplex. Each lot is compared to the previous lot by mass spectrometry to ensure maximum lot-to-lot consistency.
Directions for Use
We recommends transfection with 100 nM siRNA 48 to 72 hours prior to cell lysis. Before resuspending, briefly centrifuge the tube to ensure the lyophilized siRNA is at the bottom of the tube. Resuspend the siRNA oligos to an appropriate concentration with DEPC water. For each vial, suitable for 250 transfections in 24 well plate (20 pmol for each well).
Components
We offer pre-designed sets of 3 different target-specific siRNA oligo duplexes of mouse NAT6 gene. Each vial contains 5 nmol of lyophilized siRNA. The duplexes can be transfected individually or pooled together to achieve knockdown of the target gene, which is most commonly assessed by qPCR or western blot. Our siRNA oligos are also chemically modified (2'-OMe) at no extra charge for increased stability and enhanced knockdown in vitro and in vivo.
Applications Tested/Suitable for NAT6 sirna
RNA Interference (RNAi)

Other Notes

Small volumes of NAT6 sirna vial(s) may occasionally become entrapped in the seal of the product vial during shipment and storage. If necessary, briefly centrifuge the vial on a tabletop centrifuge to dislodge any liquid in the container`s cap. Certain products may require to ship with dry ice and additional dry ice fee may apply.

Additional Details

NCBI/Uniprot data below describe general gene information for NAT6. It may not necessarily be applicable to this product.

NCBI GI #
9789957
NCBI GeneID
56441
NCBI Accession #
NP_062724.1
UniProt Primary Accession #
Q9R123
UniProt Secondary Accession #
Q8QZY5; Q8R014; Q9ERM0
UniProt Related Accession #
Q9R123
GenBank Nucleotide #
NM_019750.3
NCBI Official Full Name
N-acetyltransferase 6
NCBI Official Synonym Full Names
N-acetyltransferase 6
NCBI Official Symbol
Nat6
NCBI Official Synonym Symbols
Fus2; AI225910
UniProt Protein Name
N-acetyltransferase 6
UniProt Synonym Protein Names
Protein fusion-2; Protein fus-2
Protein Family
N-acetyltransferase
UniProt Gene Name
Nat6
UniProt Synonym Gene Names
Fus2; Protein fus-2
UniProt Entry Name
NAT6_MOUSE
NCBI Protein Information
N-acetyltransferase 6

UniProt Comments for NAT6

NAT6: Seems to be involved in N-acetylation. Acts on peptides with a N-terminal Met followed by Asp/Glu/Asn. May act as a tumor suppressor. Belongs to the acetyltransferase family. 2 isoforms of the human protein are produced by alternative splicing.

Protein type: Tumor suppressor; Secondary Metabolites Metabolism - limonene and pinene degradation; Amino Acid Metabolism - tyrosine; Acetyltransferase; Amino Acid Metabolism - phenylalanine; EC 2.3.1.-; Lipid Metabolism - glycerophospholipid

Cellular Component: cytoplasm

Molecular Function: keto acid formate lyase activity; glucosaminyl-phosphotidylinositol O-acyltransferase activity; S-malonyltransferase activity; 3-hydroxybutyryl-CoA thiolase activity; S-acetyltransferase activity; O-octanoyltransferase activity; O-sinapoyltransferase activity; acyl-CoA N-acyltransferase activity; palmitoleoyl [acyl-carrier-protein]-dependent acyltransferase activity; peptidyl-lysine N6-myristoyltransferase activity; peptidyl-lysine N6-palmitoyltransferase activity; azetidine-2-carboxylic acid acetyltransferase activity; succinyltransferase activity; dihydrolipoamide branched chain acyltransferase activity; Ras palmitoyltransferase activity; palmitoyltransferase activity; C-acyltransferase activity; C-palmitoyltransferase activity; dihydrolipoamide S-acyltransferase activity; N-acetyltransferase activity; protein-cysteine S-acyltransferase activity; serine O-acyltransferase activity; malonyltransferase activity; O-palmitoyltransferase activity; octanoyltransferase activity; O-succinyltransferase activity; 3-ketopimelyl-CoA thiolase activity; sterol O-acyltransferase activity; carnitine O-acyltransferase activity; S-succinyltransferase activity; N-acyltransferase activity; UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase activity; N-palmitoyltransferase activity; O-acyltransferase activity; acylglycerol O-acyltransferase activity; O-acetyltransferase activity; transferase activity; benzoyl acetate-CoA thiolase activity; sinapoyltransferase activity; protein-cysteine S-myristoyltransferase activity; S-acyltransferase activity; N-succinyltransferase activity; acetyltransferase activity; myristoyltransferase activity; transferase activity, transferring acyl groups; L-2-aminoadipate N-acetyltransferase activity
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Research Articles on NAT6

1. Characterization of the murine hyaluronidase gene region reveals complex organization and cotranscription of Hyal1 with downstream genes, Fus2 and Hyal3.

Precautions

All of MyBioSource's Products are for scientific laboratory research purposes and are not for diagnostic, therapeutics, prophylactic or in vivo use. Through your purchase, you expressly represent and warrant to MyBioSource that you will properly test and use any Products purchased from MyBioSource in accordance with industry standards. MyBioSource and its authorized distributors reserve the right to refuse to process any order where we reasonably believe that the intended use will fall outside of our acceptable guidelines.

Disclaimer

While every efforts were made to ensure the accuracy of the information provided in this datasheet, MyBioSource will not be liable for any omissions or errors contained herein. MyBioSource reserves the right to make changes to this datasheet at any time without prior notice.

It is the responsibility of the customer to report product performance issues to MyBioSource within 30 days of receipt of the product. Please visit our Terms & Conditions page for more information.

Product Note

Select online data sheet information is drawn from bioinformatics databases, occasionally resulting in ambiguous or non-relevant product information. It is the responsibility of the customer to review, verify, and evaluate the information to make sure it matches their requirements before purchasing the kit. Our ELISA Kit assays are dynamic research tools and sometimes they may be updated and improved. If the format of this assay is important to you then please request the current manual or contact our technical support team with a presales inquiry before placing an order. We will confirm the current details of the assay. We cannot guarantee the sample manual posted online is the most current manual, it is intended to serve as an example only. Please refer to the instructions For Use provided with the assay kit for precise details.

Product PubMed Publications

Pathways associated with NAT6 sirna

 Products by Pathway  Pathway Diagram
 Metapathway Biotransformation antibodies  Metapathway Biotransformation Diagram

Organs/Tissues associated with NAT6 sirna

 Organ/Tissue Name  Pubmed Publications
 Muscle Antibodies  >1 publications with NAT6 and Muscle
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